产品简要
公司名称 :
StressMarq Biosciences
产品类型 :
抗体
产品名称 :
DNA/RNA Damage Antibody
目录 :
SMC-155
规格 :
25微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
15A3
反应物种 :
人类
应用 :
酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
StressMarq Biosciences 产品网页
文章摘录数: 20
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类
Aboud O, Mrak R, Boop F, Griffin W. Epilepsy: neuroinflammation, neurodegeneration, and APOE genotype. Acta Neuropathol Commun. 2013;1:41 pubmed 出版商
Cheli V, Santiago González D, Wan Q, Denaroso G, Wan R, Rosenblum S, et al. H-ferritin expression in astrocytes is necessary for proper oligodendrocyte development and myelination. Glia. 2021;69:2981-2998 pubmed 出版商
Greenwald S, Brown E, Scandura M, Hennessey E, Farmer R, Du J, et al. Mutant Nmnat1 leads to a retina-specific decrease of NAD+ accompanied by increased poly(ADP-ribose) in a mouse model of NMNAT1-associated retinal degeneration. Hum Mol Genet. 2021;30:644-657 pubmed 出版商
Sule G, Abuaita B, Steffes P, Fernandes A, Estes S, Dobry C, et al. Endoplasmic reticulum stress sensor IRE1α propels neutrophil hyperactivity in lupus. J Clin Invest. 2021;131: pubmed 出版商
Attri A, Thakur D, Kaur T, Sensale S, Peng Z, Kumar D, et al. Nanoparticles Incorporating a Fluorescence Turn-on Reporter for Real-Time Drug Release Monitoring, a Chemoenhancer and a Stealth Agent: Poseidon's Trident against Cancer?. Mol Pharm. 2021;18:124-147 pubmed 出版商
Bakewell S, Conde I, Fallah Y, McCoy M, Jin L, Shajahan Haq A. Inhibition of DNA Repair Pathways and Induction of ROS Are Potential Mechanisms of Action of the Small Molecule Inhibitor BOLD-100 in Breast Cancer. Cancers (Basel). 2020;12: pubmed 出版商
Wu P, Scarlata E, O Flaherty C. Long-Term Adverse Effects of Oxidative Stress on Rat Epididymis and Spermatozoa. Antioxidants (Basel). 2020;9: pubmed 出版商
Flis S, Bratek E, Chojnacki T, Piskorek M, Skorski T. Simultaneous Inhibition of BCR-ABL1 Tyrosine Kinase and PAK1/2 Serine/Threonine Kinase Exerts Synergistic Effect against Chronic Myeloid Leukemia Cells. Cancers (Basel). 2019;11: pubmed 出版商
Komakula S, Tumová J, Kumaraswamy D, Burchat N, Vartanian V, Ye H, et al. The DNA Repair Protein OGG1 Protects Against Obesity by Altering Mitochondrial Energetics in White Adipose Tissue. Sci Rep. 2018;8:14886 pubmed 出版商
Cui S, Lv X, Li W, Li Z, Liu H, Gao Y, et al. Folic acid modulates VPO1 DNA methylation levels and alleviates oxidative stress-induced apoptosis in vivo and in vitro. Redox Biol. 2018;19:81-91 pubmed 出版商
Amini P, Stojkov D, Felser A, Jackson C, Courage C, Schaller A, et al. Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nat Commun. 2018;9:2958 pubmed 出版商
Lai J, Wang M, Huang C, Wu C, Hung L, Yang C, et al. Infection with the dengue RNA virus activates TLR9 signaling in human dendritic cells. EMBO Rep. 2018;19: pubmed 出版商
Alhadidi Q, Nash K, Alaqel S, Sayeed M, Shah Z. Cofilin Knockdown Attenuates Hemorrhagic Brain Injury-induced Oxidative Stress and Microglial Activation in Mice. Neuroscience. 2018;383:33-45 pubmed 出版商
Angeloni C, Teti G, Barbalace M, Malaguti M, Falconi M, Hrelia S. 17β-Estradiol enhances sulforaphane cardioprotection against oxidative stress. J Nutr Biochem. 2017;42:26-36 pubmed 出版商
Liu Y, O Flaherty C. In vivo oxidative stress alters thiol redox status of peroxiredoxin 1 and 6 and impairs rat sperm quality. Asian J Androl. 2017;19:73-79 pubmed 出版商
Lood C, Blanco L, Purmalek M, Carmona Rivera C, De Ravin S, Smith C, et al. Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease. Nat Med. 2016;22:146-53 pubmed 出版商
Angeloni C, Malaguti M, Rizzo B, Barbalace M, Fabbri D, Hrelia S. Neuroprotective effect of sulforaphane against methylglyoxal cytotoxicity. Chem Res Toxicol. 2015;28:1234-45 pubmed 出版商
Ozkosem B, Feinstein S, Fisher A, O Flaherty C. Advancing age increases sperm chromatin damage and impairs fertility in peroxiredoxin 6 null mice. Redox Biol. 2015;5:15-23 pubmed 出版商
Zawada W, Mrak R, Biedermann J, Palmer Q, Gentleman S, Aboud O, et al. Loss of angiotensin II receptor expression in dopamine neurons in Parkinson's disease correlates with pathological progression and is accompanied by increases in Nox4- and 8-OH guanosine-related nucleic acid oxidation and caspase-3 activation. Acta Neuropathol Commun. 2015;3:9 pubmed 出版商
Brennan L, Haukedal J, Earle J, Keddie B, Harris H. Disruption of redox homeostasis leads to oxidative DNA damage in spermatocytes of Wolbachia-infected Drosophila simulans. Insect Mol Biol. 2012;21:510-20 pubmed 出版商
图像
图像 1 :
StressMarq Biosciences SMC-155 图像 1
Immunohistochemistry analysis using Mouse Anti-DNA Damage Monoclonal Antibody, Clone 15A3 (SMC-155). Tissue: Retinal Injury Model. Species: Mouse. Primary Antibody: Mouse Anti-DNA Damage Monoclonal Antibody (SMC-155) at 1:1000. Secondary Antibody: Alexa Fluor 594 Goat Anti-Mouse (red). Courtesy of: Dr. Rajashekhar Gangaraju, University of Indiana, Department of Ophthalmology, Eugene and Marilyn Glick Eye Institute.
产品信息
目录号 :
SMC-155
产品名称 :
DNA/RNA Damage Antibody
描述 :
Mouse Anti- DNA/RNA Damage Monoclonal IgG2b
靶标 :
DNA损伤
研究领域(s) :
Cancer Oxidative Stress Cell Signaling Post-translational Modifications Oxidation Cell Signaling Epigenetics and Nuclear Signaling DNA/RNA DNA Damage and Repair
别称(s) :
8-Hydroxy Guanine Antibody, 8-OH-dG Antibody, 8OHG Antibody, 80G Antibody, 8 hydroxyguanine Antibody, 8 hydroxy 2' deoxyguanosine Antibody, 8 hydroxyguanosine Antibody, 8 OHG Antibody, 8-OHG Antibody, 8OHdG Antibody
类别 :
抗体
产品类型 :
单克隆
克隆编号 :
15A3
免疫原 :
8-hydroxy-guanosine-BSA and –casein conjugates
应用 :
免疫组化免疫细胞化学/IF酶联免疫吸附测定DB免疫沉淀FCM FA
宿主物种 :
小鼠
抗体亚型 :
IgG2b
物种活性培养基 :
Species Independent
抗体稀释 :
IHC (1:1000); optimal dilutions for assays should be determined by the user.
纯化 :
蛋白质G纯化
特异性 :
Recognizes markers of oxidative damage to DNA (8-hydroxy-2'-deoxyguanosine, 8-hydroxyguanine and 8-hydroxyguanosine).
规格1 :
25微克
规格2 :
100微克
更多信息或购买 :
StressMarq Biosciences 产品网页
公司信息
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
公司总部: 加拿大
StressMarq Biosciences Inc.是由Dr.Louwrier创建与温哥华的维多利亚，专注于热休克、细胞压力、离子通道及细胞信号研究领域，提供大量经过严格验证的抗体、蛋白及试剂盒。公司致力于提供高质量试剂以满足并超越客户期望。它也推出抗体试用项目，特别针对于新的研究领域，鼓励客户在购买之前先测试小规格试用产品。此外，公司提供采用新专利免疫组化技术的试剂盒，采用前所未有的抗体浓度进行实验。