产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
A23187, free acid
目录 :
1234/10
规格 :
10毫克
价格 :
202美元
更多信息或购买 :
Tocris Bioscience 产品网页
文章摘录数: 11
参考文献
Megia Fernandez A, Mills B, Michels C, Chankeshwara S, Krstajic N, Haslett C, et al. Bimodal fluorogenic sensing of matrix proteolytic signatures in lung cancer. Org Biomol Chem. 2018;16:8056-8063 pubmed 出版商
Goldberg J, Currais A, Prior M, Fischer W, Chiruta C, RATLIFF E, et al. The mitochondrial ATP synthase is a shared drug target for aging and dementia. Aging Cell. 2018;17: pubmed 出版商
Wajih N, Basu S, Jailwala A, Kim H, Ostrowski D, Perlegas A, et al. Potential therapeutic action of nitrite in sickle cell disease. Redox Biol. 2017;12:1026-1039 pubmed 出版商
Hou L, Liu K, Li Y, Ma S, Ji X, Liu L. Necrotic pyknosis is a morphologically and biochemically distinct event from apoptotic pyknosis. J Cell Sci. 2016;129:3084-90 pubmed 出版商
Cahalan S, Lukacs V, Ranade S, Chien S, Bandell M, Patapoutian A. Piezo1 links mechanical forces to red blood cell volume. elife. 2015;4: pubmed 出版商
Diaz M, Li N, Lee H, Adamo L, Evans S, Willey H, et al. Biomechanical forces promote blood development through prostaglandin E2 and the cAMP-PKA signaling axis. J Exp Med. 2015;212:665-80 pubmed 出版商
Schöndorf D, Aureli M, McAllister F, Hindley C, Mayer F, Schmid B, et al. iPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis. Nat Commun. 2014;5:4028 pubmed 出版商
Harper M, Poole A. Chloride channels are necessary for full platelet phosphatidylserine exposure and procoagulant activity. Cell Death Dis. 2013;4:e969 pubmed 出版商
Yung M, Chan D, Liu V, Yao K, Ngan H. Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade. BMC Cancer. 2013;13:327 pubmed 出版商
Cheang W, Wong W, Tian X, Yang Q, Lee H, He G, et al. Endothelial nitric oxide synthase enhancer reduces oxidative stress and restores endothelial function in db/db mice. Cardiovasc Res. 2011;92:267-75 pubmed 出版商
Arozarena I, Sanchez Laorden B, Packer L, Hidalgo Carcedo C, Hayward R, Viros A, et al. Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A. Cancer Cell. 2011;19:45-57 pubmed 出版商
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
1234
SKU号 :
1234/10
产品名称 :
A23187, free acid
描述 :
钙离子载体
靶标 :
Calcium Signaling Agents
类别 :
Small Molecules
单位尺寸 :
10毫克
纯度 :
98%
观察到的分子量 :
523.63
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
A23187, free acid is a calcium ionophore that induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Promotes intracelllular ROS generation and platelet particle formation (fragmentation) in vitro and in vivo . Can be used to induce autophagy in mammalian cells.
extended description :
钙离子载体
化学品名文本 :
5-(Methylamino)-2-[[2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)-ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid
配方 :
C 29 H 37 N 3 O 6
配方文本 :
C29H37N3O6
cas num :
52665-69-7
美元 :
202美元
产品细节 :
钙离子载体
别名 :
卡西霉素
储存 :
存放在+4°C
更多信息或购买 :
Tocris Bioscience 产品网页
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国