产品简要
公司名称 :
Synaptic Systems
产品类型 :
抗体
产品名称 :
突触素1
目录 :
101 011
规格 :
50微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
07. Feb
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 128
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 小鼠; 1:1000; 图 1d
Quadros A, Arazola R, xc1 lvarez A, Pires J, Meredith R, Saarloos I, et al. Neuronal F-Box protein FBXO41 regulates synaptic transmission and hippocampal network maturation. iScience. 2022;25:104069 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4e
Pérez Sisqués L, Sancho Balsells A, Solana Balaguer J, Campoy Campos G, Vives Isern M, Soler Palazón F, et al. RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer's disease. Cell Death Dis. 2021;12:616 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 9a
Kim W, Watanabe H, Lomoio S, Tesco G. Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo. J Biol Chem. 2021;296:100372 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 3c
Steinkellner T, Madany M, Haberl M, Zell V, Li C, Hu J, et al. Genetic Probe for Visualizing Glutamatergic Synapses and Vesicles by 3D Electron Microscopy. ACS Chem Neurosci. 2021;12:626-639 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5b
Sclip A, Sudhof T. LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses. elife. 2020;9: pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 4a
Su J, Charalambakis N, Sabbagh U, Somaiya R, Monavarfeshani A, Guido W, et al. Retinal inputs signal astrocytes to recruit interneurons into visual thalamus. Proc Natl Acad Sci U S A. 2020;117:2671-2682 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1a
  • 免疫印迹; 人类; 图 s1j
Patzke C, Brockmann M, Dai J, Gan K, Grauel M, Fenske P, et al. Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses. Cell. 2019;179:498-513.e22 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 3s1a
Kaczmarek Hájek K, Zhang J, Kopp R, Grosche A, Rissiek B, Saul A, et al. Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody. elife. 2018;7: pubmed 出版商
  • 免疫印迹; 小鼠; 图 s1c
Liu C, Kershberg L, Wang J, Schneeberger S, Kaeser P. Dopamine Secretion Is Mediated by Sparse Active Zone-like Release Sites. Cell. 2018;172:706-718.e15 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 1
  • 免疫印迹; 小鼠; 图 1
Bodaleo F, Montenegro Venegas C, Henríquez D, Court F, Gonzalez Billault C. Microtubule-associated protein 1B (MAP1B)-deficient neurons show structural presynaptic deficiencies in vitro and altered presynaptic physiology. Sci Rep. 2016;6:30069 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3a
Sclip A, Bacaj T, Giam L, Sudhof T. Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction. PLoS ONE. 2016;11:e0158295 pubmed 出版商
  • 免疫组化; 小鼠; 图 4a
  • 免疫印迹; 小鼠; 图 2b
Emanuele M, Esposito A, Camerini S, Antonucci F, Ferrara S, Seghezza S, et al. Exogenous Alpha-Synuclein Alters Pre- and Post-Synaptic Activity by Fragmenting Lipid Rafts. EBioMedicine. 2016;7:191-204 pubmed 出版商
  • 免疫印迹; 人类
Patzke C, Acuna C, Giam L, Wernig M, Südhof T. Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation. J Exp Med. 2016;213:499-515 pubmed 出版商
  • 免疫组化; 小鼠; 图 1
Gazit N, Vertkin I, Shapira I, Helm M, Slomowitz E, Sheiba M, et al. IGF-1 Receptor Differentially Regulates Spontaneous and Evoked Transmission via Mitochondria at Hippocampal Synapses. Neuron. 2016;89:583-97 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000
Ferreira J, Schmidt J, Rio P, Águas R, Rooyakkers A, Li K, et al. GluN2B-Containing NMDA Receptors Regulate AMPA Receptor Traffic through Anchoring of the Synaptic Proteasome. J Neurosci. 2015;35:8462-79 pubmed 出版商
  • 免疫组化; 小鼠
Usui Y, Westenskow P, Kurihara T, Aguilar E, Sakimoto S, Paris L, et al. Neurovascular crosstalk between interneurons and capillaries is required for vision. J Clin Invest. 2015;125:2335-46 pubmed 出版商
  • 免疫印迹; 大鼠
Ronzitti G, Bucci G, Emanuele M, Leo D, Sotnikova T, Mus L, et al. Exogenous ?-synuclein decreases raft partitioning of Cav2.2 channels inducing dopamine release. J Neurosci. 2014;34:10603-15 pubmed 出版商
  • 免疫印迹; 大鼠
Zhao H, Kim Y, Park J, Park D, Lee S, Chang I, et al. SCAMP5 plays a critical role in synaptic vesicle endocytosis during high neuronal activity. J Neurosci. 2014;34:10085-95 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫组化; 小鼠
  • 免疫印迹; 小鼠
  • 免疫细胞化学; 大鼠
  • 免疫组化; 大鼠
  • 免疫印迹; 大鼠
Wilhelm B, Mandad S, Truckenbrodt S, Kr hnert K, Sch fer C, Rammner B, et al. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Science. 2014;344:1023-8 pubmed 出版商
  • 免疫印迹; 小鼠
Biesemann C, Gr Nborg M, Luquet E, Wichert S, Bernard V, Bungers S, et al. Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting. EMBO J. 2014;33:157-70 pubmed 出版商
  • 免疫组化; 小鼠
Del Rio T, Nishitani A, Yu W, Goodrich L. In vivo analysis of Lrig genes reveals redundant and independent functions in the inner ear. PLoS Genet. 2013;9:e1003824 pubmed 出版商
  • 免疫细胞化学; 大鼠
Agostini F, Dotti C, P rez Ca am s A, Ledesma M, Benetti F, Legname G. Prion protein accumulation in lipid rafts of mouse aging brain. PLoS ONE. 2013;8:e74244 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 1
Koh J, Iwabuchi S, Harata N. Dystonia-associated protein torsinA is not detectable at the nerve terminals of central neurons. Neuroscience. 2013;253:316-29 pubmed 出版商
  • 免疫印迹; 小鼠
Caba ero D, Baker A, Zhou S, Hargett G, Irie T, Xia Y, et al. Pain after discontinuation of morphine treatment is associated with synaptic increase of GluA4-containing AMPAR in the dorsal horn of the spinal cord. Neuropsychopharmacology. 2013;38:1472-84 pubmed 出版商
  • 免疫组化; 小鼠
Liu Z, Owen T, Fang J, Zuo J. Overactivation of Notch1 signaling induces ectopic hair cells in the mouse inner ear in an age-dependent manner. PLoS ONE. 2012;7:e34123 pubmed 出版商
  • 免疫组化; 小鼠
Fujita E, Tanabe Y, Imhof B, Momoi M, Momoi T. Cadm1-expressing synapses on Purkinje cell dendrites are involved in mouse ultrasonic vocalization activity. PLoS ONE. 2012;7:e30151 pubmed 出版商
  • 免疫细胞化学; 小鼠
Loske P, Boato F, Hendrix S, Piepgras J, Just I, Ahnert Hilger G, et al. Minimal essential length of Clostridium botulinum C3 peptides to enhance neuronal regenerative growth and connectivity in a non-enzymatic mode. J Neurochem. 2012;120:1084-96 pubmed 出版商
  • 免疫印迹; 小鼠
Yeh F, Dong M, Yao J, Tepp W, Lin G, Johnson E, et al. SV2 mediates entry of tetanus neurotoxin into central neurons. PLoS Pathog. 2010;6:e1001207 pubmed 出版商
  • 免疫细胞化学; 小鼠
Dabrowski M, Aerts S, Van Hummelen P, Craessaerts K, De Moor B, Annaert W, et al. Gene profiling of hippocampal neuronal culture. J Neurochem. 2003;85:1279-88 pubmed
Hoffmann Conaway S, Brockmann M, Schneider K, Annamneedi A, Rahman K, Bruns C, et al. Parkin contributes to synaptic vesicle autophagy in Bassoon-deficient mice. elife. 2020;9: pubmed 出版商
Eldahan K, Williams H, Cox D, Gollihue J, Patel S, Rabchevsky A. Paradoxical effects of continuous high dose gabapentin treatment on autonomic dysreflexia after complete spinal cord injury. Exp Neurol. 2020;323:113083 pubmed 出版商
Esposito A, Falace A, Wagner M, Gal M, Mei D, Conti V, et al. Biallelic DMXL2 mutations impair autophagy and cause Ohtahara syndrome with progressive course. Brain. 2019;142:3876-3891 pubmed 出版商
Xiao S, McKeever P, Lau A, Robertson J. Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels. Acta Neuropathol Commun. 2019;7:161 pubmed 出版商
Ackermann F, Schink K, Bruns C, Izsvák Z, Hamra F, Rosenmund C, et al. Critical role for Piccolo in synaptic vesicle retrieval. elife. 2019;8: pubmed 出版商
Petrov A, Lam M, Mast N, Moon J, Li Y, Maxfield E, et al. CYP46A1 Activation by Efavirenz Leads to Behavioral Improvement without Significant Changes in Amyloid Plaque Load in the Brain of 5XFAD Mice. Neurotherapeutics. 2019;: pubmed 出版商
Lee J, Lee S, Ryu Y, Lee D, Kim S, Seo J, et al. Vaccinia-related kinase 2 plays a critical role in microglia-mediated synapse elimination during neurodevelopment. Glia. 2019;: pubmed 出版商
Van Gool B, Storck S, Reekmans S, Lechat B, Gordts P, Pradier L, et al. LRP1 Has a Predominant Role in Production over Clearance of Aβ in a Mouse Model of Alzheimer's Disease. Mol Neurobiol. 2019;: pubmed 出版商
Fenske P, Grauel M, Brockmann M, Dorrn A, Trimbuch T, Rosenmund C. Autaptic cultures of human induced neurons as a versatile platform for studying synaptic function and neuronal morphology. Sci Rep. 2019;9:4890 pubmed 出版商
Ono Y, Mori Y, Egashira Y, Sumiyama K, Takamori S. Expression of plasma membrane calcium ATPases confers Ca2+/H+ exchange in rodent synaptic vesicles. Sci Rep. 2019;9:4289 pubmed 出版商
Chung J, Franklin J, Lee H. Central expression of synaptophysin and synaptoporin in nociceptive afferent subtypes in the dorsal horn. Sci Rep. 2019;9:4273 pubmed 出版商
Malik A, Szydlowska K, Nizinska K, Asaro A, van Vliet E, Popp O, et al. SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology. Cell Rep. 2019;26:2792-2804.e6 pubmed 出版商
de Pins B, Cifuentes Diaz C, Farah A, López Molina L, Montalban E, Sancho Balsells A, et al. Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease. J Neurosci. 2019;39:2441-2458 pubmed 出版商
Milesi C, Alberici P, Pozzi B, Oldani A, Beznoussenko G, Raimondi A, et al. Redundant and nonredundant organismal functions of EPS15 and EPS15L1. Life Sci Alliance. 2019;2: pubmed 出版商
Hoffmann S, Orlando M, Andrzejak E, Bruns C, Trimbuch T, Rosenmund C, et al. Light-Activated ROS Production Induces Synaptic Autophagy. J Neurosci. 2019;39:2163-2183 pubmed 出版商
Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, et al. Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting. Science. 2019;363: pubmed 出版商
Kindt K, SHEETS L. Transmission Disrupted: Modeling Auditory Synaptopathy in Zebrafish. Front Cell Dev Biol. 2018;6:114 pubmed 出版商
Boeri J, Le Corronc H, Lejeune F, Le Bras B, Mouffle C, Angelim M, et al. Persistent Sodium Current Drives Excitability of Immature Renshaw Cells in Early Embryonic Spinal Networks. J Neurosci. 2018;38:7667-7682 pubmed 出版商
Truckenbrodt S, Viplav A, Jähne S, Vogts A, Denker A, Wildhagen H, et al. Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission. EMBO J. 2018;37: pubmed 出版商
Hruska M, Henderson N, Le Marchand S, Jafri H, Dalva M. Synaptic nanomodules underlie the organization and plasticity of spine synapses. Nat Neurosci. 2018;21:671-682 pubmed 出版商
Farsi Z, Gowrisankaran S, Krunic M, Rammner B, Woehler A, Lafer E, et al. Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity. elife. 2018;7: pubmed 出版商
Martins F, Marafona A, Pereira C, Müller T, Loosse C, Kolbe K, et al. Identification and characterization of the BRI2 interactome in the brain. Sci Rep. 2018;8:3548 pubmed 出版商
Park D, Chang S. Soluble Aβ1-42 increases the heterogeneity in synaptic vesicle pool size among synapses by suppressing intersynaptic vesicle sharing. Mol Brain. 2018;11:10 pubmed 出版商
Richter K, Schmutz I, Darna M, Zander J, Chavan R, Albrecht U, et al. VGLUT1 Binding to Endophilin or Intersectin1 and Dynamin Phosphorylation in a Diurnal Context. Neuroscience. 2018;371:29-37 pubmed 出版商
Riemann D, Wallrafen R, Dresbach T. The Kohlschütter-Tönz syndrome associated gene Rogdi encodes a novel presynaptic protein. Sci Rep. 2017;7:15791 pubmed 出版商
Nakaya N, Sultana A, Tomarev S. Impaired AMPA receptor trafficking by a double knockout of zebrafish olfactomedin1a/b. J Neurochem. 2017;143:635-644 pubmed 出版商
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Terni B, Pacciolla P, Masanas H, Gorostiza P, Llobet A. Tight temporal coupling between synaptic rewiring of olfactory glomeruli and the emergence of odor-guided behavior in Xenopus tadpoles. J Comp Neurol. 2017;525:3769-3783 pubmed 出版商
Bröker Lai J, Kollewe A, Schindeldecker B, Pohle J, Nguyen Chi V, Mathar I, et al. Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory. EMBO J. 2017;36:2770-2789 pubmed 出版商
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Daniel J, Cooper B, Palvimo J, Zhang F, Brose N, Tirard M. Analysis of SUMO1-conjugation at synapses. elife. 2017;6: pubmed 出版商
Su Y, Yuan Y, Feng S, Ma S, Wang Y. High frequency stimulation induces sonic hedgehog release from hippocampal neurons. Sci Rep. 2017;7:43865 pubmed 出版商
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Liu T, Li H, Hong W, Han W. Brefeldin A-inhibited guanine nucleotide exchange protein 3 is localized in lysosomes and regulates GABA signaling in hippocampal neurons. J Neurochem. 2016;139:748-756 pubmed 出版商
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Acuna C, Liu X, Sudhof T. How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs. Neuron. 2016;91:792-807 pubmed 出版商
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Amin H, Maccione A, Marinaro F, Zordan S, Nieus T, Berdondini L. Electrical Responses and Spontaneous Activity of Human iPS-Derived Neuronal Networks Characterized for 3-month Culture with 4096-Electrode Arrays. Front Neurosci. 2016;10:121 pubmed 出版商
Rajappa R, Gauthier Kemper A, Böning D, Hüve J, Klingauf J. Synaptophysin 1 Clears Synaptobrevin 2 from the Presynaptic Active Zone to Prevent Short-Term Depression. Cell Rep. 2016;14:1369-1381 pubmed 出版商
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Cheng C, Wang W, Huang C, Du P, Yang J, Tsaur M. Coexpression of auxiliary subunits KChIP and DPPL in potassium channel Kv4-positive nociceptors and pain-modulating spinal interneurons. J Comp Neurol. 2016;524:846-73 pubmed 出版商
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Jadhav S, Katina S, Kovac A, Kazmerova Z, Novak M, Zilka N. Truncated tau deregulates synaptic markers in rat model for human tauopathy. Front Cell Neurosci. 2015;9:24 pubmed 出版商
Binotti B, Pavlos N, Riedel D, Wenzel D, Vorbrüggen G, Schalk A, et al. The GTPase Rab26 links synaptic vesicles to the autophagy pathway. elife. 2015;4:e05597 pubmed 出版商
Mollinari C, Racaniello M, Berry A, Pieri M, de Stefano M, Cardinale A, et al. miR-34a regulates cell proliferation, morphology and function of newborn neurons resulting in improved behavioural outcomes. Cell Death Dis. 2015;6:e1622 pubmed 出版商
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Rodriguez Espinosa N, Fernandez Espejo E. Effects of acute and repeated cocaine on markers for neural plasticity within the mesolimbic system in rats. Psychopharmacology (Berl). 2015;232:57-62 pubmed 出版商
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Ahmed S, Holt M, Riedel D, Jahn R. Small-scale isolation of synaptic vesicles from mammalian brain. Nat Protoc. 2013;8:998-1009 pubmed 出版商
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Bouyer K, Simerly R. Neonatal leptin exposure specifies innervation of presympathetic hypothalamic neurons and improves the metabolic status of leptin-deficient mice. J Neurosci. 2013;33:840-51 pubmed 出版商
Wei S, Soh S, Qiu W, Yang W, Seah C, Guo J, et al. Seipin regulates excitatory synaptic transmission in cortical neurons. J Neurochem. 2013;124:478-89 pubmed 出版商
Huupponen J, Molchanova S, Lauri S, Taira T. Ongoing intrinsic synchronous activity is required for the functional maturation of CA3-CA1 glutamatergic synapses. Cereb Cortex. 2013;23:2754-64 pubmed 出版商
Ricciardi S, Ungaro F, Hambrock M, Rademacher N, Stefanelli G, Brambilla D, et al. CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons. Nat Cell Biol. 2012;14:911-23 pubmed 出版商
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Vasileva M, Horstmann H, Geumann C, Gitler D, Kuner T. Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission. Eur J Neurosci. 2012;36:3005-20 pubmed 出版商
Schmeisser M, Baumann B, Johannsen S, Vindedal G, Jensen V, Hvalby Ø, et al. I?B kinase/nuclear factor ?B-dependent insulin-like growth factor 2 (Igf2) expression regulates synapse formation and spine maturation via Igf2 receptor signaling. J Neurosci. 2012;32:5688-703 pubmed 出版商
Raingo J, Khvotchev M, Liu P, Darios F, Li Y, Ramirez D, et al. VAMP4 directs synaptic vesicles to a pool that selectively maintains asynchronous neurotransmission. Nat Neurosci. 2012;15:738-45 pubmed 出版商
Blum F, Chen C, Kroken A, Barbieri J. Tetanus toxin and botulinum toxin a utilize unique mechanisms to enter neurons of the central nervous system. Infect Immun. 2012;80:1662-9 pubmed 出版商
Görlich A, Wolf M, Zimmermann A, Gurniak C, Al Banchaabouchi M, Sassoè Pognetto M, et al. N-cofilin can compensate for the loss of ADF in excitatory synapses. PLoS ONE. 2011;6:e26789 pubmed 出版商
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Barth J, Zimmermann H, Volknandt W. SV31 is a Zn2+-binding synaptic vesicle protein. J Neurochem. 2011;118:558-70 pubmed 出版商
Gomes J, Lobo A, Melo C, Inácio A, Takano J, Iwata N, et al. Cleavage of the vesicular GABA transporter under excitotoxic conditions is followed by accumulation of the truncated transporter in nonsynaptic sites. J Neurosci. 2011;31:4622-35 pubmed 出版商
Treppmann P, Brunk I, Afube T, Richter K, Ahnert Hilger G. Neurotoxic phospholipases directly affect synaptic vesicle function. J Neurochem. 2011;117:757-64 pubmed 出版商
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产品信息
Cat. Nr. :
101 011
抗原 :
突触素1
同义词 :
p38-1, Synaptophysin1
宿主物种 :
小鼠
Tpye :
单克隆
形式 :
纯化IgG
细胞系 :
07. Feb
亚类 :
IgG1
免疫原 :
Recombinant protein corresponding to AA 1 to 307 from rat Synaptophysin1 (UniProt Id: P07825)
反应物种 :
人类, 大鼠, 小鼠, 哺乳动物, 斑马鱼, 其他脊椎动物
免疫印迹 :
免疫印迹
免疫沉淀 :
免疫沉淀
免疫细胞化学 :
免疫细胞化学
免疫组化 :
免疫组化
免疫组化P :
免疫组化-P
EM :
EM
酶联免疫吸附测定 :
酶联免疫吸附测定
KO :
yes
KD :
yes
规格 :
50微克
更多信息或购买 :
公司信息
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
公司总部: 德国