产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
CP 93129 dihydrochloride
目录 :
1032/10
规格 :
10 mg (also 50 mg)
价格 :
227美元
更多信息或购买 :
文章摘录数: 9
参考文献
Zhou M, Sun F, Xu C, Chen H, Qiao H, Cai X, et al. Modulation of Kalirin-7 expression by hippocampal CA1 5-HT1B receptors in spatial memory consolidation. Behav Brain Res. 2019;356:148-155 pubmed 出版商
Medrihan L, Sagi Y, Inde Z, Krupa O, Daniels C, Peyrache A, et al. Initiation of Behavioral Response to Antidepressants by Cholecystokinin Neurons of the Dentate Gyrus. Neuron. 2017;95:564-576.e4 pubmed 出版商
Hirono M, Nagao S, Yanagawa Y, Konishi S. Monoaminergic modulation of GABAergic transmission onto cerebellar globular cells. Neuropharmacology. 2017;118:79-89 pubmed 出版商
Majeed Z, Abdeljaber E, Soveland R, Cornwell K, Bankemper A, Koch F, et al. Modulatory Action by the Serotonergic System: Behavior and Neurophysiology in Drosophila melanogaster. Neural Plast. 2016;2016:7291438 pubmed 出版商
Watts S, Darios E, Seitz B, Thompson J. 5-HT is a potent relaxant in rat superior mesenteric veins. Pharmacol Res Perspect. 2015;3:e00103 pubmed 出版商
Guo J, Rainnie D. Presynaptic 5-HT(1B) receptor-mediated serotonergic inhibition of glutamate transmission in the bed nucleus of the stria terminalis. Neuroscience. 2010;165:1390-401 pubmed 出版商
Watakabe A, Komatsu Y, Sadakane O, Shimegi S, Takahata T, Higo N, et al. Enriched expression of serotonin 1B and 2A receptor genes in macaque visual cortex and their bidirectional modulatory effects on neuronal responses. Cereb Cortex. 2009;19:1915-28 pubmed 出版商
Heisler L, Jobst E, Sutton G, Zhou L, Borok E, Thornton Jones Z, et al. Serotonin reciprocally regulates melanocortin neurons to modulate food intake. Neuron. 2006;51:239-49 pubmed
Rau K, Birdsall E, Volz T, Riordan J, Baucum A, Adair B, et al. Methamphetamine administration reduces hippocampal vesicular monoamine transporter-2 uptake. J Pharmacol Exp Ther. 2006;318:676-82 pubmed
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
1032
SKU号 :
1032/10
产品名称 :
CP 93129 dihydrochloride
描述 :
5-HT1B agonist
靶标 :
5-HT1B Receptor Agonists
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
观察到的分子量 :
288.18
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
CP 93129 dihydrochloride is a potent and highly selective 5-HT1B agonist (Ki values are 8.1, 1100, 1500, 2900 and 7200 nM for 5-HT1B, 5-HT1D, 5-HT1A, 5-HT1c and 5-HT2, respectively). Reduces food intake and decreases body weight in rats.
extended description :
5-HT1B agonist
化学品名文本 :
1,4-Dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one dihydrochloride
配方 :
C 12 H 13 N 3 O.2HCl
配方文本 :
C12H13N3O.2HCl
cas num :
879089-64-2
美元 :
227美元
产品细节 :
5-HT1B agonist
储存 :
Desiccate at RT
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国