产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
放线菌酮
目录 :
0970/100
规格 :
100毫克
价格 :
103美元
更多信息或购买 :
Tocris Bioscience 产品网页
文章摘录数: 18
参考文献
Paige C, Mejia G, Dussor G, PRICE T. AMPK activation regulates P-body dynamics in mouse sensory neurons in vitro and in vivo. Neurobiol Pain. 2019;5: pubmed 出版商
Zhang X, Zhao Y, Wang C, Ju H, Liu W, Zhang X, et al. Rhomboid domain-containing protein 1 promotes breast cancer progression by regulating the p-Akt and CDK2 levels. Cell Commun Signal. 2018;16:65 pubmed 出版商
Paul S, Dansithong W, Figueroa K, Scoles D, Pulst S. Staufen1 links RNA stress granules and autophagy in a model of neurodegeneration. Nat Commun. 2018;9:3648 pubmed 出版商
Wu N, Tasker J. Nongenomic Glucocorticoid Suppression of a Postsynaptic Potassium Current via Emergent Autocrine Endocannabinoid Signaling in Hypothalamic Neuroendocrine Cells following Chronic Dehydration. Eneuro. 2017;4: pubmed 出版商
Di S, Itoga C, Fisher M, Solomonow J, Roltsch E, Gilpin N, et al. Acute Stress Suppresses Synaptic Inhibition and Increases Anxiety via Endocannabinoid Release in the Basolateral Amygdala. J Neurosci. 2016;36:8461-70 pubmed 出版商
Wiedermann G, Bone R, Silva J, Björklund M, Murray P, Dale J. A balance of positive and negative regulators determines the pace of the segmentation clock. elife. 2015;4:e05842 pubmed 出版商
Briz V, Zhu G, Wang Y, Liu Y, Avetisyan M, Bi X, et al. Activity-dependent rapid local RhoA synthesis is required for hippocampal synaptic plasticity. J Neurosci. 2015;35:2269-82 pubmed 出版商
Bhatnagar S, Soni M, Wrighton L, Hebert A, Zhou A, Paul P, et al. Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion. J Biol Chem. 2014;289:25276-86 pubmed 出版商
Gupta A, Gomes I, Wardman J, Devi L. Opioid receptor function is regulated by post-endocytic peptide processing. J Biol Chem. 2014;289:19613-26 pubmed 出版商
Wang Y, Zhu G, Briz V, Hsu Y, Bi X, Baudry M. A molecular brake controls the magnitude of long-term potentiation. Nat Commun. 2014;5:3051 pubmed 出版商
Ramiro Cortés Y, Israely I. Long lasting protein synthesis- and activity-dependent spine shrinkage and elimination after synaptic depression. PLoS ONE. 2013;8:e71155 pubmed 出版商
Bernard P, Castano A, O Leary H, Simpson K, Browning M, Benke T. Phosphorylation of FMRP and alterations of FMRP complex underlie enhanced mLTD in adult rats triggered by early life seizures. Neurobiol Dis. 2013;59:1-17 pubmed 出版商
Pont J, McArdle C, Lopez Bernal A. Oxytocin-stimulated NFAT transcriptional activation in human myometrial cells. Mol Endocrinol. 2012;26:1743-56 pubmed
Zhao W, Chuang S, Bianchi R, Wong R. Dual regulation of fragile X mental retardation protein by group I metabotropic glutamate receptors controls translation-dependent epileptogenesis in the hippocampus. J Neurosci. 2011;31:725-34 pubmed 出版商
Huang Y, Yang C, Huang C, Tai M, Hsu K. Pharmacological and genetic accumulation of hypoxia-inducible factor-1alpha enhances excitatory synaptic transmission in hippocampal neurons through the production of vascular endothelial growth factor. J Neurosci. 2010;30:6080-93 pubmed 出版商
Argadine H, Hellyer N, Mantilla C, Zhan W, Sieck G. The effect of denervation on protein synthesis and degradation in adult rat diaphragm muscle. J Appl Physiol (1985). 2009;107:438-44 pubmed 出版商
Wong S, Leung F, Lau C, Au C, Yung L, Yao X, et al. Cyclooxygenase-2-derived prostaglandin F2alpha mediates endothelium-dependent contractions in the aortae of hamsters with increased impact during aging. Circ Res. 2009;104:228-35 pubmed 出版商
Chan J, Cheng H, Chou J, Li F, Dai K, Chan S, et al. Heat shock protein 60 or 70 activates nitric-oxide synthase (NOS) I- and inhibits NOS II-associated signaling and depresses the mitochondrial apoptotic cascade during brain stem death. J Biol Chem. 2007;282:4585-600 pubmed
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
0970
SKU号 :
0970/100
产品名称 :
放线菌酮
描述 :
Inhibitor of protein synthesis
靶标 :
脱氧核糖核酸, 核糖核酸和蛋白质合成酶抑制剂
类别 :
Small Molecules
单位尺寸 :
100毫克
纯度 :
97%
观察到的分子量 :
281.35
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
Cycloheximide is a selective inhibitor of eukaryotic (over prokaryotic) protein synthesis, blocking tRNA binding and release from ribosomes. Induces apoptosis in a variety of transformed and normal cell lines, including T cells. Competitively inhibits the PPIase hFKBP12 (Ki = 3.4 M). Also inhibits ferroptosis. Antifungal antibiotic. Exhibits anti-MERS-CoV activity in Vero cells in vitro (IC50 = 0.16 M).
extended description :
Inhibitor of protein synthesis
化学品名文本 :
4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione
配方 :
C 15 H 23 NO 4
配方文本 :
C15H23NO4
cas num :
66-81-9
美元 :
103美元
产品细节 :
Inhibitor of protein synthesis
储存 :
Desiccate at RT
更多信息或购买 :
Tocris Bioscience 产品网页
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国