产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
CGP 52432
目录 :
1246/10
规格 :
10 mg (also 50 mg)
价格 :
284美元
更多信息或购买 :
文章摘录数: 22
参考文献
Vergassola M, Olivero G, Cisani F, Usai C, Bossi S, Puliti A, et al. Presynaptic mGlu1 Receptors Control GABAB Receptors in an Antagonist-Like Manner in Mouse Cortical GABAergic and Glutamatergic Nerve Endings. Front Mol Neurosci. 2018;11:324 pubmed 出版商
Sargin D, Oliver D, Lambe E. Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels. elife. 2016;5: pubmed 出版商
Kim K, Ramiro Diaz J, Iddings J, Filosa J. Vasculo-Neuronal Coupling: Retrograde Vascular Communication to Brain Neurons. J Neurosci. 2016;36:12624-12639 pubmed
Lee M, Nam T, Jung S, Gwak Y, Leem J. Modulation of Spinal GABAergic Inhibition and Mechanical Hypersensitivity following Chronic Compression of Dorsal Root Ganglion in the Rat. Neural Plast. 2015;2015:924728 pubmed 出版商
Bragina L, Bonifacino T, Bassi S, Milanese M, Bonanno G, Conti F. Differential expression of metabotropic glutamate and GABA receptors at neocortical glutamatergic and GABAergic axon terminals. Front Cell Neurosci. 2015;9:345 pubmed 出版商
Dobson K, Jackson C, Balakrishnan S, Bellamy T. Caffeine Modulates Vesicle Release and Recovery at Cerebellar Parallel Fibre Terminals, Independently of Calcium and Cyclic AMP Signalling. PLoS ONE. 2015;10:e0125974 pubmed 出版商
Mans R, Warmus B, Smith C, McMahon L. An acetylcholinesterase inhibitor, eserine, induces long-term depression at CA3-CA1 synapses in the hippocampus of adult rats. J Neurophysiol. 2014;112:2388-97 pubmed 出版商
Yang S, Chung P, Ho C, Kuo C, Hung M, Huang Y, et al. Propofol inhibits superoxide production, elastase release, and chemotaxis in formyl peptide-activated human neutrophils by blocking formyl peptide receptor 1. J Immunol. 2013;190:6511-9 pubmed 出版商
Venkataraman Y, Bartlett E. Postnatal development of synaptic properties of the GABAergic projection from the inferior colliculus to the auditory thalamus. J Neurophysiol. 2013;109:2866-82 pubmed 出版商
Song I, Volynski K, Brenner T, Ushkaryov Y, Walker M, Semyanov A. Different transporter systems regulate extracellular GABA from vesicular and non-vesicular sources. Front Cell Neurosci. 2013;7:23 pubmed 出版商
Marrocco J, Mairesse J, Ngomba R, Silletti V, Van Camp G, Bouwalerh H, et al. Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus. J Neurosci. 2012;32:17143-54 pubmed 出版商
Chacón M, Navarro A, Cuesto G, del Pino I, Scott R, Morales M, et al. Focal adhesion kinase regulates actin nucleation and neuronal filopodia formation during axonal growth. Development. 2012;139:3200-10 pubmed 出版商
Xiao Y, Huang X, Van Wert S, Barreto E, Wu J, Gluckman B, et al. The role of inhibition in oscillatory wave dynamics in the cortex. Eur J Neurosci. 2012;36:2201-12 pubmed 出版商
Caiati M, Sivakumaran S, Lanore F, Mulle C, Richard E, Verrier D, et al. Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses. Sci Rep. 2012;2:285 pubmed 出版商
Parker J, WANAT M, Soden M, Ahmad K, Zweifel L, Bamford N, et al. Attenuating GABA(A) receptor signaling in dopamine neurons selectively enhances reward learning and alters risk preference in mice. J Neurosci. 2011;31:17103-12 pubmed 出版商
Li C, Dabrowska J, Hazra R, Rainnie D. Synergistic activation of dopamine D1 and TrkB receptors mediate gain control of synaptic plasticity in the basolateral amygdala. PLoS ONE. 2011;6:e26065 pubmed 出版商
Lam D, Leinninger G, Louis G, Garfield A, Marston O, Leshan R, et al. Leptin does not directly affect CNS serotonin neurons to influence appetite. Cell Metab. 2011;13:584-91 pubmed 出版商
Adedoyin M, Vicini S, Neale J. Endogenous N-acetylaspartylglutamate (NAAG) inhibits synaptic plasticity/transmission in the amygdala in a mouse inflammatory pain model. Mol Pain. 2010;6:60 pubmed 出版商
Wu P, Coultrap S, Browning M, Proctor W. Correlated changes in NMDA receptor phosphorylation, functional activity, and sedation by chronic ethanol consumption. J Neurochem. 2010;115:1112-22 pubmed 出版商
Moore S, Cooper D, Spruston N. Plasticity of burst firing induced by synergistic activation of metabotropic glutamate and acetylcholine receptors. Neuron. 2009;61:287-300 pubmed 出版商
Kelm M, Criswell H, Breese G. The role of protein kinase A in the ethanol-induced increase in spontaneous GABA release onto cerebellar Purkinje neurons. J Neurophysiol. 2008;100:3417-28 pubmed 出版商
Jensen T, Filoteo A, Knopfel T, Empson R. Presynaptic plasma membrane Ca2+ ATPase isoform 2a regulates excitatory synaptic transmission in rat hippocampal CA3. J Physiol. 2007;579:85-99 pubmed
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
1246
SKU号 :
1246/10
产品名称 :
CGP 52432
描述 :
Potent and selective GABAB antagonist
靶标 :
GABA-B Receptor Antagonists
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
98%
观察到的分子量 :
384.24
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
CGP 52432 is a potent, selective GABAB receptor antagonist (IC50 = 85 nM).
extended description :
Potent and selective GABAB antagonist
化学品名文本 :
3-[[(3,4-Dichlorophenyl)methyl]amino]propyl] diethoxymethyl)phosphinic acid
配方 :
C 15 H 24 Cl 2 NO 4 P
配方文本 :
C15H24Cl2NO4P
cas num :
139667-74-6
美元 :
284美元
产品细节 :
Potent and selective GABAB antagonist
储存 :
存放在+4°C
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国