产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
盐酸氟西汀
目录 :
0927/10
规格 :
10 mg (also 50 mg)
价格 :
122美元
更多信息或购买 :
文章摘录数: 10
参考文献
Kant R, Pasi S, Surolia A. Auto-Reactive Th17-Cells Trigger Obsessive-Compulsive-Disorder Like Behavior in Mice With Experimental Autoimmune Encephalomyelitis. Front Immunol. 2018;9:2508 pubmed 出版商
Zhang X, Gaudry Q. Functional integration of a serotonergic neuron in the Drosophila antennal lobe. elife. 2016;5: pubmed 出版商
Hooper C, Delaney C, Streeter T, Yarboro M, Poole S, Brown N, et al. Selective serotonin reuptake inhibitor exposure constricts the mouse ductus arteriosus in utero. Am J Physiol Heart Circ Physiol. 2016;311:H572-81 pubmed 出版商
Sallin P, Jazwinska A. Acute stress is detrimental to heart regeneration in zebrafish. Open Biol. 2016;6: pubmed 出版商
Pai V, Lemire J, Paré J, Lin G, Chen Y, Levin M. Endogenous gradients of resting potential instructively pattern embryonic neural tissue via Notch signaling and regulation of proliferation. J Neurosci. 2015;35:4366-85 pubmed 出版商
Silva B, Goles N, Varas R, Campusano J. Serotonin receptors expressed in Drosophila mushroom bodies differentially modulate larval locomotion. PLoS ONE. 2014;9:e89641 pubmed 出版商
Stuart S, Butler P, Munafò M, Nutt D, Robinson E. A translational rodent assay of affective biases in depression and antidepressant therapy. Neuropsychopharmacology. 2013;38:1625-35 pubmed 出版商
Kurita M, Holloway T, García Bea A, Kozlenkov A, Friedman A, Moreno J, et al. HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity. Nat Neurosci. 2012;15:1245-54 pubmed 出版商
Nozawa K, Kawabata Shoda E, Doihara H, Kojima R, Okada H, Mochizuki S, et al. TRPA1 regulates gastrointestinal motility through serotonin release from enterochromaffin cells. Proc Natl Acad Sci U S A. 2009;106:3408-13 pubmed 出版商
MacLean M, Deuchar G, Hicks M, Morecroft I, Shen S, Sheward J, et al. Overexpression of the 5-hydroxytryptamine transporter gene: effect on pulmonary hemodynamics and hypoxia-induced pulmonary hypertension. Circulation. 2004;109:2150-5 pubmed
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
0927
SKU号 :
0927/10
产品名称 :
盐酸氟西汀
描述 :
5-HT reuptake inhibitor
靶标 :
5-HT Transporter Inhibitors
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
99%
观察到的分子量 :
345.78
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor. Binds to the human 5-HT transporter with a Ki of 0.9 nmol/l and is between 150- and 900-fold selective over 5-HT1A, 5-HT2A, H1, 1, 2-adrenergic, and muscarinic receptors. Antidepressant. Induces differentiation of neuronal precursors, enhancing neuronal characteristics. Fluoxetine also inhibits assembly and activation of the NLRP3-ASC inflammasome and prevents degeneration of retinal pigmented epithelium (RPE) cells in an animal model of dry age-related macular degeneration (AMD).
extended description :
5-HT reuptake inhibitor
化学品名文本 :
N-Methyl-3-[(4-trifluoromethyl)phenoxy]-3-phenylpropylamine hydrochloride
配方 :
C 17 H 18 F 3 NO.氯化氢
配方文本 :
C17H18F3NO.氯化氢
cas num :
56296-78-7
美元 :
122美元
产品细节 :
5-HT reuptake inhibitor
储存 :
存放在RT
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国