产品简要
公司名称 :
Synaptic Systems
产品类型 :
抗体
产品名称 :
Gephyrin
目录 :
147 021
规格 :
300微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
mAb7a
反应物种 :
人类, 小鼠, 大鼠, 斑马鱼
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
更多信息或购买 :
文章摘录数: 76
出版应用/物种/样本/稀释参考文献
  • 免疫组化-自由浮动切片; 小鼠; 图 s1f
Cserép C, Pósfai B, Lénárt N, Fekete R, László Z, Lele Z, et al. Microglia monitor and protect neuronal function through specialized somatic purinergic junctions. Science. 2020;367:528-537 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 9h4
Nakamoto C, Konno K, Miyazaki T, Nakatsukasa E, Natsume R, Abe M, et al. Expression mapping, quantification, and complex formation of GluD1 and GluD2 glutamate receptors in adult mouse brain. J Comp Neurol. 2019;: pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:200; 图 12j
  • 免疫细胞化学; 大鼠; 1:200; 图 8e
Miralles C, Taylor M, Bear J, Fekete C, George S, Li Y, et al. Expression of protocadherin-γC4 protein in the rat brain. J Comp Neurol. 2019;: pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 1b
Han W, Li J, Pelkey K, Pandey S, Chen X, Wang Y, et al. Shisa7 is a GABAA receptor auxiliary subunit controlling benzodiazepine actions. Science. 2019;366:246-250 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 3a
Duan J, Pandey S, Li T, Castellano D, Gu X, Li J, et al. Genetic Deletion of GABAA Receptors Reveals Distinct Requirements of Neurotransmitter Receptors for GABAergic and Glutamatergic Synapse Development. Front Cell Neurosci. 2019;13:217 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 2a
Boccalaro I, Cristiá Lara L, Schwerdel C, Fritschy J, Rubi L. Cell type-specific distribution of GABAA receptor subtypes in the mouse dorsal striatum. J Comp Neurol. 2019;527:2030-2046 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 ev3a
Fossati G, Pozzi D, Canzi A, Mirabella F, Valentino S, Morini R, et al. Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1-integrin. EMBO J. 2019;38: pubmed 出版商
  • 免疫组化; 小鼠; 图 4g
Martenson J, Yamasaki T, Chaudhury N, Albrecht D, Tomita S. Assembly rules for GABAA receptor complexes in the brain. elife. 2017;6: pubmed 出版商
  • 免疫组化; 大鼠; 1:200; 图 2d
Fekete C, Goz R, Dinallo S, Miralles C, Chiou T, Bear J, et al. In vivo transgenic expression of collybistin in neurons of the rat cerebral cortex. J Comp Neurol. 2017;525:1291-1311 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 4d
Sohn J, Okamoto S, Kataoka N, Kaneko T, Nakamura K, Hioki H. Differential Inputs to the Perisomatic and Distal-Dendritic Compartments of VIP-Positive Neurons in Layer 2/3 of the Mouse Barrel Cortex. Front Neuroanat. 2016;10:124 pubmed 出版商
  • 免疫细胞化学; 人类
Nguyen T, Schreiner D, Xiao L, Traunmüller L, Bornmann C, Scheiffele P. An alternative splicing switch shapes neurexin repertoires in principal neurons versus interneurons in the mouse hippocampus. elife. 2016;5: pubmed 出版商
  • 免疫组化; 大鼠; 1:2000; 图 s3
Ghosh H, Auguadri L, Battaglia S, Simone Thirouin Z, Zemoura K, Messner S, et al. Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission. Nat Commun. 2016;7:13365 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 3
Xia M, Zhu S, Shevelkin A, Ross C, Pletnikov M. DISC1, astrocytes and neuronal maturation: a possible mechanistic link with implications for mental disorders. J Neurochem. 2016;138:518-24 pubmed 出版商
  • 免疫组化; 大鼠; 图 5e
  • 免疫印迹; 大鼠; 图 2b
Um J, Choii G, Park D, Kim D, Jeon S, Kang H, et al. IQ Motif and SEC7 Domain-containing Protein 3 (IQSEC3) Interacts with Gephyrin to Promote Inhibitory Synapse Formation. J Biol Chem. 2016;291:10119-30 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 1
Zhang Q, Gao X, Li C, Feliciano C, Wang D, Zhou D, et al. Impaired Dendritic Development and Memory in Sorbs2 Knock-Out Mice. J Neurosci. 2016;36:2247-60 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 6
Lyons M, Chen L, Deng J, Finn C, Pfenning A, Sabhlok A, et al. The transcription factor calcium-response factor limits NMDA receptor-dependent transcription in the developing brain. J Neurochem. 2016;137:164-76 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:200
  • 免疫组化; 大鼠; 1:200
Fekete C, Chiou T, Miralles C, Harris R, Fiondella C, LoTurco J, et al. In vivo clonal overexpression of neuroligin 3 and neuroligin 2 in neurons of the rat cerebral cortex: Differential effects on GABAergic synapses and neuronal migration. J Comp Neurol. 2015;523:1359-78 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 3,4
  • 免疫细胞化学; 大鼠; 1:500; 图 6
Kang Y, Ge Y, Cassidy R, Lam V, Luo L, Moon K, et al. A combined transgenic proteomic analysis and regulated trafficking of neuroligin-2. J Biol Chem. 2014;289:29350-64 pubmed 出版商
  • 免疫细胞化学; 人类
Ohkawa T, Satake S, Yokoi N, Miyazaki Y, Ohshita T, Sobue G, et al. Identification and characterization of GABA(A) receptor autoantibodies in autoimmune encephalitis. J Neurosci. 2014;34:8151-63 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:250; 图 1
Karayannis T, Au E, Patel J, Kruglikov I, Markx S, Delorme R, et al. Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission. Nature. 2014;511:236-40 pubmed
  • 免疫组化; 大鼠; 1:500
Corteen N, Cole T, Sarna A, Sieghart W, Swinny J. Localization of GABA-A receptor alpha subunits on neurochemically distinct cell types in the rat locus coeruleus. Eur J Neurosci. 2011;34:250-62 pubmed 出版商
Halff E, Szulc B, Lesept F, Kittler J. SNX27-Mediated Recycling of Neuroligin-2 Regulates Inhibitory Signaling. Cell Rep. 2019;29:2599-2607.e6 pubmed 出版商
Lorenz Guertin J, Bambino M, Das S, Weintraub S, Jacob T. Diazepam Accelerates GABAAR Synaptic Exchange and Alters Intracellular Trafficking. Front Cell Neurosci. 2019;13:163 pubmed 出版商
Salib M, Joshi A, Katona L, Howarth M, Micklem B, Somogyi P, et al. GABAergic Medial Septal Neurons with Low-Rhythmic Firing Innervating the Dentate Gyrus and Hippocampal Area CA3. J Neurosci. 2019;39:4527-4549 pubmed 出版商
Binda C, Nakamura Y, Henley J, Wilkinson K. Sorting nexin 27 rescues neuroligin 2 from lysosomal degradation to control inhibitory synapse number. Biochem J. 2019;: pubmed 出版商
Handara G, Hetsch F, Jüttner R, Schick A, Haupt C, Rathjen F, et al. The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons. Dev Biol. 2019;445:54-67 pubmed 出版商
Wang H, Cheng K, Chen P, Tseng K, Kwan A, Chang L. Glycine receptors expression in rat spinal cord and dorsal root ganglion in prostaglandin E2 intrathecal injection models. BMC Neurosci. 2018;19:72 pubmed 出版商
Bragina L, Conti F. Expression of Neurofilament Subunits at Neocortical Glutamatergic and GABAergic Synapses. Front Neuroanat. 2018;12:74 pubmed 出版商
Zhang P, Lu H, Peixoto R, Pines M, Ge Y, Oku S, et al. Heparan Sulfate Organizes Neuronal Synapses through Neurexin Partnerships. Cell. 2018;174:1450-1464.e23 pubmed 出版商
He H, Shen W, Zheng L, Guo X, Cline H. Excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity. Nat Commun. 2018;9:2893 pubmed 出版商
Okamoto K, Hitora Imamura N, Hioki H, Ikegaya Y. GABAergic malfunction in the anterior cingulate cortex underlying maternal immune activation-induced social deficits. J Neuroimmunol. 2018;321:92-96 pubmed 出版商
Bae J, Lee J, Ko S, Cho Y, Rah J, Cho H, et al. Extrasynaptic homomeric glycine receptors in neurons of the rat trigeminal mesencephalic nucleus. Brain Struct Funct. 2018;223:2259-2268 pubmed 出版商
Koh S, Chen W, Dejneka N, Harris I, Lu B, Girman S, et al. Subretinal Human Umbilical Tissue-Derived Cell Transplantation Preserves Retinal Synaptic Connectivity and Attenuates Müller Glial Reactivity. J Neurosci. 2018;38:2923-2943 pubmed 出版商
Virtanen M, Lacoh C, Fiumelli H, Kosel M, Tyagarajan S, De Roo M, et al. Development of inhibitory synaptic inputs on layer 2/3 pyramidal neurons in the rat medial prefrontal cortex. Brain Struct Funct. 2018;223:1999-2012 pubmed 出版商
Brady M, Pilli J, Lorenz Guertin J, Das S, Moon C, Graff N, et al. Depolarizing, inhibitory GABA type A receptor activity regulates GABAergic synapse plasticity via ERK and BDNF signaling. Neuropharmacology. 2018;128:324-339 pubmed 出版商
Li J, Han W, Pelkey K, Duan J, Mao X, Wang Y, et al. Molecular Dissection of Neuroligin 2 and Slitrk3 Reveals an Essential Framework for GABAergic Synapse Development. Neuron. 2017;96:808-826.e8 pubmed 出版商
de Groot C, Floriou Servou A, Tsai Y, Früh S, Kohler M, Parkin G, et al. RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of ?2 GABAA receptors. PLoS Genet. 2017;13:e1007073 pubmed 出版商
Cantaut Belarif Y, Antri M, Pizzarelli R, Colasse S, Vaccari I, Soares S, et al. Microglia control the glycinergic but not the GABAergic synapses via prostaglandin E2 in the spinal cord. J Cell Biol. 2017;216:2979-2989 pubmed 出版商
Glebov O, Jackson R, Winterflood C, Owen D, Barker E, Doherty P, et al. Nanoscale Structural Plasticity of the Active Zone Matrix Modulates Presynaptic Function. Cell Rep. 2017;18:2715-2728 pubmed 出版商
Ripamonti S, Ambrozkiewicz M, Guzzi F, Gravati M, Biella G, Bormuth I, et al. Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons. elife. 2017;6: pubmed 出版商
Pennacchietti F, Vascon S, Nieus T, Rosillo C, Das S, Tyagarajan S, et al. Nanoscale Molecular Reorganization of the Inhibitory Postsynaptic Density Is a Determinant of GABAergic Synaptic Potentiation. J Neurosci. 2017;37:1747-1756 pubmed 出版商
Abraira V, Kuehn E, Chirila A, Springel M, Toliver A, Zimmerman A, et al. The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn. Cell. 2017;168:295-310.e19 pubmed 出版商
Früh S, Romanos J, Panzanelli P, Bürgisser D, Tyagarajan S, Campbell K, et al. Neuronal Dystroglycan Is Necessary for Formation and Maintenance of Functional CCK-Positive Basket Cell Terminals on Pyramidal Cells. J Neurosci. 2016;36:10296-10313 pubmed
Dondzillo A, Thompson J, Klug A. Recurrent Inhibition to the Medial Nucleus of the Trapezoid Body in the Mongolian Gerbil (Meriones Unguiculatus). PLoS ONE. 2016;11:e0160241 pubmed 出版商
Gutierrez Mecinas M, Kuehn E, Abraira V, Polgár E, Watanabe M, Todd A. Immunostaining for Homer reveals the majority of excitatory synapses in laminae I-III of the mouse spinal dorsal horn. Neuroscience. 2016;329:171-81 pubmed 出版商
Terauchi A, Johnson Venkatesh E, Bullock B, Lehtinen M, Umemori H. Retrograde fibroblast growth factor 22 (FGF22) signaling regulates insulin-like growth factor 2 (IGF2) expression for activity-dependent synapse stabilization in the mammalian brain. elife. 2016;5: pubmed 出版商
Nakamura Y, Morrow D, Modgil A, Huyghe D, Deeb T, Lumb M, et al. Proteomic Characterization of Inhibitory Synapses Using a Novel pHluorin-tagged ?-Aminobutyric Acid Receptor, Type A (GABAA), ?2 Subunit Knock-in Mouse. J Biol Chem. 2016;291:12394-407 pubmed 出版商
O Sullivan G, Jedlicka P, Chen H, Kalbouneh H, Ippolito A, Deller T, et al. Forebrain-specific loss of synaptic GABAA receptors results in altered neuronal excitability and synaptic plasticity in mice. Mol Cell Neurosci. 2016;72:101-13 pubmed 出版商
Lenz M, Galanis C, Müller Dahlhaus F, Opitz A, Wierenga C, Szabó G, et al. Repetitive magnetic stimulation induces plasticity of inhibitory synapses. Nat Commun. 2016;7:10020 pubmed 出版商
Saito A, Taniguchi Y, Rannals M, Merfeld E, Ballinger M, Koga M, et al. Early postnatal GABAA receptor modulation reverses deficits in neuronal maturation in a conditional neurodevelopmental mouse model of DISC1. Mol Psychiatry. 2016;21:1449-59 pubmed 出版商
Bhagat S, Butler S, Taylor J, McEwen B, Strittmatter S. Erasure of fear memories is prevented by Nogo Receptor 1 in adulthood. Mol Psychiatry. 2016;21:1281-9 pubmed 出版商
Vullhorst D, Mitchell R, Keating C, Roychowdhury S, Karavanova I, Tao Cheng J, et al. A negative feedback loop controls NMDA receptor function in cortical interneurons via neuregulin 2/ErbB4 signalling. Nat Commun. 2015;6:7222 pubmed 出版商
Hausrat T, Muhia M, Gerrow K, Thomas P, Hirdes W, Tsukita S, et al. Radixin regulates synaptic GABAA receptor density and is essential for reversal learning and short-term memory. Nat Commun. 2015;6:6872 pubmed 出版商
Fidzinski P, Korotkova T, Heidenreich M, Maier N, Schuetze S, Kobler O, et al. KCNQ5 K(+) channels control hippocampal synaptic inhibition and fast network oscillations. Nat Commun. 2015;6:6254 pubmed 出版商
Flores C, Nikonenko I, Mendez P, Fritschy J, Tyagarajan S, Muller D. Activity-dependent inhibitory synapse remodeling through gephyrin phosphorylation. Proc Natl Acad Sci U S A. 2015;112:E65-72 pubmed 出版商
Antonelli R, Pizzarelli R, Pedroni A, Fritschy J, Del Sal G, Cherubini E, et al. Pin1-dependent signalling negatively affects GABAergic transmission by modulating neuroligin2/gephyrin interaction. Nat Commun. 2014;5:5066 pubmed 出版商
Petrini E, Ravasenga T, Hausrat T, Iurilli G, Olcese U, Racine V, et al. Synaptic recruitment of gephyrin regulates surface GABAA receptor dynamics for the expression of inhibitory LTP. Nat Commun. 2014;5:3921 pubmed 出版商
Mendoza Schulz A, Jing Z, Sánchez Caro J, Wetzel F, Dresbach T, Strenzke N, et al. Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse. EMBO J. 2014;33:512-27 pubmed 出版商
Notter T, Panzanelli P, PFISTER S, Mircsof D, Fritschy J. A protocol for concurrent high-quality immunohistochemical and biochemical analyses in adult mouse central nervous system. Eur J Neurosci. 2014;39:165-75 pubmed 出版商
Chugh D, Nilsson P, Afjei S, Bakochi A, Ekdahl C. Brain inflammation induces post-synaptic changes during early synapse formation in adult-born hippocampal neurons. Exp Neurol. 2013;250:176-88 pubmed 出版商
Ganser L, Yan Q, James V, Kozol R, Topf M, Harvey R, et al. Distinct phenotypes in zebrafish models of human startle disease. Neurobiol Dis. 2013;60:139-51 pubmed 出版商
Linsalata A, Chen X, Winters C, Reese T. Electron tomography on γ-aminobutyric acid-ergic synapses reveals a discontinuous postsynaptic network of filaments. J Comp Neurol. 2014;522:921-36 pubmed 出版商
Stephan A, Madison D, Mateos J, Fraser D, Lovelett E, Coutellier L, et al. A dramatic increase of C1q protein in the CNS during normal aging. J Neurosci. 2013;33:13460-74 pubmed 出版商
Bleckert A, Parker E, Kang Y, Pancaroglu R, Soto F, Lewis R, et al. Spatial relationships between GABAergic and glutamatergic synapses on the dendrites of distinct types of mouse retinal ganglion cells across development. PLoS ONE. 2013;8:e69612 pubmed 出版商
Martinez Cue C, Martinez P, Rueda N, Vidal R, Garcia S, Vidal V, et al. Reducing GABAA ?5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome. J Neurosci. 2013;33:3953-66 pubmed 出版商
Pettem K, Yokomaku D, Takahashi H, Ge Y, Craig A. Interaction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse development. J Cell Biol. 2013;200:321-36 pubmed 出版商
Hughes D, Boyle K, Kinnon C, Bilsland C, Quayle J, Callister R, et al. HCN4 subunit expression in fast-spiking interneurons of the rat spinal cord and hippocampus. Neuroscience. 2013;237:7-18 pubmed 出版商
Li Y, Xiao H, Chiou T, Jin H, Bonhomme B, Miralles C, et al. Molecular and functional interaction between protocadherin-?C5 and GABAA receptors. J Neurosci. 2012;32:11780-97 pubmed 出版商
Abbott C, Percival K, Martin P, Grünert U. Amacrine and bipolar inputs to midget and parasol ganglion cells in marmoset retina. Vis Neurosci. 2012;29:157-68 pubmed 出版商
Jackson J, Chugh D, Nilsson P, Wood J, Carlström K, Lindvall O, et al. Altered synaptic properties during integration of adult-born hippocampal neurons following a seizure insult. PLoS ONE. 2012;7:e35557 pubmed 出版商
Soto F, Bleckert A, Lewis R, Kang Y, Kerschensteiner D, Craig A, et al. Coordinated increase in inhibitory and excitatory synapses onto retinal ganglion cells during development. Neural Dev. 2011;6:31 pubmed 出版商
Hua Y, Sinha R, Thiel C, Schmidt R, Hüve J, Martens H, et al. A readily retrievable pool of synaptic vesicles. Nat Neurosci. 2011;14:833-9 pubmed 出版商
Aroeira R, Ribeiro J, Sebastião A, Valente C. Age-related changes of glycine receptor at the rat hippocampus: from the embryo to the adult. J Neurochem. 2011;118:339-53 pubmed 出版商
Takahashi H, Arstikaitis P, Prasad T, Bartlett T, Wang Y, Murphy T, et al. Postsynaptic TrkC and presynaptic PTP? function as a bidirectional excitatory synaptic organizing complex. Neuron. 2011;69:287-303 pubmed 出版商
Suh Y, Terashima A, Petralia R, Wenthold R, Isaac J, Roche K, et al. A neuronal role for SNAP-23 in postsynaptic glutamate receptor trafficking. Nat Neurosci. 2010;13:338-43 pubmed 出版商
Kumar S, Buckmaster P. Hyperexcitability, interneurons, and loss of GABAergic synapses in entorhinal cortex in a model of temporal lobe epilepsy. J Neurosci. 2006;26:4613-23 pubmed
产品信息
Cat. Nr. :
147 021
抗原 :
Gephyrin
同义词 :
Gphn
宿主物种 :
小鼠
Tpye :
单克隆
形式 :
hybridoma supernatant
细胞系 :
mAb7a
亚类 :
IgG1
免疫原 :
Native Protein corresponding to AA 1 to 768 from rat Gephyrin (UniProt Id: Q03555)
反应物种 :
human, rat, mouse, pig, goldfish, zebrafish, frog
免疫细胞化学 :
免疫细胞化学
免疫组化 :
免疫组化
EM :
EM
KO :
yes
规格 :
300微升
更多信息或购买 :
公司信息
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
公司总部: 德国