产品简要
公司名称 :
StressMarq Biosciences
产品类型 :
抗体
产品名称 :
LRRK2/Dardarin Antibody
目录 :
SMC-446D
规格 :
100微克
价格 :
300.00美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
S138-6
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学
更多信息或购买 :
产品信息
目录号 :
SMC-446D
产品名称 :
LRRK2/Dardarin Antibody
描述 :
Mouse Anti-Human LRRK2/Dardarin Monoclonal IgG1
靶标 :
LRRK2
共轭标签 :
未共轭
2021标价 :
300.00美元
Currency :
美元
研究领域(s) :
Neuroscience Neurodegeneration Parkinson's Disease Cell Signaling Post-translational Modifications Phosphorylation
别称(s) :
Leucine-rich repeat kinase 2 Antibody, RIP7 Antibody, PARK8 Antibody, Dardarin Antibody, ROCO 2 Antibody, RIPK7 Antibody, Leucine-rich repeat serine/threonine-protein kinase 2 Antibody, augmented in rheumatoid arthritis 17 Antibody
规格 :
100微克
类别 :
抗体
产品类型 :
单克隆
克隆编号 :
S138-6
免疫原 :
Fusion protein, amino acids 1-500 (N-terminus) of human LRRK2. 83% identical in mouse and rat. No significant identity with LRRK1.
免疫原物种 :
人类
登录号 :
NP_940980
Swiss Prot数据库 :
Q5S007
应用 :
免疫印迹免疫细胞化学/IF
宿主物种 :
小鼠
抗体亚型 :
IgG1
物种活性缩写 :
Hu Ms Rt
物种活性全称 :
人类小鼠大鼠
抗体稀释 :
WB (1:1000); optimal dilutions for assays should be determined by the user.
纯化 :
蛋白质G纯化
储存缓冲液 :
PBS pH值7.4, 50% 甘油, 0.1% 叠氮化钠
浓度 :
1毫克/毫升
特异性 :
Detects >200kDa.
储存温度 :
-20ºC
运输温度 :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SMC-446D, RRID: AB_2701775
化验分析证明书 :
1 µg/ml of SMC-446 was sufficient for detection of LRRK2/Dardarin in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Cellular Localization :
细胞质膜线粒体高尔基体细胞投射轴突树突内质网细胞质囊泡内涵体
溶体
科研背景 :
LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SMC-446-LRRK2-Dardarin-Antibody-S138-6-ICC-IF-Human-Neuroblastoma-cell-line-SK-N-BE-60X-Composite-1.png SMC-446-LRRK2-Dardarin-Antibody-S138-6-WB-Rat-Brain-Membrane-1.png
更多信息或购买 :
公司信息
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com1-250-294-9065
公司总部: 加拿大
StressMarq Biosciences Inc.是由Dr.Louwrier创建与温哥华的维多利亚，专注于热休克、细胞压力、离子通道及细胞信号研究领域，提供大量经过严格验证的抗体、蛋白及试剂盒。公司致力于提供高质量试剂以满足并超越客户期望。它也推出抗体试用项目，特别针对于新的研究领域，鼓励客户在购买之前先测试小规格试用产品。此外，公司提供采用新专利免疫组化技术的试剂盒，采用前所未有的抗体浓度进行实验。