产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
(S)-WAY 100135 dihydrochloride
目录 :
1253/10
规格 :
10 mg (also 50 mg)
价格 :
210美元
更多信息或购买 :
文章摘录数: 6
参考文献
Saxena S, Roselli F, Singh K, Leptien K, Julien J, Gros Louis F, et al. Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival. Neuron. 2013;80:80-96 pubmed 出版商
Pandya A, Yakel J. Activation of the α7 nicotinic ACh receptor induces anxiogenic effects in rats which is blocked by a 5-HT₁a receptor antagonist. Neuropharmacology. 2013;70:35-42 pubmed 出版商
Grace K, Liu H, Horner R. 5-HT1A receptor-responsive pedunculopontine tegmental neurons suppress REM sleep and respiratory motor activity. J Neurosci. 2012;32:1622-33 pubmed 出版商
Chambers J, Bornstein J, Thomas E. Multiple neural oscillators and muscle feedback are required for the intestinal fed state motor program. PLoS ONE. 2011;6:e19597 pubmed 出版商
Foong J, Parry L, Gwynne R, Bornstein J. 5-HT(1A), SST(1), and SST(2) receptors mediate inhibitory postsynaptic potentials in the submucous plexus of the guinea pig ileum. Am J Physiol Gastrointest Liver Physiol. 2010;298:G384-94 pubmed 出版商
Hampson L, Mackin P, Agius L. Stimulation of glycogen synthesis and inactivation of phosphorylase in hepatocytes by serotonergic mechanisms, and counter-regulation by atypical antipsychotic drugs. Diabetologia. 2007;50:1743-51 pubmed
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
1253
SKU号 :
1253/10
产品名称 :
(S)-WAY 100135 dihydrochloride
描述 :
Potent and selective 5-HT1A antagonist
靶标 :
5-HT1A Receptor Antagonists
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
99%
观察到的分子量 :
468.47
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
( S )-WAY 100135 dihydrochloride is a potent, selective 5-HT1A receptor antagonist (IC50 = 15 nM). Selective over 5-HT1B, 1C, 2, 1, 2 and D2 receptors (IC50 1000 nM). Centrally active on systemic administration.
extended description :
Potent and selective 5-HT1A antagonist
化学品名文本 :
(S)-N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide dihydrochloride
配方 :
C 24 H 33 N 3 O 2。 2HCl
配方文本 :
C24H33N3O2.2HCl
cas num :
149007-54-5
美元 :
210美元
产品细节 :
Potent and selective 5-HT1A antagonist
储存 :
Desiccate at +4°C
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国