产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
W-7 hydrochloride
目录 :
0369/100
规格 :
100毫克
价格 :
189美元
更多信息或购买 :
文章摘录数: 16
参考文献
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Schiff L, Boles N, Fernandes M, Nachmani B, Gentile R, Blenkinsop T. P38 inhibition reverses TGFβ1 and TNFα-induced contraction in a model of proliferative vitreoretinopathy. Commun Biol. 2019;2:162 pubmed 出版商
Haag N, Schüler S, Nietzsche S, Hübner C, Strenzke N, Qualmann B, et al. The Actin Nucleator Cobl Is Critical for Centriolar Positioning, Postnatal Planar Cell Polarity Refinement, and Function of the Cochlea. Cell Rep. 2018;24:2418-2431.e6 pubmed 出版商
Yanda M, Liu Q, Cebotaru V, Guggino W, Cebotaru L. Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca2+ in knock-out mouse models of polycystic kidney disease. J Biol Chem. 2017;292:17897-17908 pubmed 出版商
Gray M, Golowasch J. Voltage Dependence of a Neuromodulator-Activated Ionic Current. Eneuro. 2016;3: pubmed 出版商
Hou W, Izadi M, Nemitz S, Haag N, Kessels M, Qualmann B. The Actin Nucleator Cobl Is Controlled by Calcium and Calmodulin. PLoS Biol. 2015;13:e1002233 pubmed 出版商
Yuan G, Vasavda C, Peng Y, Makarenko V, Raghuraman G, Nanduri J, et al. Protein kinase G-regulated production of H2S governs oxygen sensing. Sci Signal. 2015;8:ra37 pubmed 出版商
Bonnefond M, Lambert B, Giffard F, Abeilard E, Brotin E, Louis M, et al. Calcium signals inhibition sensitizes ovarian carcinoma cells to anti-Bcl-xL strategies through Mcl-1 down-regulation. Apoptosis. 2015;20:535-50 pubmed 出版商
Araki Y, Zeng M, Zhang M, Huganir R. Rapid dispersion of SynGAP from synaptic spines triggers AMPA receptor insertion and spine enlargement during LTP. Neuron. 2015;85:173-89 pubmed 出版商
Mukunda L, Lavista Llanos S, Hansson B, Wicher D. Dimerisation of the Drosophila odorant coreceptor Orco. Front Cell Neurosci. 2014;8:261 pubmed 出版商
Chang M, Lin L, Wu H, Ho Y, Hsien H, Wang T, et al. Areca nut-induced buccal mucosa fibroblast contraction and its signaling: a potential role in oral submucous fibrosis--a precancer condition. Carcinogenesis. 2013;34:1096-104 pubmed 出版商
Abdou H, Villeneuve G, Tremblay J. The calcium signaling pathway regulates leydig cell steroidogenesis through a transcriptional cascade involving the nuclear receptor NR4A1 and the steroidogenic acute regulatory protein. Endocrinology. 2013;154:511-20 pubmed 出版商
Midkiff J, Borochoff Porte N, White D, Johnson D. Small molecule inhibitors of the Candida albicans budded-to-hyphal transition act through multiple signaling pathways. PLoS ONE. 2011;6:e25395 pubmed 出版商
Dai Y, Dudek N, Li Q, Muma N. Phospholipase C, Ca2+, and calmodulin signaling are required for 5-HT2A receptor-mediated transamidation of Rac1 by transglutaminase. Psychopharmacology (Berl). 2011;213:403-12 pubmed 出版商
Yanes L, Romero D. Dihydrotestosterone stimulates aldosterone secretion by H295R human adrenocortical cells. Mol Cell Endocrinol. 2009;303:50-6 pubmed 出版商
Long P, Mercer A, Begum R, Stephens G, Sihra T, Jovanovic J. Nerve Terminal GABAA Receptors Activate Ca2+/Calmodulin-dependent Signaling to Inhibit Voltage-gated Ca2+ Influx and Glutamate Release. J Biol Chem. 2009;284:8726-37 pubmed 出版商
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
0369
SKU号 :
0369/100
产品名称 :
W-7 hydrochloride
描述 :
Calmodulin antagonist. Inhibits myosin light chain kinase
靶标 :
Calcium Binding Protein Modulator Antagonists
类别 :
Small Molecules
单位尺寸 :
100毫克
纯度 :
98%
观察到的分子量 :
377.33
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
W-7 hydrochloride is a calmodulin antagonist. Inhibits Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 28 M) and myosin light chain kinase (IC50 = 51 M).
extended description :
Calmodulin antagonist. Inhibits myosin light chain kinase
化学品名文本 :
N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride
配方 :
C 16 H 21 ClN 2 O 2 S.HCl
配方文本 :
C16H21ClN2O2S.氯化氢
cas num :
61714-27-0
美元 :
189美元
产品细节 :
Calmodulin antagonist. Inhibits myosin light chain kinase
储存 :
存放在RT
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国