产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
染料木素
目录 :
1110/10
规格 :
10 mg (also 50 mg)
价格 :
80美元
更多信息或购买 :
Tocris Bioscience 产品网页
文章摘录数: 10
参考文献
Kim J, Leem Y, Kwon I, Kang J, Bae Y, Cho H. Estrogen modulates serotonin effects on vasoconstriction through Src inhibition. Exp Mol Med. 2018;50:167 pubmed 出版商
Olianas M, Dedoni S, Onali P. The GABAB positive allosteric modulators CGP7930 and GS39783 stimulate ERK1/2 signalling in cells lacking functional GABAB receptors. Eur J Pharmacol. 2017;794:135-146 pubmed 出版商
Liu Z, Chen J, Mirando A, Wang C, Zuscik M, O Keefe R, et al. A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritis. Sci Signal. 2015;8:ra71 pubmed 出版商
Accardi M, Brown P, Miraucourt L, Orser B, Bowie D. α6-Containing GABAA Receptors Are the Principal Mediators of Inhibitory Synapse Strengthening by Insulin in Cerebellar Granule Cells. J Neurosci. 2015;35:9676-88 pubmed 出版商
Mansouri Attia N, James R, Ligon A, Li X, Pangas S. Soy promotes juvenile granulosa cell tumor development in mice and in the human granulosa cell tumor-derived COV434 cell line. Biol Reprod. 2014;91:100 pubmed 出版商
Bigford G, Chaudhry N, Keane R, Holohean A. 5-Hydroxytryptamine 5HT2C receptors form a protein complex with N-methyl-D-aspartate GluN2A subunits and activate phosphorylation of Src protein to modulate motoneuronal depolarization. J Biol Chem. 2012;287:11049-59 pubmed 出版商
Li C, Dabrowska J, Hazra R, Rainnie D. Synergistic activation of dopamine D1 and TrkB receptors mediate gain control of synaptic plasticity in the basolateral amygdala. PLoS ONE. 2011;6:e26065 pubmed 出版商
Melis M, Pillolla G, Luchicchi A, Muntoni A, Yasar S, Goldberg S, et al. Endogenous fatty acid ethanolamides suppress nicotine-induced activation of mesolimbic dopamine neurons through nuclear receptors. J Neurosci. 2008;28:13985-94 pubmed 出版商
Rojas A, Cui N, Su J, Yang L, Muhumuza J, Jiang C. Protein kinase C dependent inhibition of the heteromeric Kir4.1-Kir5.1 channel. Biochim Biophys Acta. 2007;1768:2030-42 pubmed
Alao J, Stavropoulou A, Lam E, Coombes R. Role of glycogen synthase kinase 3 beta (GSK3beta) in mediating the cytotoxic effects of the histone deacetylase inhibitor trichostatin A (TSA) in MCF-7 breast cancer cells. Mol Cancer. 2006;5:40 pubmed
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
1110
SKU号 :
1110/10
产品名称 :
染料木素
描述 :
EGFR kinase inhibitor. Also estrogen and PPAR ligand
靶标 :
EGF Receptor Inhibitors
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
98%
观察到的分子量 :
270.24
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
Genistein is a phytoestrogen with a wide range of biological actions. Genistein inhibits protein tyrosine kinases including epidermal growth factor receptor kinase, binds to PPAR and estrogen receptors and acts as an agonist at GPER. Genistein inhibits aggregation and fibrilization of A 42 and amylin37 (hiAPP). In Huntington s disease fibroblast cells, Genistein reduces intracellular mutant huntingtin (mHTT) aggregates and induces degradation of mHTT; in a cellular model of Huntington s disease, Genistein corrects the mutant phenotype through stimulation of autophagy.
extended description :
EGFR kinase inhibitor. Also estrogen and PPAR ligand
化学品名文本 :
5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
配方 :
C 15 H 10 O 5
配方文本 :
C15H10O5
cas num :
446-72-0
美元 :
80美元
产品细节 :
EGFR kinase inhibitor. Also estrogen and PPAR ligand
储存 :
Desiccate at -20°C
更多信息或购买 :
Tocris Bioscience 产品网页
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国