产品简要
公司名称 :
Synaptic Systems
产品类型 :
抗体
产品名称 :
Munc18-1
目录 :
116 002
规格 :
200微升
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
克隆名称 :
/
反应物种 :
人类, 小鼠, 大鼠, , 斑马鱼
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 25
出版应用/物种/样品/稀释参考文献
  • 免疫印迹; 小鼠; 1:2000; 图 s6a
Wang Y, Figueiredo D, Sun X, Dong Z, Chen W, Cui W, et al. Controlling of glutamate release by neuregulin3 via inhibiting the assembly of the SNARE complex. Proc Natl Acad Sci U S A. 2018;115:2508-2513 pubmed 出版商
  • 免疫印迹; 人类
Inoue M, Hur J, Kihara T, Teranishi Y, Yamamoto N, Ishikawa T, et al. Human brain proteins showing neuron-specific interactions with γ-secretase. FEBS J. 2015;282:2587-99 pubmed 出版商
Davenport E, Szulc B, Drew J, Taylor J, Morgan T, Higgs N, et al. Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition. Cell Rep. 2019;26:2037-2051.e6 pubmed 出版商
Duan M, Yan M, Wang Q, Mao M, Su D, Sun L, et al. Overexpression of miR-1 in the heart attenuates hippocampal synaptic vesicle exocytosis by the posttranscriptional regulation of SNAP-25 through the transportation of exosomes. Cell Commun Signal. 2018;16:91 pubmed 出版商
Daraio T, Valladolid Acebes I, Brismar K, Bark C. SNAP-25a and SNAP-25b differently mediate interactions with Munc18-1 and Gβγ subunits. Neurosci Lett. 2018;674:75-80 pubmed 出版商
Orock A, Logan S, Deak F. Munc18-1 haploinsufficiency impairs learning and memory by reduced synaptic vesicular release in a model of Ohtahara syndrome. Mol Cell Neurosci. 2018;88:33-42 pubmed 出版商
Salunkhe V, Ofori J, Gandasi N, Salö S, Hansson S, Andersson M, et al. MiR-335 overexpression impairs insulin secretion through defective priming of insulin vesicles. Physiol Rep. 2017;5: pubmed 出版商
Miyamoto H, Shimohata A, Abe M, Abe T, Mazaki E, Amano K, et al. Potentiation of excitatory synaptic transmission ameliorates aggression in mice with Stxbp1 haploinsufficiency. Hum Mol Genet. 2017;26:4961-4974 pubmed 出版商
Wilhelm B, Mandad S, Truckenbrodt S, Kr hnert K, Sch fer C, Rammner B, et al. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Science. 2014;344:1023-8 pubmed 出版商
Cijsouw T, Weber J, Broeke J, Broek J, Schut D, Kroon T, et al. Munc18-1 redistributes in nerve terminals in an activity- and PKC-dependent manner. J Cell Biol. 2014;204:759-75 pubmed 出版商
Spangler S, Schmitz S, Kevenaar J, de Graaff E, de Wit H, Demmers J, et al. Liprin-?2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission. J Cell Biol. 2013;201:915-28 pubmed 出版商
Rodr guez F, Zanetti M, Mayorga L, Tomes C. Munc18-1 controls SNARE protein complex assembly during human sperm acrosomal exocytosis. J Biol Chem. 2012;287:43825-39 pubmed 出版商
Jorgacevski J, Potokar M, Grilc S, Kreft M, Liu W, Barclay J, et al. Munc18-1 tuning of vesicle merger and fusion pore properties. J Neurosci. 2011;31:9055-66 pubmed 出版商
Hellwig S, Hack I, Kowalski J, Brunne B, Jarowyj J, Unger A, et al. Role for Reelin in neurotransmitter release. J Neurosci. 2011;31:2352-60 pubmed 出版商
Ohno Y, Ishihara S, Terada R, Kikuta M, Sofue N, Kawai Y, et al. Preferential increase in the hippocampal synaptic vesicle protein 2A (SV2A) by pentylenetetrazole kindling. Biochem Biophys Res Commun. 2009;390:415-20 pubmed 出版商
Malintan N, Nguyen T, Han L, Latham C, Osborne S, Wen P, et al. Abrogating Munc18-1-SNARE complex interaction has limited impact on exocytosis in PC12 cells. J Biol Chem. 2009;284:21637-46 pubmed 出版商
Camoletto P, Vara H, Morando L, Connell E, Marletto F, Giustetto M, et al. Synaptic vesicle docking: sphingosine regulates syntaxin1 interaction with Munc18. PLoS ONE. 2009;4:e5310 pubmed 出版商
Kwok M, Holopainen J, Molday L, Foster L, Molday R. Proteomics of photoreceptor outer segments identifies a subset of SNARE and Rab proteins implicated in membrane vesicle trafficking and fusion. Mol Cell Proteomics. 2008;7:1053-66 pubmed 出版商
Gomi H, Mizutani S, Kasai K, Itohara S, Izumi T. Granuphilin molecularly docks insulin granules to the fusion machinery. J Cell Biol. 2005;171:99-109 pubmed
Olsen O, Moore K, Fukata M, Kazuta T, Trinidad J, Kauer F, et al. Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex. J Cell Biol. 2005;170:1127-34 pubmed
Kasai K, Ohara Imaizumi M, Takahashi N, Mizutani S, Zhao S, Kikuta T, et al. Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation. J Clin Invest. 2005;115:388-96 pubmed
Zhang Q, Pangrsic T, Kreft M, Krzan M, Li N, Sul J, et al. Fusion-related release of glutamate from astrocytes. J Biol Chem. 2004;279:12724-33 pubmed
Houng A, Polgar J, Reed G. Munc18-syntaxin complexes and exocytosis in human platelets. J Biol Chem. 2003;278:19627-33 pubmed
Varoqueaux F, Sigler A, Rhee J, Brose N, Enk C, Reim K, et al. Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming. Proc Natl Acad Sci U S A. 2002;99:9037-42 pubmed
Zhang W, Efanov A, Yang S, Fried G, Kolare S, Brown H, et al. Munc-18 associates with syntaxin and serves as a negative regulator of exocytosis in the pancreatic beta -cell. J Biol Chem. 2000;275:41521-7 pubmed
产品信息
Cat. Nr. :
116 002
抗原 :
Munc18-1
同义词 :
rb-Sec1, n-Sec1, p67, stxbp2, stxbp1, Munc 18-1, Munc 18-2, Munc 18-3
宿主物种 :
Tpye :
多克隆
形式 :
抗血清
免疫原 :
Synthetic peptide corresponding to AA 580 to 594 from rat Munc18-1 (UniProt Id: P61765)
反应物种 :
人类, 大鼠, 小鼠, 牛
免疫印迹 :
y
免疫沉淀 :
y
免疫细胞化学 :
y
免疫组化 :
y
免疫组化P :
y
酶联免疫吸附测定 :
y
KD :
1
规格 :
200微升
更多信息或购买 :
公司信息
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
公司总部: 德国