产品简要
公司名称 :
StressMarq Biosciences
产品类型 :
抗体
产品名称 :
HSP70抗体
目录 :
SMC-100B
规格 :
200微克
价格 :
324美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
C92F3A-5
反应物种 :
Sus, 人类, 小鼠, 大鼠, , pigs
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 流式细胞仪, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 61
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 6h, 2g, 6s1e
Azkanaz M, Rodríguez López A, de Boer B, Huiting W, Angrand P, Vellenga E, et al. Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 1
  • 免疫印迹基因敲除验证; 小鼠; 1:3000; 图 2
Chittoor Vinod V, Lee S, Judge S, Notterpek L. Inducible HSP70 is critical in preventing the aggregation and enhancing the processing of PMP22. ASN Neuro. 2015;7: pubmed 出版商
  • 免疫印迹; 人类
Seguin S, Morelli F, Vinet J, Amore D, De Biasi S, Poletti A, et al. Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly. Cell Death Differ. 2014;21:1838-51 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Eroglu B, Kimbler D, Pang J, Choi J, Moskophidis D, Yanasak N, et al. Therapeutic inducers of the HSP70/HSP110 protect mice against traumatic brain injury. J Neurochem. 2014;130:626-41 pubmed 出版商
  • 免疫印迹; 大鼠
Akkad H, Corpeno R, Larsson L. Masseter muscle myofibrillar protein synthesis and degradation in an experimental critical illness myopathy model. PLoS ONE. 2014;9:e92622 pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000
Wijeratne E, Xu Y, Scherz Shouval R, Marron M, Rocha D, Liu M, et al. Structure-activity relationships for withanolides as inducers of the cellular heat-shock response. J Med Chem. 2014;57:2851-63 pubmed 出版商
  • 免疫印迹; 小鼠
Sheppard P, Sun X, Khammash M, Giffard R. Overexpression of heat shock protein 72 attenuates NF-?B activation using a combination of regulatory mechanisms in microglia. PLoS Comput Biol. 2014;10:e1003471 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6
Bauckman K, Haller E, Flores I, Nanjundan M. Iron modulates cell survival in a Ras- and MAPK-dependent manner in ovarian cells. Cell Death Dis. 2013;4:e592 pubmed 出版商
  • 免疫印迹; pigs
  • 免疫印迹; Sus
Aare S, Radell P, Eriksson L, Akkad H, Chen Y, Hoffman E, et al. Effects of corticosteroids in the development of limb muscle weakness in a porcine intensive care unit model. Physiol Genomics. 2013;45:312-20 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500
Larkins N, Murphy R, Lamb G. Influences of temperature, oxidative stress, and phosphorylation on binding of heat shock proteins in skeletal muscle fibers. Am J Physiol Cell Physiol. 2012;303:C654-65 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Abisambra J, Jinwal U, Suntharalingam A, Arulselvam K, Brady S, Cockman M, et al. DnaJA1 antagonizes constitutive Hsp70-mediated stabilization of tau. J Mol Biol. 2012;421:653-61 pubmed 出版商
  • 免疫印迹; 人类; 1:3000
Santagata S, Xu Y, Wijeratne E, Kontnik R, Rooney C, Perley C, et al. Using the heat-shock response to discover anticancer compounds that target protein homeostasis. ACS Chem Biol. 2012;7:340-9 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Patterson K, Ward S, Combs B, Voss K, Kanaan N, Morfini G, et al. Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport. Biochemistry. 2011;50:10300-10 pubmed 出版商
  • 免疫印迹; pigs
  • 免疫印迹; Sus
Aare S, Ochala J, Norman H, Radell P, Eriksson L, Göransson H, et al. Mechanisms underlying the sparing of masticatory versus limb muscle function in an experimental critical illness model. Physiol Genomics. 2011;43:1334-50 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500
Larkins N, Murphy R, Lamb G. Absolute amounts and diffusibility of HSP72, HSP25, and ?B-crystallin in fast- and slow-twitch skeletal muscle fibers of rat. Am J Physiol Cell Physiol. 2012;302:C228-39 pubmed 出版商
  • 免疫沉淀; 人类; 1:50
Shipp C, Watson K, Jones G. Associations of HSP90 client proteins in human breast cancer. Anticancer Res. 2011;31:2095-101 pubmed
  • 免疫组化; 人类; 1:50
  • 免疫印迹; 人类; 1:10000
Wood J, Pring M, Eveson J, Price N, Proby C, Hague A. Co-overexpression of Bag-1 and heat shock protein 70 in human epidermal squamous cell carcinoma: Bag-1-mediated resistance to 5-fluorouracil-induced apoptosis. Br J Cancer. 2011;104:1459-71 pubmed 出版商
  • 免疫印迹; 大鼠
Ochala J, Gustafson A, Diez M, Renaud G, Li M, Aare S, et al. Preferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: underlying mechanisms. J Physiol. 2011;589:2007-26 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
Batista Nascimento L, Neef D, Liu P, Rodrigues Pousada C, Thiele D. Deciphering human heat shock transcription factor 1 regulation via post-translational modification in yeast. PLoS ONE. 2011;6:e15976 pubmed 出版商
  • 免疫印迹; 人类; 1:10000
Mitsuhashi M, Yamaguchi M, Kojima T, Nakajima R, Kasai K. Effects of HSP70 on the compression force-induced TNF-? and RANKL expression in human periodontal ligament cells. Inflamm Res. 2011;60:187-94 pubmed 出版商
  • 免疫印迹; 人类
Fernández Llama P, Khositseth S, Gonzales P, Star R, Pisitkun T, Knepper M. Tamm-Horsfall protein and urinary exosome isolation. Kidney Int. 2010;77:736-42 pubmed 出版商
  • 免疫印迹; Sus
  • 免疫印迹; pigs
Banduseela V, Ochala J, Chen Y, Göransson H, Norman H, Radell P, et al. Gene expression and muscle fiber function in a porcine ICU model. Physiol Genomics. 2009;39:141-59 pubmed 出版商
  • 免疫印迹; 大鼠
Zwang N, Hoffert J, Pisitkun T, Moeller H, Fenton R, Knepper M. Identification of phosphorylation-dependent binding partners of aquaporin-2 using protein mass spectrometry. J Proteome Res. 2009;8:1540-54 pubmed 出版商
  • 免疫印迹; 小鼠
Xu Y, Marron M, Seddon E, McLaughlin S, Ray D, Whitesell L, et al. 2,3-Dihydrowithaferin A-3beta-O-sulfate, a new potential prodrug of withaferin A from aeroponically grown Withania somnifera. Bioorg Med Chem. 2009;17:2210-4 pubmed 出版商
Zhang Y, VanHecke G, Ahn Y, Proby C, Dinkova Kostova A. Sulfoxythiocarbamate S-4 inhibits HSP90 in human cutaneous squamous cell carcinoma cells. Eur J Pharmacol. 2020;889:173609 pubmed 出版商
Fang C, Kuo H, Hsu S, Yih L. HSP70 regulates Eg5 distribution within the mitotic spindle and modulates the cytotoxicity of Eg5 inhibitors. Cell Death Dis. 2020;11:715 pubmed 出版商
Kuta R, Larochelle N, Fernandez M, Pal A, Minotti S, Tibshirani M, et al. Depending on the stress, histone deacetylase inhibitors act as heat shock protein co-inducers in motor neurons and potentiate arimoclomol, exerting neuroprotection through multiple mechanisms in ALS models. Cell Stress Chaperones. 2020;25:173-191 pubmed 出版商
von Horn C, Minor T. Transient hyperthermia during oxygenated rewarming of isolated rat livers. Transpl Int. 2020;33:272-278 pubmed 出版商
Koyama S, Narita E, Suzuki Y, Shiina T, Taki M, Shinohara N, et al. Long-term exposure to a 40-GHz electromagnetic field does not affect genotoxicity or heat shock protein expression in HCE-T or SRA01/04 cells. J Radiat Res. 2019;60:417-423 pubmed 出版商
Portillo J, Van Grol J, Saffo S, Lopez Corcino Y, Rodríguez M, Fox B, et al. CD40 in endothelial cells restricts neural tissue invasion by Toxoplasma gondii. Infect Immun. 2019;: pubmed 出版商
Wadhwa R, Li L, Singh R, Wang J, Gao R, Nigam N, et al. Modulation of Diacylglycerol-Induced Melanogenesis in Human Melanoma and Primary Melanocytes: Role of Stress Chaperone Mortalin. Evid Based Complement Alternat Med. 2019;2019:9848969 pubmed 出版商
Arnold F, Pluciennik A, Merry D. Impaired Nuclear Export of Polyglutamine-Expanded Androgen Receptor in Spinal and Bulbar Muscular Atrophy. Sci Rep. 2019;9:119 pubmed 出版商
Ueda T, Kohama Y, Sakurai H. IER family proteins are regulators of protein phosphatase PP2A and modulate the phosphorylation status of CDC25A. Cell Signal. 2019;55:81-89 pubmed 出版商
Kitano S, Kondo T, Matsuyama R, Ono K, Goto R, Takaki Y, et al. Impact of hepatic HSP72 on insulin signaling. Am J Physiol Endocrinol Metab. 2019;316:E305-E318 pubmed 出版商
Tian Z, Dong C, Fujita A, Fujita Y, Hashimoto K. Expression of heat shock protein HSP-70 in the retrosplenial cortex of rat brain after administration of (R,S)-ketamine and (S)-ketamine, but not (R)-ketamine. Pharmacol Biochem Behav. 2018;172:17-21 pubmed 出版商
Jin X, Qiao A, Moskophidis D, Mivechi N. Modulation of Heat Shock Factor 1 Activity through Silencing of Ser303/Ser307 Phosphorylation Supports a Metabolic Program Leading to Age-Related Obesity and Insulin Resistance. Mol Cell Biol. 2018;38: pubmed 出版商
Girard P, Peynot N, Lelièvre J. Differential correlations between changes to glutathione redox state, protein ubiquitination, and stress-inducible HSPA chaperone expression after different types of oxidative stress. Cell Stress Chaperones. 2018;23:985-1002 pubmed 出版商
Yukawa H, Suzuki K, Aoki K, Arimoto T, Yasui T, Kaji N, et al. Imaging of angiogenesis of human umbilical vein endothelial cells by uptake of exosomes secreted from hepatocellular carcinoma cells. Sci Rep. 2018;8:6765 pubmed 出版商
Muralidharan S, Lim A, Catalano D, Mandrekar P. Human Binge Alcohol Intake Inhibits TLR4-MyD88 and TLR4-TRIF Responses but Not the TLR3-TRIF Pathway: HspA1A and PP1 Play Selective Regulatory Roles. J Immunol. 2018;200:2291-2303 pubmed 出版商
Bhattacharya K, Bernasconi L, Picard D. Luminescence resonance energy transfer between genetically encoded donor and acceptor for protein-protein interaction studies in the molecular chaperone HSP70/HSP90 complexes. Sci Rep. 2018;8:2801 pubmed 出版商
Stangl S, Foulds G, Fellinger H, Pilkington G, Pockley A, Multhoff G. Immunohistochemical and Flow Cytometric Analysis of Intracellular and Membrane-Bound Hsp70, as a Putative Biomarker of Glioblastoma Multiforme, Using the cmHsp70.1 Monoclonal Antibody. Methods Mol Biol. 2018;1709:307-320 pubmed 出版商
Jin X, Qiao A, Moskophidis D, Mivechi N. WITHDRAWN: Abrogation of heat shock factor 1 (Hsf1) phosphorylation deregulates its activity and lowers activation threshold, leading to obesity in mice. J Biol Chem. 2017;: pubmed 出版商
Qiao A, Jin X, Pang J, Moskophidis D, Mivechi N. The transcriptional regulator of the chaperone response HSF1 controls hepatic bioenergetics and protein homeostasis. J Cell Biol. 2017;216:723-741 pubmed 出版商
Katoh H, Kubota T, Nakatsu Y, Tahara M, Kidokoro M, Takeda M. Heat Shock Protein 90 Ensures Efficient Mumps Virus Replication by Assisting with Viral Polymerase Complex Formation. J Virol. 2017;91: pubmed 出版商
Kawaguchi Y, Taoka M, Takekiyo T, Uekita T, Shoji I, Hachiya N, et al. TRIM32-Cytoplasmic-Body Formation Is an ATP-Consuming Process Stimulated by HSP70 in Cells. PLoS ONE. 2017;12:e0169436 pubmed 出版商
Ogilvie H, Cacciani N, Akkad H, Larsson L. Targeting Heat Shock Proteins Mitigates Ventilator Induced Diaphragm Muscle Dysfunction in an Age-Dependent Manner. Front Physiol. 2016;7:417 pubmed
Koyama S, Narita E, Shimizu Y, Shiina T, Taki M, Shinohara N, et al. Twenty Four-Hour Exposure to a 0.12 THz Electromagnetic Field Does Not Affect the Genotoxicity, Morphological Changes, or Expression of Heat Shock Protein in HCE-T Cells. Int J Environ Res Public Health. 2016;13: pubmed 出版商
Hu Y, Wang Y, Liang S, Yu X, Zhang L, Feng L, et al. Senkyunolide I attenuates oxygen-glucose deprivation/reoxygenation-induced inflammation in microglial cells. Brain Res. 2016;1649:123-131 pubmed 出版商
Koyama S, Narita E, Shimizu Y, Suzuki Y, Shiina T, Taki M, et al. Effects of Long-Term Exposure to 60 GHz Millimeter-Wavelength Radiation on the Genotoxicity and Heat Shock Protein (Hsp) Expression of Cells Derived from Human Eye. Int J Environ Res Public Health. 2016;13: pubmed 出版商
Kunihiro M, Fujii H, Miyagi T, Takahashi Y, Tanaka R, Fukushima T, et al. Heat Shock Enhances the Expression of the Human T Cell Leukemia Virus Type-I (HTLV-I) Trans-Activator (Tax) Antigen in Human HTLV-I Infected Primary and Cultured T Cells. Viruses. 2016;8: pubmed 出版商
Dayalan Naidu S, Sutherland C, Zhang Y, Risco A, de La Vega L, Caunt C, et al. Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases. Mol Cell Biol. 2016;36:2403-17 pubmed 出版商
Katoh H, Kubota T, Kita S, Nakatsu Y, Aoki N, Mori Y, et al. Heat shock protein 70 regulates degradation of the mumps virus phosphoprotein via the ubiquitin-proteasome pathway. J Virol. 2015;89:3188-99 pubmed 出版商
Richter C, Viergutz T, Schwerin M, Weitzel J. Prostaglandin E synthase interacts with inducible heat shock protein 70 after heat stress in bovine primary dermal fibroblast cells. Cytometry A. 2015;87:61-7 pubmed 出版商
Engels M, Bilgic E, Pinto A, Vásquez E, Wollschläger L, Steinbrenner H, et al. A cardiopulmonary bypass with deep hypothermic circulatory arrest rat model for the investigation of the systemic inflammation response and induced organ damage. J Inflamm (Lond). 2014;11:26 pubmed 出版商
Dang V, Tanabe K, Tanaka Y, Tokumoto N, Misumi T, Saeki Y, et al. Fasting enhances TRAIL-mediated liver natural killer cell activity via HSP70 upregulation. PLoS ONE. 2014;9:e110748 pubmed 出版商
Ishikawa Y, Sakurai H. Heat-induced expression of the immediate-early gene IER5 and its involvement in the proliferation of heat-shocked cells. FEBS J. 2015;282:332-40 pubmed 出版商
Berger A, Ivanova E, Gareau C, Scherrer A, Mazroui R, Strub K. Direct binding of the Alu binding protein dimer SRP9/14 to 40S ribosomal subunits promotes stress granule formation and is regulated by Alu RNA. Nucleic Acids Res. 2014;42:11203-17 pubmed 出版商
Kanegasaki S, Matsushima K, Shiraishi K, Nakagawa K, Tsuchiya T. Macrophage inflammatory protein derivative ECI301 enhances the alarmin-associated abscopal benefits of tumor radiotherapy. Cancer Res. 2014;74:5070-8 pubmed 出版商
Muralidharan S, Ambade A, Fulham M, Deshpande J, Catalano D, Mandrekar P. Moderate alcohol induces stress proteins HSF1 and hsp70 and inhibits proinflammatory cytokines resulting in endotoxin tolerance. J Immunol. 2014;193:1975-87 pubmed 出版商
Preusse Prange A, Modrow J, Schwark T, von Wurmb Schwark N. Detection of constitutive and inducible HSP70 proteins in formalin fixed human brain tissue. Forensic Sci Int. 2014;235:62-7 pubmed 出版商
Chanoux R, Robay A, Shubin C, Kebler C, Suaud L, Rubenstein R. Hsp70 promotes epithelial sodium channel functional expression by increasing its association with coat complex II and its exit from endoplasmic reticulum. J Biol Chem. 2012;287:19255-65 pubmed 出版商
图像
图像 1 :
StressMarq Biosciences SMC-100B 图像 1
Immunohistochemistry analysis using Mouse Anti-Hsp70 Monoclonal Antibody, Clone C92F3A-5 (SMC-100). Tissue: colon carcinoma. Species: Mouse. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp70 Monoclonal Antibody (SMC-100) at 1:10000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. This image was produced using an amplifying IHC wash buffer. The antibody has therefore been diluted more than is recommended for other applications.
产品信息
目录# :
SMC-100B
产品名称 :
HSP70抗体
产品类型 :
抗体
宿主物种 :
小鼠
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
C92F3A-5
规格 :
200微克
标价美元 :
324美元
产品描述 :
小鼠抗人类HSP70单克隆IgG1
物种活性培养基 :
Human Mouse Rat Bovine C. elegans Dog Chicken Drosophila Carp Guinea Pig Hamster Monkey Pig Rabbit Sheep
别称(s) :
HSP70 1抗体, HSP70 2抗体, HSP70.1抗体, HSP72抗体, HSPA1抗体, HSPA1A抗体, HSPA1B抗体
免疫原 :
人类HSP70
Cellular Localization :
细胞质
特异性 :
Detects ~70kDa. Does not cross-react with HSC70 (HSP73).
纯化 :
蛋白质G纯化
浓度 :
1毫克/毫升
应用 :
WB IHC ICC/IF ELISA FCM FACS IEM Bl AM
更多信息或购买 :
公司信息
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
公司总部: 加拿大
StressMarq Biosciences Inc.是由Dr.Louwrier创建与温哥华的维多利亚,专注于热休克、细胞压力、离子通道及细胞信号研究领域,提供大量经过严格验证的抗体、蛋白及试剂盒。公司致力于提供高质量试剂以满足并超越客户期望。它也推出抗体试用项目,特别针对于新的研究领域,鼓励客户在购买之前先测试小规格试用产品。此外,公司提供采用新专利免疫组化技术的试剂盒,采用前所未有的抗体浓度进行实验。