产品简要
公司名称 :
StressMarq Biosciences
产品类型 :
抗体
产品名称 :
PARP抗体
目录 :
SMC-259D
规格 :
100微升
价格 :
260.00美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
M3
反应物种 :
人类
应用 :
免疫印迹
更多信息或购买 :
StressMarq Biosciences 产品网页
图像
图像 1 :
StressMarq Biosciences SMC-259D 图像 1
Western Blot analysis of Human Embryonic kidney epithelial cell line (HEK293) showing detection of ~113 kDa PARP protein using Mouse Anti-PARP Monoclonal Antibody, Clone M3 (SMC-259). Lane 1: Human HeLa. Lane 2: Human 293T. Lane 3: Human Jurkat. Primary Antibody: Mouse Anti-PARP Monoclonal Antibody (SMC-259) at 1:2000. Predicted/Observed Size: ~113 kDa.
产品信息
目录号 :
SMC-259D
产品名称 :
PARP抗体
描述 :
小鼠抗人类PARP单克隆IgG1
靶标 :
PARP
共轭标签 :
未共轭
2021标价 :
260.00美元
Currency :
美元
研究领域(s) :
Cell Signaling Epigenetics and Nuclear Signaling Chromatin Modifying Enzymes ADP-ribosylation DNA/RNA DNA Damage and Repair Base excision repair DNA Damage Recognition
别称(s) :
ADP ribosyltransferase (NAD+; poly (ADP ribose) polymerase) antibody, ADP ribosyltransferase diphtheria toxin like 1 antibody, ADP ribosyltransferase NAD(+) antibody, ADPRT 1 antibody, ADPRT antibody, ADPRT1 antibody, ARTD1 antibody, msPARP antibody, NAD(+) ADP ribosyltransferase 1 antibody, NAD(+) ADP-ribosyltransferase 1 antibody, pADPRT 1 antibody, pADPRT1 antibody, PARP 1 antibody, PARP antibody, PARP-1 antibody, PARP1 antibody, PARP1_HUMAN antibody, Poly (ADP ribose) polymerase 1 antibody, poly (ADP ribose) polymerase family, member 1 antibody, Poly [ADP-ribose] polymerase 1 antibody, Poly(ADP ribose) polymerase antibody, poly(ADP ribose) synthetase antibody, poly(ADP ribosyl)transferase antibody, Poly[ADP ribose] synthetase 1 antibody, Poly[ADP-ribose] synthase 1 antibody, PPOL antibody
规格 :
100微升
类别 :
抗体
产品类型 :
单克隆
克隆编号 :
M3
免疫原 :
A synthesized peptide derived from human PARP
免疫原物种 :
人类
登录号 :
NP_001609.2
Swiss Prot数据库 :
P09874
应用 :
免疫印迹
宿主物种 :
小鼠
抗体亚型 :
IgG1
物种活性缩写 :
Hu
物种活性全称 :
人类
抗体稀释 :
WB (1:2000); optimal dilutions for assays should be determined by the user.
纯化 :
肽亲和纯化
储存缓冲液 :
PBS (without Mg2+ and Ca2+), 50% glycerol, pH 7.4, 150mM NaCl, 0.02% sodium azide
特异性 :
Antibody can detects endogenous PARP protein.
储存温度 :
-20ºC
运输温度 :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SMC-259D, RRID: AB_2699808
化验分析证明书 :
A 1:2000 dilution of SMC-259 was sufficient for detection of PARP in 10 µg of Human HeLa, 293T, Jurkat cell lysates by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.
Cellular Localization :
Nucleus
科研背景 :
Poly (ADP-ribose) polymerase (PARP) is a family of proteins involved in a number of cellular processes involving mainly DNA repair and programmed cell death. It is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
参考文献 :
1. Piskunova TS. (2008) Curr Gerontol Geriatr Res: 754190. 2. Espinoza LA. et al. (2007) Free Radic. Biol. Med. 42 (9): 1430–40. 3. Zerfaoui M. et al. (2008) Cell. Signal. 20 (1): 186–94.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SMC-259_PARP_Antibody_WB_Human_HeLa_293
T_Jurkat_1.png
更多信息或购买 :
StressMarq Biosciences 产品网页
公司信息
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
公司总部: 加拿大
StressMarq Biosciences Inc.是由Dr.Louwrier创建与温哥华的维多利亚，专注于热休克、细胞压力、离子通道及细胞信号研究领域，提供大量经过严格验证的抗体、蛋白及试剂盒。公司致力于提供高质量试剂以满足并超越客户期望。它也推出抗体试用项目，特别针对于新的研究领域，鼓励客户在购买之前先测试小规格试用产品。此外，公司提供采用新专利免疫组化技术的试剂盒，采用前所未有的抗体浓度进行实验。