产品简要
公司名称 :
Synaptic Systems
产品类型 :
抗体
产品名称 :
VGAT
目录 :
131 011
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
117G4
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, proximity ligation assay
更多信息或购买 :
文章摘录数: 123
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:300; 图 7a
Frew J, Nygaard H. Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice. Acta Neuropathol Commun. 2021;9:57 pubmed 出版商
  • 免疫印迹; 大鼠; 图 5s1
Kreutzberger A, Kiessling V, Doyle C, Schenk N, Upchurch C, Elmer Dixon M, et al. Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2. elife. 2020;9: pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 4c
Granger A, Wang W, Robertson K, El Rifai M, Zanello A, Bistrong K, et al. Cortical ChAT+ neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner. elife. 2020;9: pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:1000; 图 1f
Lorenzo L, Godin A, Ferrini F, Bachand K, Plasencia Fernandez I, Labrecque S, et al. Enhancing neuronal chloride extrusion rescues α2/α3 GABAA-mediated analgesia in neuropathic pain. Nat Commun. 2020;11:869 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:200; 图 7s1a
  • 免疫细胞化学; 人类; 1:200; 图 5g
  • 免疫印迹; 人类; 1:500; 图 5i
Ghatak S, Dolatabadi N, Trudler D, Zhang X, Wu Y, Mohata M, et al. Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs isogenic controls. elife. 2019;8: pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:500; 图 2a
Collins L, Brunjes P. The mouse olfactory peduncle 4: Development of synapses, perineuronal nets, and capillaries. J Comp Neurol. 2019;: pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 5c
Pan H, Fatima M, Li A, Lee H, Cai W, Horwitz L, et al. Identification of a Spinal Circuit for Mechanical and Persistent Spontaneous Itch. Neuron. 2019;103:1135-1149.e6 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 2i
Popova D, Desai N, Blendy J, Pang Z. Synaptic regulation by OPRM1 variants in reward neurocircuitry. J Neurosci. 2019;: pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:100; 图 8d
Duan W, Guo M, Yi L, Zhang J, Bi Y, Liu Y, et al. Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice. Aging (Albany NY). 2019;11:2457-2476 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 s1h
Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, et al. Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting. Science. 2019;363: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1250; 图 3g
Chmielewska J, Kuzniewska B, Milek J, Urbanska K, Dziembowska M. Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage. Mol Neurobiol. 2019;56:2741-2759 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 4a
  • 免疫组化-石蜡切片; 人类; 1:1000; 图 7g
Dunn A, Hoffman C, Stout K, Ozawa M, Dhamsania R, Miller G. Immunochemical analysis of the expression of SV2C in mouse, macaque and human brain. Brain Res. 2019;1702:85-95 pubmed 出版商
  • proximity ligation assay; 小鼠; 1:200; 图 s14e
Trepte P, Kruse S, Kostova S, Hoffmann S, Buntru A, Tempelmeier A, et al. LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells. Mol Syst Biol. 2018;14:e8071 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 2a
Nam M, Han K, Lee J, Bae J, An H, Park S, et al. Expression of µ-Opioid Receptor in CA1 Hippocampal Astrocytes. Exp Neurobiol. 2018;27:120-128 pubmed 出版商
  • 免疫组化; 大鼠; 1:200; 图 5f
Farhan S, Nixon K, Everest M, Edwards T, Long S, Segal D, et al. Identification of a novel synaptic protein, TMTC3, involved in periventricular nodular heterotopia with intellectual disability and epilepsy. Hum Mol Genet. 2017;26:4278-4289 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6d
Larimore J, Zlatic S, Arnold M, Singleton K, Cross R, Rudolph H, et al. Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus. Front Genet. 2017;8:28 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 3b
Egashira Y, Takase M, Watanabe S, Ishida J, Fukamizu A, Kaneko R, et al. Unique pH dynamics in GABAergic synaptic vesicles illuminates the mechanism and kinetics of GABA loading. Proc Natl Acad Sci U S A. 2016;113:10702-7 pubmed 出版商
  • 免疫组化; 小鼠; 1:5000; 图 5b
Hamamoto M, Kiyokage E, Sohn J, Hioki H, Harada T, Toida K. Structural basis for cholinergic regulation of neural circuits in the mouse olfactory bulb. J Comp Neurol. 2017;525:574-591 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500
Bragina L, Bonifacino T, Bassi S, Milanese M, Bonanno G, Conti F. Differential expression of metabotropic glutamate and GABA receptors at neocortical glutamatergic and GABAergic axon terminals. Front Cell Neurosci. 2015;9:345 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 6
Aoto J, Földy C, Ilcus S, Tabuchi K, Südhof T. Distinct circuit-dependent functions of presynaptic neurexin-3 at GABAergic and glutamatergic synapses. Nat Neurosci. 2015;18:997-1007 pubmed 出版商
  • 免疫组化; 小鼠; 图 4
Blanqué A, Repetto D, Rohlmann A, Brockhaus J, Duning K, Pavenstädt H, et al. Deletion of KIBRA, protein expressed in kidney and brain, increases filopodial-like long dendritic spines in neocortical and hippocampal neurons in vivo and in vitro. Front Neuroanat. 2015;9:13 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:100; 图 s8
Saunders A, Oldenburg I, Berezovskii V, Johnson C, Kingery N, Elliott H, et al. A direct GABAergic output from the basal ganglia to frontal cortex. Nature. 2015;521:85-9 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 8E
Pérez de Sevilla Müller L, Sargoy A, Fernández Sánchez L, Rodriguez A, Liu J, Cuenca N, et al. Expression and cellular localization of the voltage-gated calcium channel α2δ3 in the rodent retina. J Comp Neurol. 2015;523:1443-60 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠
Lee J, Lee E, Lee H. Hypothalamic, feeding/arousal-related peptidergic projections to the paraventricular thalamic nucleus in the rat. Brain Res. 2015;1598:97-113 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 s4
Atasoy D, Betley J, Li W, Su H, Sertel S, Scheffer L, et al. A genetically specified connectomics approach applied to long-range feeding regulatory circuits. Nat Neurosci. 2014;17:1830-9 pubmed 出版商
van Olst L, Rodriguez Mogeda C, Picón C, Kiljan S, James R, Kamermans A, et al. Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration. Acta Neuropathol. 2021;141:881-899 pubmed 出版商
Ohta K, Suzuki S, Warita K, Sumitani K, Tenkumo C, Ozawa T, et al. The effects of early life stress on the excitatory/inhibitory balance of the medial prefrontal cortex. Behav Brain Res. 2020;379:112306 pubmed 出版商
Fossati M, Assendorp N, Gemin O, Colasse S, Dingli F, Arras G, et al. Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons. Neuron. 2019;: pubmed 出版商
Moretto E, Longatti A, Murru L, Chamma I, Sessa A, Zapata J, et al. TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering. Cell Rep. 2019;29:1130-1146.e8 pubmed 出版商
Ben Moshe H, Luz I, Liraz O, Boehm Cagan A, Salomon Zimri S, MICHAELSON D. ApoE4 Exacerbates Hippocampal Pathology Following Acute Brain Penetration Injury in Female Mice. J Mol Neurosci. 2019;: pubmed 出版商
Sun Y, Blanco Centurion C, Bendell E, Vidal Ortiz A, Luo S, Liu M. Activity dynamics of amygdala GABAergic neurons during cataplexy of narcolepsy. elife. 2019;8: pubmed 出版商
Andoh M, Shibata K, Okamoto K, Onodera J, Morishita K, Miura Y, et al. Exercise Reverses Behavioral and Synaptic Abnormalities after Maternal Inflammation. Cell Rep. 2019;27:2817-2825.e5 pubmed 出版商
Hobson B, Sims P. Critical Analysis of Particle Detection Artifacts in Synaptosome Flow Cytometry. Eneuro. 2019;6: pubmed 出版商
Rhee H, Shaib A, Rehbach K, Lee C, Seif P, Thomas C, et al. An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons. Cell Rep. 2019;27:2212-2228.e7 pubmed 出版商
Paraskevopoulou F, Herman M, Rosenmund C. Glutamatergic Innervation onto Striatal Neurons Potentiates GABAergic Synaptic Output. J Neurosci. 2019;39:4448-4460 pubmed 出版商
Grove J, Hirano A, de Los Santos J, McHugh C, Purohit S, Field G, et al. Novel hybrid action of GABA mediates inhibitory feedback in the mammalian retina. PLoS Biol. 2019;17:e3000200 pubmed 出版商
Koebis M, Urata S, Shinoda Y, Okabe S, Yamasoba T, Nakao K, et al. LAMP5 in presynaptic inhibitory terminals in the hindbrain and spinal cord: a role in startle response and auditory processing. Mol Brain. 2019;12:20 pubmed 出版商
Rotterman T, Akhter E, Lane A, Macpherson K, Garcia V, TANSEY M, et al. Spinal Motor Circuit Synaptic Plasticity after Peripheral Nerve Injury Depends on Microglia Activation and a CCR2 Mechanism. J Neurosci. 2019;39:3412-3433 pubmed 出版商
Waldvogel H, Biggins F, Singh A, Arasaratnam C, Faull R. Variable colocalisation of GABAA receptor subunits and glycine receptors on neurons in the human hypoglossal nucleus. J Chem Neuroanat. 2019;97:99-111 pubmed 出版商
Magnin E, Francavilla R, Amalyan S, Gervais E, David L, Luo X, et al. Input-Specific Synaptic Location and Function of the α5 GABAA Receptor Subunit in the Mouse CA1 Hippocampal Neurons. J Neurosci. 2019;39:788-801 pubmed 出版商
Herman M, Trimbuch T, Rosenmund C. Differential pH Dynamics in Synaptic Vesicles From Intact Glutamatergic and GABAergic Synapses. Front Synaptic Neurosci. 2018;10:44 pubmed 出版商
Irintchev M, Guntinas Lichius O, Irintchev A. Botulinum Neurotoxin Application to the Severed Femoral Nerve Modulates Spinal Synaptic Responses to Axotomy and Enhances Motor Recovery in Rats. Neural Plast. 2018;2018:7975013 pubmed 出版商
Lee S, Shin S, Zhong P, Kim H, Kim D, Kim J, et al. Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes. Nat Commun. 2018;9:3434 pubmed 出版商
Nakamura T, Sakaue F, Nasu Nishimura Y, Takeda Y, Matsuura K, Akiyama T. The Autism-Related Protein PX-RICS Mediates GABAergic Synaptic Plasticity in Hippocampal Neurons and Emotional Learning in Mice. EBioMedicine. 2018;34:189-200 pubmed 出版商
Jhang J, Lee H, Kang M, Lee H, Park H, Han J. Anterior cingulate cortex and its input to the basolateral amygdala control innate fear response. Nat Commun. 2018;9:2744 pubmed 出版商
Guirado R, Carceller H, Castillo Gomez E, Castren E, Nacher J. Automated analysis of images for molecular quantification in immunohistochemistry. Heliyon. 2018;4:e00669 pubmed 出版商
Tukker A, Wijnolts F, de Groot A, Westerink R. Human iPSC-derived neuronal models for in vitro neurotoxicity assessment. Neurotoxicology. 2018;67:215-225 pubmed 出版商
Andrés Benito P, Gelpi E, Povedano M, Santpere G, Ferrer I. Gene Expression Profile in Frontal Cortex in Sporadic Frontotemporal Lobar Degeneration-TDP. J Neuropathol Exp Neurol. 2018;77:608-627 pubmed 出版商
Tata B, Mimouni N, Barbotin A, Malone S, Loyens A, Pigny P, et al. Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood. Nat Med. 2018;24:834-846 pubmed 出版商
Zhang B, Gokce O, Hale W, Brose N, Sudhof T. Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses. J Exp Med. 2018;215:1543-1553 pubmed 出版商
Li J, Shalev Benami M, Sando R, Jiang X, Kibrom A, Wang J, et al. Structural Basis for Teneurin Function in Circuit-Wiring: A Toxin Motif at the Synapse. Cell. 2018;173:735-748.e15 pubmed 出版商
Tu J, Cao D, Li L, Cheung H, Chan W. MicroRNA profiling during directed differentiation of cortical interneurons from human-induced pluripotent stem cells. FEBS Open Bio. 2018;8:502-512 pubmed 出版商
Lavian H, Loewenstern Y, Madar R, Almog M, Bar Gad I, Okun E, et al. Dopamine receptors in the rat entopeduncular nucleus. Brain Struct Funct. 2018;223:2673-2684 pubmed 出版商
Lin T, Tan Z, Barik A, Yin D, Brudvik E, Wang H, et al. Regulation of Synapse Development by Vgat Deletion from ErbB4-Positive Interneurons. J Neurosci. 2018;38:2533-2550 pubmed 出版商
Nemes A, Ayasoufi K, Ying Z, Zhou Q, Suh H, Najm I. Growth Associated Protein 43 (GAP-43) as a Novel Target for the Diagnosis, Treatment and Prevention of Epileptogenesis. Sci Rep. 2017;7:17702 pubmed 出版商
Bar R, Boehm Cagan A, Luz I, Kleper Wall Y, Michaelson D. The effects of apolipoprotein E genotype, ?-synuclein deficiency, and sex on brain synaptic and Alzheimer's disease-related pathology. Alzheimers Dement (Amst). 2018;10:1-11 pubmed 出版商
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Castillo Gomez E, Pérez Rando M, Belles M, Gilabert Juan J, Llorens J, Carceller H, et al. Early Social Isolation Stress and Perinatal NMDA Receptor Antagonist Treatment Induce Changes in the Structure and Neurochemistry of Inhibitory Neurons of the Adult Amygdala and Prefrontal Cortex. Eneuro. 2017;4: pubmed 出版商
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Kathe C, Hutson T, McMahon S, Moon L. Intramuscular Neurotrophin-3 normalizes low threshold spinal reflexes, reduces spasms and improves mobility after bilateral corticospinal tract injury in rats. elife. 2016;5: pubmed 出版商
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Adams D, Economides J, Horton J. Co-localization of glutamic acid decarboxylase and vesicular GABA transporter in cytochrome oxidase patches of macaque striate cortex. Vis Neurosci. 2015;32:E026 pubmed 出版商
Rocco B, Lewis D, Fish K. Markedly Lower Glutamic Acid Decarboxylase 67 Protein Levels in a Subset of Boutons in Schizophrenia. Biol Psychiatry. 2016;79:1006-15 pubmed 出版商
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Chacón P, del Marco Ã, Arévalo Ã, Domínguez Giménez P, García Segura L, Rodríguez Tébar A. Cerebellin 4, a synaptic protein, enhances inhibitory activity and resistance of neurons to amyloid-β toxicity. Neurobiol Aging. 2015;36:1057-71 pubmed 出版商
Shinoda Y, Ahmed S, Ramachandran B, Bharat V, Brockelt D, Altas B, et al. BDNF enhances spontaneous and activity-dependent neurotransmitter release at excitatory terminals but not at inhibitory terminals in hippocampal neurons. Front Synaptic Neurosci. 2014;6:27 pubmed 出版商
Guseva D, Loers G, Schachner M. Function-triggering antibodies to the adhesion molecule L1 enhance recovery after injury of the adult mouse femoral nerve. PLoS ONE. 2014;9:e112984 pubmed 出版商
Demyanenko G, Mohan V, Zhang X, Brennaman L, Dharbal K, Tran T, et al. Neural cell adhesion molecule NrCAM regulates Semaphorin 3F-induced dendritic spine remodeling. J Neurosci. 2014;34:11274-87 pubmed 出版商
Spiegel I, Mardinly A, Gabel H, Bazinet J, Couch C, Tzeng C, et al. Npas4 regulates excitatory-inhibitory balance within neural circuits through cell-type-specific gene programs. Cell. 2014;157:1216-29 pubmed 出版商
Manca P, Mameli O, Caria M, Torrej n Escribano B, Blasi J. Distribution of SNAP25, VAMP1 and VAMP2 in mature and developing deep cerebellar nuclei after estrogen administration. Neuroscience. 2014;266:102-15 pubmed 出版商
del Pino I, Koch D, Schemm R, Qualmann B, Betz H, Paarmann I. Proteomic analysis of glycine receptor ? subunit (GlyR?)-interacting proteins: evidence for syndapin I regulating synaptic glycine receptors. J Biol Chem. 2014;289:11396-409 pubmed 出版商
Horváth E, Woodhams S, Nyilas R, Henstridge C, Kano M, Sakimura K, et al. Heterogeneous presynaptic distribution of monoacylglycerol lipase, a multipotent regulator of nociceptive circuits in the mouse spinal cord. Eur J Neurosci. 2014;39:419-34 pubmed 出版商
Young S, Lafourcade C, Platel J, Lin T, Bordey A. GABAergic striatal neurons project dendrites and axons into the postnatal subventricular zone leading to calcium activity. Front Cell Neurosci. 2014;8:10 pubmed 出版商
Mendoza Schulz A, Jing Z, Sánchez Caro J, Wetzel F, Dresbach T, Strenzke N, et al. Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse. EMBO J. 2014;33:512-27 pubmed 出版商
Chang C, Trimbuch T, Chao H, Jordan J, Herman M, Rosenmund C. Investigation of synapse formation and function in a glutamatergic-GABAergic two-neuron microcircuit. J Neurosci. 2014;34:855-68 pubmed 出版商
Iwabuchi S, Koh J, Wang K, Ho K, Harata N. Minimal Change in the cytoplasmic calcium dynamics in striatal GABAergic neurons of a DYT1 dystonia knock-in mouse model. PLoS ONE. 2013;8:e80793 pubmed 出版商
Puglisi F, Vanni V, Ponterio G, Tassone A, Sciamanna G, Bonsi P, et al. Torsin A Localization in the Mouse Cerebellar Synaptic Circuitry. PLoS ONE. 2013;8:e68063 pubmed 出版商
Antes R, Ezra Elia R, Weinberger D, Solomon A, Ofri R, Michaelson D. ApoE4 induces synaptic and ERG impairments in the retina of young targeted replacement apoE4 mice. PLoS ONE. 2013;8:e64949 pubmed 出版商
Xapelli S, Agasse F, Sard Arroyo L, Bernardino L, Santos T, Ribeiro F, et al. Activation of type 1 cannabinoid receptor (CB1R) promotes neurogenesis in murine subventricular zone cell cultures. PLoS ONE. 2013;8:e63529 pubmed 出版商
Crèvecoeur J, Kaminski R, Rogister B, Foerch P, Vandenplas C, Neveux M, et al. Expression pattern of synaptic vesicle protein 2 (SV2) isoforms in patients with temporal lobe epilepsy and hippocampal sclerosis. Neuropathol Appl Neurobiol. 2014;40:191-204 pubmed 出版商
Hanson J, Deng L, Hackos D, Lo S, Lauffer B, Steiner P, et al. Histone deacetylase 2 cell autonomously suppresses excitatory and enhances inhibitory synaptic function in CA1 pyramidal neurons. J Neurosci. 2013;33:5924-9 pubmed 出版商
Raslan A, Ernst P, Werle M, Thieme H, Szameit K, Finkensieper M, et al. Reduced cholinergic and glutamatergic synaptic input to regenerated motoneurons after facial nerve repair in rats: potential implications for recovery of motor function. Brain Struct Funct. 2014;219:891-909 pubmed 出版商
Murata Y, Constantine Paton M. Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway. J Neurosci. 2013;33:5040-52 pubmed 出版商
Hioki H, Okamoto S, Konno M, Kameda H, Sohn J, Kuramoto E, et al. Cell type-specific inhibitory inputs to dendritic and somatic compartments of parvalbumin-expressing neocortical interneuron. J Neurosci. 2013;33:544-55 pubmed 出版商
de Sevilla Müller L, Liu J, Solomon A, Rodriguez A, Brecha N. Expression of voltage-gated calcium channel ?(2)?(4) subunits in the mouse and rat retina. J Comp Neurol. 2013;521:2486-501 pubmed 出版商
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产品信息
Cat. Nr. :
131 011
抗原 :
VGAT
同义词 :
VIAAT, SLC32A1
宿主物种 :
小鼠
Tpye :
单克隆
形式 :
纯化IgG
细胞系 :
117G4
亚类 :
IgG3
免疫原 :
Synthetic peptide corresponding to AA 75 to 87 from rat VGAT (UniProt Id: O35458)
反应物种 :
human, rat, mouse, Guinea pig, monkey
免疫印迹 :
免疫印迹
免疫沉淀 :
免疫沉淀
免疫细胞化学 :
免疫细胞化学
免疫组化 :
免疫组化
免疫组化P :
免疫组化-P
EM :
EM
流式细胞仪 :
流式细胞仪
KO :
yes
规格 :
100微克
更多信息或购买 :
公司信息
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
公司总部: 德国