产品简要
公司名称 :
StressMarq Biosciences
产品类型 :
抗体
产品名称 :
基质金属蛋白酶9抗体
目录 :
SMC-396D
规格 :
100微克
价格 :
300.00美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
S51-82
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
文章摘录数: 3
| 参考文献 |
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产品信息
目录号 :
SMC-396D
产品名称 :
基质金属蛋白酶9抗体
描述 :
小鼠抗大鼠基质金属蛋白酶9单克隆IgG2a
靶标 :
基质金属蛋白酶9
共轭标签 :
未共轭
2021标价 :
300.00美元
Currency :
美元
研究领域(s) :
Cardiovascular System Angiogenesis Cardiovascular Growth Factors Adhesion / Extracellular Matrix Matrix Metalloproteinases Cell Signaling Extracellular Matrix (ECM) Enzymes Cell Signaling Extracellular Matrix (ECM) Enzymes Cancer Tumor Biomarkers Tumor Biomarker Enzymes Cancer Invasion/microenvironment
别称(s) :
MMP-9 Antibody, CLG4B Antibody, 82kDa matrix metalloproteinase-9 Antibody, collagenease type 4 beta Antibody, GELB Antibody, Macrophage gelatinase Antibody, MANDP2 Antibody, Type V collagenase Antibody, 92 kDa gelatinase Antibody, 92 kDa type IV collagenase Antibody, Gelatinase B Antibody, MMP9 Antibody, Matrix metalloproteinase 9 Antibody
规格 :
100微克
类别 :
抗体
产品类型 :
单克隆
克隆编号 :
S51-82
免疫原 :
Fusion protein amino acids 1-708 (full length) of rat MMP9
免疫原物种 :
大鼠
登录号 :
NP_112317.1
Swiss Prot数据库 :
P50282
应用 :
免疫印迹免疫组化免疫细胞化学/IF免疫沉淀FCM
宿主物种 :
小鼠
抗体亚型 :
IgG2a
物种活性缩写 :
Hu Ms Rt
物种活性全称 :
人类小鼠大鼠
抗体稀释 :
WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
纯化 :
蛋白质G纯化
储存缓冲液 :
PBS pH7.4, 50% 甘油, 0.09% 叠氮化钠
浓度 :
1毫克/毫升
特异性 :
Detecs ~92kDa and ~82kDa (pro and active forms).
储存温度 :
-20ºC
运输温度 :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SMC-396D, RRID: AB_11232604
化验分析证明书 :
1 µg/ml of SMC-396 was sufficient for detection of MMP9 in 20 µg of COS-1 cells (lysate) transfected with human MMP9 by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Cellular Localization :
细胞外间质
科研背景 :
MMP9, otherwise known as matrix metalloproteinase 9, is involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction and tissue remodeling, as well as in disease processes like arthritis and metastasis (1). Among the family members, MMP-2, MMP-3, MMP-7 and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis (2-4). MMP activity correlates with cancer development (2). One mechanism of MMP regulation is transcriptional (5). Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein (5).
参考文献 :
1. Hirose Y., et al. (2008) Am J Hum Genet. 82(5): 1122-1129.
2. Coussens L.M., et al. (2002) Science 295: 2387-2391.
3. Sternlicht M.D., et al. (1999) Cell 98: 137-146.
4. Vu T.H., et al. (1998) Cell 93: 411-422.
5. Nagase H., et al. (1990) Biochemistry 29: 5783-5789.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SMC-396_MMP9_Antibody_S51-82_ICC-IF_Mouse_NIH-3T3-Mouse-Fibroblast-cell-line_60X_Composite_1.png SMC-396_MMP9_Antibody_S51-82_WB_Rat_Brain_1.png
更多信息或购买 :
公司信息
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com1-250-294-9065
公司总部: 加拿大
StressMarq Biosciences Inc.是由Dr.Louwrier创建与温哥华的维多利亚，专注于热休克、细胞压力、离子通道及细胞信号研究领域，提供大量经过严格验证的抗体、蛋白及试剂盒。公司致力于提供高质量试剂以满足并超越客户期望。它也推出抗体试用项目，特别针对于新的研究领域，鼓励客户在购买之前先测试小规格试用产品。此外，公司提供采用新专利免疫组化技术的试剂盒，采用前所未有的抗体浓度进行实验。