产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
NS 398
目录 :
0942/10
规格 :
10 mg (also 50 mg)
价格 :
238美元
更多信息或购买 :
文章摘录数: 14
参考文献 |
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Messerschmidt L, Fischer S, Wiedemann P, Bringmann A, Hollborn M. Osmotic induction of cyclooxygenase-2 in RPE cells: Stimulation of inflammasome activation. Mol Vis. 2019;25:329-344 pubmed
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Sunters A, Armstrong V, Zaman G, Kypta R, Kawano Y, Lanyon L, et al. Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 r. J Biol Chem. 2010;285:8743-58 pubmed 出版商
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Ray N, Bisher M, Enquist L. Cyclooxygenase-1 and -2 are required for production of infectious pseudorabies virus. J Virol. 2004;78:12964-74 pubmed
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产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
0942
SKU号 :
0942/10
产品名称 :
NS 398
描述 :
Cyclooxygenase-2 (COX-2) inhibitor
靶标 :
环氧合酶抑制剂
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
99%
观察到的分子量 :
314.36
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
NS 398 is a selective cyclooxygenase-2 inhibitor (IC50 values are 3.8 and 100 u M for COX-2 and COX-1 respectively). Induces apoptosis in colorectal tumor cells and elevates COX-2 protein expression in vitro . Orally active and non-ulcerogenic analgesic and anti-inflammatory in vivo .
extended description :
Cyclooxygenase-2 (COX-2) inhibitor
化学品名文本 :
N-[2-Cyclohexyloxy-4-nitrophenyl]methanesulfonamide
配方 :
C 13 H 18 N 2 O 5秒
配方文本 :
C13H18N2O5S
cas num :
123653-11-2
美元 :
238美元
产品细节 :
Cyclooxygenase-2 (COX-2) inhibitor
储存 :
存放在RT
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
公司总部: 英国