产品简要
公司名称 :
Synaptic Systems
产品类型 :
抗体
产品名称 :
微管相关蛋白2
目录 :
188 004
规格 :
100微升
克隆性 :
多克隆
宿主 :
豚鼠
共轭标签 :
未共轭
克隆名称 :
/
反应物种 :
人类, 小鼠, brown rat
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 64
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 人类; 1:10,000; 图 s1d
Trevino A, Sinnott Armstrong N, Andersen J, Yoon S, Huber N, Pritchard J, et al. Chromatin accessibility dynamics in a model of human forebrain development. Science. 2020;367: pubmed 出版商
  • 免疫细胞化学; brown rat; 1:500; 图 3c
Rademacher N, Kuropka B, Kunde S, Wahl M, Freund C, Shoichet S. Intramolecular domain dynamics regulate synaptic MAGUK protein interactions. elife. 2019;8: pubmed 出版商
  • 免疫细胞化学; brown rat; 图 1c
Rangaraju V, Lauterbach M, Schuman E. Spatially Stable Mitochondrial Compartments Fuel Local Translation during Plasticity. Cell. 2019;176:73-84.e15 pubmed 出版商
  • 免疫组化; brown rat; 1:500; 图 2a
Wigerius M, Quinn D, Diab A, Clattenburg L, Kolar A, Qi J, et al. The polarity protein Angiomotin p130 controls dendritic spine maturation. J Cell Biol. 2018;217:715-730 pubmed 出版商
  • 免疫组化; 人类; 1:1000; 图 1c
Birey F, Andersen J, Makinson C, Islam S, Wei W, Huber N, et al. Assembly of functionally integrated human forebrain spheroids. Nature. 2017;545:54-59 pubmed 出版商
  • 免疫细胞化学; brown rat; 图 1b
Rademacher N, Schmerl B, Lardong J, Wahl M, Shoichet S. MPP2 is a postsynaptic MAGUK scaffold protein that links SynCAM1 cell adhesion molecules to core components of the postsynaptic density. Sci Rep. 2016;6:35283 pubmed 出版商
  • 免疫细胞化学; 人类; 1:250; 图 3a,3b
Sun Y, Paşca S, Portmann T, Goold C, Worringer K, Guan W, et al. A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients. elife. 2016;5: pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 s5
Brahic M, Bousset L, Bieri G, Melki R, Gitler A. Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1. Acta Neuropathol. 2016;131:539-48 pubmed 出版商
Tonazzini I, van Woerden G, Masciullo C, Mientjes E, Elgersma Y, Cecchini M. The role of ubiquitin ligase E3A in polarized contact guidance and rescue strategies in UBE3A-deficient hippocampal neurons. Mol Autism. 2019;10:41 pubmed 出版商
Lu X, Yang M, Yang Y, Wang X. Atlastin-1 modulates seizure activity and neuronal excitability. CNS Neurosci Ther. 2019;: pubmed 出版商
Lu C, Sanjana N. Generation of a knock-in MAP2-tdTomato reporter human embryonic stem cell line with inducible expression of NEUROG2/1 (NYGCe001-A). Stem Cell Res. 2019;41:101643 pubmed 出版商
Urban I, Kerimoglu C, Sakib M, Wang H, Benito E, Thaller C, et al. TIP60/KAT5 is required for neuronal viability in hippocampal CA1. Sci Rep. 2019;9:16173 pubmed 出版商
Frega M, Linda K, Keller J, Gümüş Akay G, Mossink B, Van Rhijn J, et al. Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling. Nat Commun. 2019;10:4928 pubmed 出版商
Böger C, Hafner A, Schlichthärle T, Strauss M, Malkusch S, Endesfelder U, et al. Super-resolution imaging and estimation of protein copy numbers at single synapses with DNA-point accumulation for imaging in nanoscale topography. Neurophotonics. 2019;6:035008 pubmed 出版商
Yang Q, Huang Z, Luo Y, Zheng F, Hu Y, Liu H, et al. Inhibition of Nwd1 activity attenuates neuronal hyperexcitability and GluN2B phosphorylation in the hippocampus. EBioMedicine. 2019;47:470-483 pubmed 出版商
Fonkeu Y, Kraynyukova N, Hafner A, Kochen L, Sartori F, Schuman E, et al. How mRNA Localization and Protein Synthesis Sites Influence Dendritic Protein Distribution and Dynamics. Neuron. 2019;103:1109-1122.e7 pubmed 出版商
Heumüller M, Glock C, Rangaraju V, Biever A, Schuman E. A genetically encodable cell-type-specific protein synthesis inhibitor. Nat Methods. 2019;16:699-702 pubmed 出版商
Deshpande D, Higelin J, Schoen M, Vomhof T, Boeckers T, Demestre M, et al. Synaptic FUS Localization During Motoneuron Development and Its Accumulation in Human ALS Synapses. Front Cell Neurosci. 2019;13:256 pubmed 出版商
Vullhorst D, Buonanno A. NMDA Receptors Regulate Neuregulin 2 Binding to ER-PM Junctions and Ectodomain Release. Mol Neurobiol. 2019;: pubmed 出版商
Avagliano Trezza R, Sonzogni M, Bossuyt S, Zampeta F, Punt A, van den Berg M, et al. Loss of nuclear UBE3A causes electrophysiological and behavioral deficits in mice and is associated with Angelman syndrome. Nat Neurosci. 2019;: pubmed 出版商
Sridharan B, Hubbs C, Llamosas N, Kilinc M, Singhera F, Willems E, et al. A Simple Procedure for Creating Scalable Phenotypic Screening Assays in Human Neurons. Sci Rep. 2019;9:9000 pubmed 出版商
Ivankovic D, Drew J, Lesept F, White I, López Doménech G, Tooze S, et al. Axonal autophagosome maturation defect through failure of ATG9A sorting underpins pathology in AP-4 deficiency syndrome. Autophagy. 2019;:1-17 pubmed 出版商
Moore S, Alsop E, Lorenzini I, Starr A, Rabichow B, Mendez E, et al. ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD. Acta Neuropathol. 2019;138:49-65 pubmed 出版商
Bieri G, Brahic M, Bousset L, Couthouis J, Kramer N, Ma R, et al. LRRK2 modifies α-syn pathology and spread in mouse models and human neurons. Acta Neuropathol. 2019;137:961-980 pubmed 出版商
Mockett B, Guevremont D, Elder M, Parfitt K, Peppercorn K, Morrissey J, et al. Glutamate Receptor Trafficking and Protein Synthesis Mediate the Facilitation of LTP by Secreted Amyloid Precursor Protein-Alpha. J Neurosci. 2019;39:3188-3203 pubmed 出版商
Walter S, Jumpertz T, Hüttenrauch M, Ogorek I, Gerber H, Storck S, et al. The metalloprotease ADAMTS4 generates N-truncated Aβ4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's disease. Acta Neuropathol. 2019;137:239-257 pubmed 出版商
Murao N, Matsubara S, Matsuda T, Noguchi H, Mutoh T, Mutoh M, et al. Np95/Uhrf1 regulates tumor suppressor gene expression of neural stem/precursor cells, contributing to neurogenesis in the adult mouse brain. Neurosci Res. 2019;143:31-43 pubmed 出版商
Bieri G, Lucin K, O Brien C, Zhang H, Villeda S, Wyss Coray T. Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration. Mol Neurodegener. 2018;13:68 pubmed 出版商
Swarnkar S, Avchalumov Y, Raveendra B, Grinman E, Puthanveettil S. Kinesin Family of Proteins Kif11 and Kif21B Act as Inhibitory Constraints of Excitatory Synaptic Transmission Through Distinct Mechanisms. Sci Rep. 2018;8:17419 pubmed 出版商
Yang Y, Tian X, Xu D, Zheng F, Lu X, Zhang Y, et al. GPR40 modulates epileptic seizure and NMDA receptor function. Sci Adv. 2018;4:eaau2357 pubmed 出版商
Elamri I, Heumüller M, Herzig L, Stirnal E, Wachtveitl J, Schuman E, et al. A New Photocaged Puromycin for an Efficient Labeling of Newly Translated Proteins in Living Neurons. Chembiochem. 2018;19:2458-2464 pubmed 出版商
Schmidt T, Ghaffarian N, Philippot C, Seifert G, Steinhäuser C, Pape H, et al. Differential regulation of chloride homeostasis and GABAergic transmission in the thalamus. Sci Rep. 2018;8:13929 pubmed 出版商
Proietti Onori M, Koopal B, Everman D, Worthington J, Jones J, Ploeg M, et al. The intellectual disability-associated CAMK2G p.Arg292Pro mutation acts as a pathogenic gain-of-function. Hum Mutat. 2018;39:2008-2024 pubmed 出版商
Heisler F, Pechmann Y, Wieser I, Altmeppen H, Veenendaal L, Muhia M, et al. Muskelin Coordinates PrPC Lysosome versus Exosome Targeting and Impacts Prion Disease Progression. Neuron. 2018;99:1155-1169.e9 pubmed 出版商
Yang Q, Zheng F, Hu Y, Yang Y, Li Y, Chen G, et al. ZDHHC8 critically regulates seizure susceptibility in epilepsy. Cell Death Dis. 2018;9:795 pubmed 出版商
Lieb A, Qiu Y, Dixon C, Heller J, Walker M, Schorge S, et al. Biochemical autoregulatory gene therapy for focal epilepsy. Nat Med. 2018;24:1324-1329 pubmed 出版商
Lee S, Lee E, Kim R, Kim J, Lee S, Park H, et al. Shank2 Deletion in Parvalbumin Neurons Leads to Moderate Hyperactivity, Enhanced Self-Grooming and Suppressed Seizure Susceptibility in Mice. Front Mol Neurosci. 2018;11:209 pubmed 出版商
Dörrbaum A, Kochen L, Langer J, Schuman E. Local and global influences on protein turnover in neurons and glia. elife. 2018;7: pubmed 出版商
Chia P, Zhong F, Niwa S, Bonnard C, Utami K, Zeng R, et al. A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability. elife. 2018;7: pubmed 出版商
Nakashima H, Tsujimura K, Irie K, Ishizu M, Pan M, Kameda T, et al. Canonical TGF-? Signaling Negatively Regulates Neuronal Morphogenesis through TGIF/Smad Complex-Mediated CRMP2 Suppression. J Neurosci. 2018;38:4791-4810 pubmed 出版商
Tushev G, Glock C, Heumüller M, Biever A, Jovanovic M, Schuman E. Alternative 3' UTRs Modify the Localization, Regulatory Potential, Stability, and Plasticity of mRNAs in Neuronal Compartments. Neuron. 2018;98:495-511.e6 pubmed 出版商
Zhang K, Daigle J, Cunningham K, Coyne A, Ruan K, Grima J, et al. Stress Granule Assembly Disrupts Nucleocytoplasmic Transport. Cell. 2018;173:958-971.e17 pubmed 出版商
Amin H, Dipalo M, De Angelis F, Berdondini L. Biofunctionalized 3D Nanopillar Arrays Fostering Cell Guidance and Promoting Synapse Stability and Neuronal Activity in Networks. ACS Appl Mater Interfaces. 2018;10:15207-15215 pubmed 出版商
Stamou M, Grodzki A, van Oostrum M, Wollscheid B, Lein P. Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex. J Neuroinflammation. 2018;15:7 pubmed 出版商
Kankowski S, Förstera B, Winkelmann A, Knauff P, Wanker E, You X, et al. A Novel RNA Editing Sensor Tool and a Specific Agonist Determine Neuronal Protein Expression of RNA-Edited Glycine Receptors and Identify a Genomic APOBEC1 Dimorphism as a New Genetic Risk Factor of Epilepsy. Front Mol Neurosci. 2017;10:439 pubmed 出版商
Krencik R, Seo K, van Asperen J, Basu N, Cvetkovic C, Barlas S, et al. Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes. Stem Cell Reports. 2017;9:1745-1753 pubmed 出版商
Höfflin F, Jack A, Riedel C, Mack Bucher J, Roos J, Corcelli C, et al. Heterogeneity of the Axon Initial Segment in Interneurons and Pyramidal Cells of Rodent Visual Cortex. Front Cell Neurosci. 2017;11:332 pubmed 出版商
Riemann D, Wallrafen R, Dresbach T. The Kohlschütter-Tönz syndrome associated gene Rogdi encodes a novel presynaptic protein. Sci Rep. 2017;7:15791 pubmed 出版商
Amin H, Marinaro F, De Pietri Tonelli D, Berdondini L. Developmental excitatory-to-inhibitory GABA-polarity switch is disrupted in 22q11.2 deletion syndrome: a potential target for clinical therapeutics. Sci Rep. 2017;7:15752 pubmed 出版商
Kury S, van Woerden G, Besnard T, Proietti Onori M, Latypova X, Towne M, et al. De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability. Am J Hum Genet. 2017;101:768-788 pubmed 出版商
Zappulo A, van den Bruck D, Ciolli Mattioli C, Franke V, Imami K, McShane E, et al. RNA localization is a key determinant of neurite-enriched proteome. Nat Commun. 2017;8:583 pubmed 出版商
Han B, Zhou R, Xia C, Zhuang X. Structural organization of the actin-spectrin-based membrane skeleton in dendrites and soma of neurons. Proc Natl Acad Sci U S A. 2017;114:E6678-E6685 pubmed 出版商
Amin H, Nieus T, Lonardoni D, Maccione A, Berdondini L. High-resolution bioelectrical imaging of Aβ-induced network dysfunction on CMOS-MEAs for neurotoxicity and rescue studies. Sci Rep. 2017;7:2460 pubmed 出版商
Gumy L, Katrukha E, Grigoriev I, Jaarsma D, Kapitein L, Akhmanova A, et al. MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus KIF5-Dependent Cargo Transport in Sensory Neurons. Neuron. 2017;94:347-362.e7 pubmed 出版商
Grima J, Daigle J, Arbez N, Cunningham K, Zhang K, Ochaba J, et al. Mutant Huntingtin Disrupts the Nuclear Pore Complex. Neuron. 2017;94:93-107.e6 pubmed 出版商
Altmüller F, Pothula S, Annamneedi A, Nakhaei Rad S, Montenegro Venegas C, Pina Fernández E, et al. Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy. PLoS Genet. 2017;13:e1006684 pubmed 出版商
Soykan T, Kaempf N, Sakaba T, Vollweiter D, Goerdeler F, Puchkov D, et al. Synaptic Vesicle Endocytosis Occurs on Multiple Timescales and Is Mediated by Formin-Dependent Actin Assembly. Neuron. 2017;93:854-866.e4 pubmed 出版商
Quinn D, Kolar A, Wigerius M, Gomm Kolisko R, Atwi H, Fawcett J, et al. Pan-neurexin perturbation results in compromised synapse stability and a reduction in readily releasable synaptic vesicle pool size. Sci Rep. 2017;7:42920 pubmed 出版商
Lam R, Töpfer F, Wood P, Busskamp V, Bamberg E. Functional Maturation of Human Stem Cell-Derived Neurons in Long-Term Cultures. PLoS ONE. 2017;12:e0169506 pubmed 出版商
Sun Q, Weinger J, Mao F, Liu G. Regulation of structural and functional synapse density by L-threonate through modulation of intraneuronal magnesium concentration. Neuropharmacology. 2016;108:426-39 pubmed 出版商
Amin H, Maccione A, Marinaro F, Zordan S, Nieus T, Berdondini L. Electrical Responses and Spontaneous Activity of Human iPS-Derived Neuronal Networks Characterized for 3-month Culture with 4096-Electrode Arrays. Front Neurosci. 2016;10:121 pubmed 出版商
Knackstedt L, Schwendt M. mGlu5 Receptors and Relapse to Cocaine-Seeking: The Role of Receptor Trafficking in Postrelapse Extinction Learning Deficits. Neural Plast. 2016;2016:9312508 pubmed 出版商
Deverman B, Pravdo P, Simpson B, Kumar S, Chan K, Banerjee A, et al. Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain. Nat Biotechnol. 2016;34:204-9 pubmed 出版商
Katsurabayashi S, Kawano H, Ii M, Nakano S, Tatsumi C, Kubota K, et al. Overexpression of Swedish mutant APP in aged astrocytes attenuates excitatory synaptic transmission. Physiol Rep. 2016;4: pubmed 出版商
产品信息
Cat. Nr. :
188 004
抗原 :
微管相关蛋白2
同义词 :
地图2, MAPT
宿主物种 :
豚鼠
Tpye :
多克隆
形式 :
抗血清
免疫原 :
Recombinant protein corresponding to AA 2 to 314 from human MAP2-4 hu (UniProt Id: P11137-4)
反应物种 :
人类, 大鼠, 小鼠
免疫印迹 :
免疫印迹
免疫细胞化学 :
免疫细胞化学
免疫组化 :
免疫组化
免疫组化P :
免疫组化-P
规格 :
100微升
更多信息或购买 :
公司信息
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
公司总部: 德国