产品简要
公司名称 :
Synaptic Systems
产品类型 :
抗体
产品名称 :
SNAP25
目录 :
111 011
规格 :
50微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
71.1
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 45
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 大鼠
Ivanova D, Dobson K, Gajbhiye A, Davenport E, Hacker D, Ultanir S, et al. Control of synaptic vesicle release probability via VAMP4 targeting to endolysosomes. Sci Adv. 2021;7: pubmed 出版商
  • 免疫组化; 小鼠; 1:1000
Arias Hervert E, Xu N, Njus M, Murphy G, Hou Y, Williams J, et al. Actions of Rab27B-GTPase on mammalian central excitatory synaptic transmission. Physiol Rep. 2020;8:e14428 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1f
Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, et al. Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting. Science. 2019;363: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3i
Lüningschrör P, Binotti B, Dombert B, Heimann P, Pérez Lara A, Slotta C, et al. Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease. Nat Commun. 2017;8:678 pubmed 出版商
  • 免疫细胞化学; 大鼠; 图 8a
  • 免疫印迹; 小鼠; 图 4
Vazquez Cintron E, Beske P, Tenezaca L, Tran B, Oyler J, Glotfelty E, et al. Engineering Botulinum Neurotoxin C1 as a Molecular Vehicle for Intra-Neuronal Drug Delivery. Sci Rep. 2017;7:42923 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 5a
Wolfes A, Ahmed S, Awasthi A, Stahlberg M, Rajput A, Magruder D, et al. A novel method for culturing stellate astrocytes reveals spatially distinct Ca2+ signaling and vesicle recycling in astrocytic processes. J Gen Physiol. 2017;149:149-170 pubmed 出版商
  • 免疫沉淀; 大鼠; 图 4a
  • 免疫印迹; 大鼠; 1:1000; 图 3a
Takeuchi S, Iwama S, Takagi H, Kiyota A, Nakashima K, Izumida H, et al. Tomosyn Negatively Regulates Arginine Vasopressin Secretion in Embryonic Stem Cell-Derived Neurons. PLoS ONE. 2016;11:e0164544 pubmed 出版商
  • 免疫组化; 大鼠; 1:2000; 图 4
Zhang S, Wang P, Ren L, Hu C, Bi J. Protective effect of melatonin on soluble A?1-42-induced memory impairment, astrogliosis, and synaptic dysfunction via the Musashi1/Notch1/Hes1 signaling pathway in the rat hippocampus. Alzheimers Res Ther. 2016;8:40 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4e
Toft Bertelsen T, Ziomkiewicz I, Houy S, Pinheiro P, Sørensen J. Regulation of Ca2+ channels by SNAP-25 via recruitment of syntaxin-1 from plasma membrane clusters. Mol Biol Cell. 2016;27:3329-3341 pubmed
  • 免疫印迹; 大鼠; 图 1
Wang C, Wang Y, Hu M, Chai Z, Wu Q, Huang R, et al. Synaptotagmin-11 inhibits clathrin-mediated and bulk endocytosis. EMBO Rep. 2016;17:47-63 pubmed 出版商
Ruiter M, Houy S, Engholm Keller K, Graham M, Sørensen J. SNAP-25 phosphorylation at Ser187 is not involved in Ca2+ or phorbolester-dependent potentiation of synaptic release. Mol Cell Neurosci. 2019;102:103452 pubmed 出版商
Lazarevic V, Mantas I, Flais I, Svenningsson P. Fluoxetine Suppresses Glutamate- and GABA-Mediated Neurotransmission by Altering SNARE Complex. Int J Mol Sci. 2019;20: pubmed 出版商
Cheng H, Chuang H. Rapid and Sensitive Nano-Immunosensors for Botulinum. ACS Sens. 2019;: pubmed 出版商
Ruiter M, Kadkova A, Scheutzow A, Malsam J, Sollner T, Sørensen J. An Electrostatic Energy Barrier for SNARE-Dependent Spontaneous and Evoked Synaptic Transmission. Cell Rep. 2019;26:2340-2352.e5 pubmed 出版商
Garland M, Babin B, Miyashita S, Loscher S, Shen Y, Dong M, et al. Covalent Modifiers of Botulinum Neurotoxin Counteract Toxin Persistence. ACS Chem Biol. 2019;14:76-87 pubmed 出版商
Maidorn M, Olichon A, Rizzoli S, Opazo F. Nanobodies reveal an extra-synaptic population of SNAP-25 and Syntaxin 1A in hippocampal neurons. MAbs. 2019;11:305-321 pubmed 出版商
Lazarevic V, Yang Y, Ivanova D, Fejtova A, Svenningsson P. Riluzole attenuates the efficacy of glutamatergic transmission by interfering with the size of the readily releasable neurotransmitter pool. Neuropharmacology. 2018;143:38-48 pubmed 出版商
Bello O, Jouannot O, Chaudhuri A, Stroeva E, Coleman J, Volynski K, et al. Synaptotagmin oligomerization is essential for calcium control of regulated exocytosis. Proc Natl Acad Sci U S A. 2018;115:E7624-E7631 pubmed 出版商
Zheng Y, Shen W, Zhang J, Yang B, Liu Y, Qi H, et al. CRISPR interference-based specific and efficient gene inactivation in the brain. Nat Neurosci. 2018;21:447-454 pubmed 出版商
Zhang S, Lebreton F, Mansfield M, Miyashita S, Zhang J, Schwartzman J, et al. Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium. Cell Host Microbe. 2018;23:169-176.e6 pubmed 出版商
Liu X, Li J, Guo C, Wang H, Sun Y, Wang H, et al. Olanzapine Reverses MK-801-Induced Cognitive Deficits and Region-Specific Alterations of NMDA Receptor Subunits. Front Behav Neurosci. 2017;11:260 pubmed 出版商
Salunkhe V, Ofori J, Gandasi N, Salö S, Hansson S, Andersson M, et al. MiR-335 overexpression impairs insulin secretion through defective priming of insulin vesicles. Physiol Rep. 2017;5: pubmed 出版商
Nakaya N, Sultana A, Tomarev S. Impaired AMPA receptor trafficking by a double knockout of zebrafish olfactomedin1a/b. J Neurochem. 2017;143:635-644 pubmed 出版商
Acuna C, Liu X, Sudhof T. How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs. Neuron. 2016;91:792-807 pubmed 出版商
Bacaj T, Wu D, Burré J, Malenka R, Liu X, Sudhof T. Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles. PLoS Biol. 2015;13:e1002267 pubmed 出版商
Koo S, Kochlamazashvili G, Rost B, Puchkov D, Gimber N, Lehmann M, et al. Vesicular Synaptobrevin/VAMP2 Levels Guarded by AP180 Control Efficient Neurotransmission. Neuron. 2015;88:330-44 pubmed 出版商
Ciani L, Marzo A, Boyle K, Stamatakou E, Lopes D, Anane D, et al. Wnt signalling tunes neurotransmitter release by directly targeting Synaptotagmin-1. Nat Commun. 2015;6:8302 pubmed 出版商
Liu Y, Li H, Sugiura Y, Han W, Gallardo G, Khvotchev M, et al. Ubiquitin-Synaptobrevin Fusion Protein Causes Degeneration of Presynaptic Motor Terminals in Mice. J Neurosci. 2015;35:11514-31 pubmed 出版商
Chang S, Reim K, Pedersen M, Neher E, Brose N, Taschenberger H. Complexin stabilizes newly primed synaptic vesicles and prevents their premature fusion at the mouse calyx of held synapse. J Neurosci. 2015;35:8272-90 pubmed 出版商
Burré J, Sharma M, Südhof T. α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation. Proc Natl Acad Sci U S A. 2014;111:E4274-83 pubmed 出版商
Wilhelm B, Mandad S, Truckenbrodt S, Kr hnert K, Sch fer C, Rammner B, et al. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Science. 2014;344:1023-8 pubmed 出版商
Liu X, Heidelberger R, Janz R. Phosphorylation of syntaxin 3B by CaMKII regulates the formation of t-SNARE complexes. Mol Cell Neurosci. 2014;60:53-62 pubmed 出版商
Kirizs T, Kerti Szigeti K, Lorincz A, Nusser Z. Distinct axo-somato-dendritic distributions of three potassium channels in CA1 hippocampal pyramidal cells. Eur J Neurosci. 2014;39:1771-83 pubmed 出版商
Vazquez Cintron E, Vakulenko M, Band P, Stanker L, Johnson E, Ichtchenko K. Atoxic derivative of botulinum neurotoxin A as a prototype molecular vehicle for targeted delivery to the neuronal cytoplasm. PLoS ONE. 2014;9:e85517 pubmed 出版商
Mohrmann R, de Wit H, Connell E, Pinheiro P, Leese C, Bruns D, et al. Synaptotagmin interaction with SNAP-25 governs vesicle docking, priming, and fusion triggering. J Neurosci. 2013;33:14417-30 pubmed 出版商
Burré J, Sharma M, Sudhof T. Systematic mutagenesis of ?-synuclein reveals distinct sequence requirements for physiological and pathological activities. J Neurosci. 2012;32:15227-42 pubmed 出版商
Kaeser Woo Y, Yang X, Sudhof T. C-terminal complexin sequence is selectively required for clamping and priming but not for Ca2+ triggering of synaptic exocytosis. J Neurosci. 2012;32:2877-85 pubmed 出版商
Malarkey E, Parpura V. Temporal characteristics of vesicular fusion in astrocytes: examination of synaptobrevin 2-laden vesicles at single vesicle resolution. J Physiol. 2011;589:4271-300 pubmed 出版商
Barth J, Zimmermann H, Volknandt W. SV31 is a Zn2+-binding synaptic vesicle protein. J Neurochem. 2011;118:558-70 pubmed 出版商
Sharma M, Burr J, S dhof T. CSP? promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity. Nat Cell Biol. 2011;13:30-9 pubmed 出版商
Yeh F, Dong M, Yao J, Tepp W, Lin G, Johnson E, et al. SV2 mediates entry of tetanus neurotoxin into central neurons. PLoS Pathog. 2010;6:e1001207 pubmed 出版商
Hoopmann P, Punge A, Barysch S, Westphal V, B ckers J, Opazo F, et al. Endosomal sorting of readily releasable synaptic vesicles. Proc Natl Acad Sci U S A. 2010;107:19055-60 pubmed 出版商
Lazzell D, Belizaire R, Thakur P, Sherry D, Janz R. SV2B regulates synaptotagmin 1 by direct interaction. J Biol Chem. 2004;279:52124-31 pubmed 出版商
Wojcik S, Rhee J, Herzog E, Sigler A, Jahn R, Takamori S, et al. An essential role for vesicular glutamate transporter 1 (VGLUT1) in postnatal development and control of quantal size. Proc Natl Acad Sci U S A. 2004;101:7158-63 pubmed
Nagy G, Reim K, Matti U, Brose N, Binz T, Rettig J, et al. Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25. Neuron. 2004;41:417-29 pubmed
产品信息
Cat. Nr. :
111 011
抗原 :
SNAP25
同义词 :
SNAP 25, SUP
宿主物种 :
小鼠
Tpye :
单克隆
形式 :
纯化IgG
细胞系 :
71.1
亚类 :
IgG1
免疫原 :
Recombinant protein corresponding to AA 1 to 206 from rat SNAP25B (UniProt Id: P60881-1)
反应物种 :
人类, 大鼠, 小鼠, 脊椎动物, 无脊椎动物, 斑马鱼
免疫印迹 :
免疫印迹
免疫沉淀 :
免疫沉淀
免疫细胞化学 :
免疫细胞化学
免疫组化P :
免疫组化-P
EM :
EM
KO :
yes
规格 :
50微克
更多信息或购买 :
公司信息
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
公司总部: 德国