产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
CGP 35348
目录 :
1245/10
规格 :
10 mg (also 50 mg)
价格 :
253美元
更多信息或购买 :
文章摘录数: 11
参考文献
Zhao J, Li A, Rajsombath M, Dang Y, Selkoe D, Li S. Soluble A? Oligomers Impair Dipolar Heterodendritic Plasticity by Activation of mGluR in the Hippocampal CA1 Region. iScience. 2018;6:138-150 pubmed 出版商
Huang S, Green M, de Carvalho A, Mumau M, Chen Y, D Souza S, et al. The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells. Nat Protoc. 2015;10:413-25 pubmed 出版商
Aubdool A, Graepel R, Kodji X, Alawi K, Bodkin J, Srivastava S, et al. TRPA1 is essential for the vascular response to environmental cold exposure. Nat Commun. 2014;5:5732 pubmed 出版商
Xia Y, Zhao Y, Yang M, Zeng S, Shu Y. Regulation of action potential waveforms by axonal GABAA receptors in cortical pyramidal neurons. PLoS ONE. 2014;9:e100968 pubmed 出版商
Vashchinkina E, Manner A, Vekovischeva O, den Hollander B, Uusi Oukari M, Aitta Aho T, et al. Neurosteroid Agonist at GABAA receptor induces persistent neuroplasticity in VTA dopamine neurons. Neuropsychopharmacology. 2014;39:727-37 pubmed 出版商
Gantz S, Bunzow J, Williams J. Spontaneous inhibitory synaptic currents mediated by a G protein-coupled receptor. Neuron. 2013;78:807-12 pubmed 出版商
Gantz S, Ford C, Neve K, Williams J. Loss of Mecp2 in substantia nigra dopamine neurons compromises the nigrostriatal pathway. J Neurosci. 2011;31:12629-37 pubmed 出版商
Lecrux C, Toussay X, Kocharyan A, Fernandes P, Neupane S, Levesque M, et al. Pyramidal neurons are "neurogenic hubs" in the neurovascular coupling response to whisker stimulation. J Neurosci. 2011;31:9836-47 pubmed 出版商
Gaier E, Rodriguiz R, Ma X, Sivaramakrishnan S, Bousquet Moore D, Wetsel W, et al. Haploinsufficiency in peptidylglycine alpha-amidating monooxygenase leads to altered synaptic transmission in the amygdala and impaired emotional responses. J Neurosci. 2010;30:13656-69 pubmed 出版商
Milenkovic I, Witte M, Turecek R, Heinrich M, Reinert T, Rubsamen R. Development of chloride-mediated inhibition in neurons of the anteroventral cochlear nucleus of gerbil (Meriones unguiculatus). J Neurophysiol. 2007;98:1634-44 pubmed
Wood M, Murkitt K, Rice S, Testa T, Punia P, Stammers M, et al. The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen. Br J Pharmacol. 2000;131:1050-4 pubmed
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
1245
SKU号 :
1245/10
产品名称 :
CGP 35348
描述 :
Selective GABAB antagonist; brain penetrant
靶标 :
GABA-B Receptor Antagonists
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
观察到的分子量 :
225.22
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
CGP 35348 is a selective, brain penetrant GABAB receptor antagonist (IC50 = 34 u M as measured in rat cortical membranes). Has higher affinity for postsynaptic versus presynaptic receptors.
extended description :
Selective GABAB antagonist; brain penetrant
化学品名文本 :
(3-Aminopropyl)(diethoxymethyl)phosphinic acid
配方 :
C 8 H 20 NO 4 P
配方文本 :
C8H20NO4P
cas num :
123690-79-9
美元 :
253美元
产品细节 :
Selective GABAB antagonist; brain penetrant
储存 :
存放在RT
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国