产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
LY 367385
目录 :
1237/10
规格 :
10 mg (also 50 mg)
价格 :
222美元
更多信息或购买 :
文章摘录数: 47
参考文献
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Tang A, Alger B. Homer protein-metabotropic glutamate receptor binding regulates endocannabinoid signaling and affects hyperexcitability in a mouse model of fragile X syndrome. J Neurosci. 2015;35:3938-45 pubmed 出版商
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Boulware M, Heisler J, Frick K. The memory-enhancing effects of hippocampal estrogen receptor activation involve metabotropic glutamate receptor signaling. J Neurosci. 2013;33:15184-94 pubmed 出版商
Ramiro Cortés Y, Israely I. Long lasting protein synthesis- and activity-dependent spine shrinkage and elimination after synaptic depression. PLoS ONE. 2013;8:e71155 pubmed 出版商
Clem R, Huganir R. Norepinephrine enhances a discrete form of long-term depression during fear memory storage. J Neurosci. 2013;33:11825-32 pubmed 出版商
Dominguez R, Dewing P, Kuo J, Micevych P. Membrane-initiated estradiol signaling in immortalized hypothalamic N-38 neurons. Steroids. 2013;78:607-13 pubmed 出版商
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Jurgens C, Bell K, McQuiston A, Guido W. Optogenetic stimulation of the corticothalamic pathway affects relay cells and GABAergic neurons differently in the mouse visual thalamus. PLoS ONE. 2012;7:e45717 pubmed 出版商
Bozdagi O, Sakurai T, Dorr N, Pilorge M, Takahashi N, Buxbaum J. Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice. PLoS ONE. 2012;7:e42422 pubmed 出版商
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Zhang P, Lisman J. Activity-dependent regulation of synaptic strength by PSD-95 in CA1 neurons. J Neurophysiol. 2012;107:1058-66 pubmed 出版商
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产品信息
品牌 :
Tocris
master code :
1237
SKU号 :
1237/10
产品名称 :
LY 367385
描述 :
Selective mGlu1a antagonist
靶标 :
Group I mGluR Antagonists
类别 :
Small Molecules
sizes available :
10 mg (also 50 mg)
纯度 :
99%
观察到的分子量 :
209.2
网址印刷 :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
LY 367385 is a selective mGlu1a receptor antagonist, with an IC50 value of 8.8 u M for blockade of quisqualate-induced phosphoinositide hydrolysis vs. 100 u M for mGlu5a, and negligible action on group II and III receptors.
extended description :
Selective mGlu1a antagonist
化学品名文本 :
(S)-(+)- -Amino-4-carboxy-2-methylbenzeneacetic acid
配方 :
C 10 H 11 NO 4
配方文本 :
C10H11NO4
cas num :
198419-91-9
美元 :
211
美元2023 :
222美元
产品细节 :
Selective mGlu1a antagonist
储存 :
Desiccate at RT
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国