产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
(+)-PD 128907 hydrochloride
目录 :
1243/10
规格 :
10 mg (also 50 mg)
价格 :
368美元
更多信息或购买 :
文章摘录数: 9
参考文献
Shin S, Pribiag H, Lilascharoen V, Knowland D, Wang X, Lim B. Drd3 Signaling in the Lateral Septum Mediates Early Life Stress-Induced Social Dysfunction. Neuron. 2018;97:195-208.e6 pubmed 出版商
Chai H, Diaz Castro B, Shigetomi E, Monte E, Octeau J, Yu X, et al. Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence. Neuron. 2017;95:531-549.e9 pubmed 出版商
Cote S, Kuzhikandathil E. Chronic levodopa treatment alters expression and function of dopamine D3 receptor in the MPTP/p mouse model of Parkinson's disease. Neurosci Lett. 2015;585:33-7 pubmed 出版商
Schulz S, Heidmann K, Mike A, Klaft Z, Heinemann U, Gerevich Z. First and second generation antipsychotics influence hippocampal gamma oscillations by interactions with 5-HT3 and D3 receptors. Br J Pharmacol. 2012;167:1480-91 pubmed 出版商
Marcellino D, Ferre S, Casado V, Cortes A, Le Foll B, Mazzola C, et al. Identification of dopamine D1-D3 receptor heteromers. Indications for a role of synergistic D1-D3 receptor interactions in the striatum. J Biol Chem. 2008;283:26016-25 pubmed 出版商
Zapata A, Kivell B, Han Y, Javitch J, Bolan E, Kuraguntla D, et al. Regulation of dopamine transporter function and cell surface expression by D3 dopamine receptors. J Biol Chem. 2007;282:35842-54 pubmed
Basso A, Gallagher K, Bratcher N, Brioni J, Moreland R, Hsieh G, et al. Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test. Neuropsychopharmacology. 2005;30:1257-68 pubmed
Clemens S, Hochman S. Conversion of the modulatory actions of dopamine on spinal reflexes from depression to facilitation in D3 receptor knock-out mice. J Neurosci. 2004;24:11337-45 pubmed
Zhang L, Lou D, Jiao H, Zhang D, Wang X, Xia Y, et al. Cocaine-induced intracellular signaling and gene expression are oppositely regulated by the dopamine D1 and D3 receptors. J Neurosci. 2004;24:3344-54 pubmed
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
1243
SKU号 :
1243/10
产品名称 :
(+)-PD 128907 hydrochloride
描述 :
High affinity D3 agonist (D3 D2 D4)
靶标 :
Dopamine D3 Receptor Agonists
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
98%
观察到的分子量 :
285.77
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
(+)-PD 128907 hydrochloride is a high affinity D3 dopamine receptor agonist (Ki = 2.3 nM). Displays 18 - 200-fold selectivity over other dopamine receptor subtypes.
extended description :
High affinity D3 agonist (D3 D2 D4)
化学品名文本 :
(4aR,10bR)-3,4a,4,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano-[4,3-b]-1,4-oxazin-9-ol hydrochloride
配方 :
C 14 H 19 NO 3。 氯化氢
配方文本 :
C14H19NO3.氯化氢
cas num :
300576-59-4
美元 :
368美元
产品细节 :
High affinity D3 agonist (D3 D2 D4)
储存 :
存放在+4°C
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国