产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
Anpirtoline hydrochloride
目录 :
0703/10
规格 :
10 mg (also 50 mg)
价格 :
225美元
更多信息或购买 :
文章摘录数: 3
参考文献
Gadgaard C, Jensen A. Functional characterization of 5-HT1A and 5-HT1B serotonin receptor signaling through G-protein-activated inwardly rectifying K+ channels in a fluorescence-based membrane potential assay. Biochem Pharmacol. 2020;175:113870 pubmed 出版商
Carvalho Dias E, Miranda A, Martinho O, Mota P, Costa A, Nogueira Silva C, et al. Serotonin regulates prostate growth through androgen receptor modulation. Sci Rep. 2017;7:15428 pubmed 出版商
Müller T, Dürk T, Blumenthal B, Grimm M, Cicko S, Panther E, et al. 5-hydroxytryptamine modulates migration, cytokine and chemokine release and T-cell priming capacity of dendritic cells in vitro and in vivo. PLoS ONE. 2009;4:e6453 pubmed 出版商
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
0703
SKU号 :
0703/10
产品名称 :
Anpirtoline hydrochloride
描述 :
Highly potent 5-HT1B agonist; also 5-HT3 antagonist
靶标 :
5-HT1B Receptor Agonists
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
99%
观察到的分子量 :
265.2
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
Anpirtoline hydrochloride is a highly potent 5-HT1B receptor agonist (Ki values are 28, 150 and 1490 nM at 5-HT1B, 5-HT1A and 5-HT2 receptors respectively). Decreases central serotonin synthesis and attenuates aggressive behavior in vivo . Also acts as an antagonist at 5-HT3 receptors (Ki = 29.5 nM) and is brain penetrant.
extended description :
Highly potent 5-HT1B agonist; also 5-HT3 antagonist
化学品名文本 :
6-Chloro-2-[piperidinyl-4-thio]pyridine hydrochloride
配方 :
C 10 H 13 ClN 2 S.HCl
配方文本 :
C10H13ClN2S.氯化氢
cas num :
99201-87-3
美元 :
225美元
产品细节 :
Highly potent 5-HT1B agonist; also 5-HT3 antagonist
储存 :
Desiccate at +4°C
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国