参考文献 |
---|
Chen Y, Tristan C, Chen L, Jovanovic V, Malley C, Chu P, et al. A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells. Nat Methods. 2021;18:528-541 pubmed 出版商
|
Kim T, Piao J, Koo S, Kriks S, Chung S, Betel D, et al. Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use. Cell Stem Cell. 2021;28:343-355.e5 pubmed 出版商
|
Piao J, Zabierowski S, Dubose B, Hill E, Navare M, Claros N, et al. Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01. Cell Stem Cell. 2021;28:217-229.e7 pubmed 出版商
|
Leibel S, McVicar R, Winquist A, Niles W, Snyder E. Generation of Complete Multi-Cell Type Lung Organoids From Human Embryonic and Patient-Specific Induced Pluripotent Stem Cells for Infectious Disease Modeling and Therapeutics Validation. Curr Protoc Stem Cell Biol. 2020;54:e118 pubmed 出版商
|
Panciera T, Citron A, Di Biagio D, Battilana G, Gandin A, Giulitti S, et al. Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties. Nat Mater. 2020;19:797-806 pubmed 出版商
|
Bryant J, Batis N, Franke A, Clancey G, Hartley M, Ryan G, et al. Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma. Oncotarget. 2019;10:5229-5244 pubmed 出版商
|
Duman J, Mulherkar S, Tu Y, Erikson K, Tzeng C, Mavratsas V, et al. The adhesion-GPCR BAI1 shapes dendritic arbors via Bcr-mediated RhoA activation causing late growth arrest. elife. 2019;8: pubmed 出版商
|
Schwedhelm I, Zdzieblo D, Appelt Menzel A, Berger C, Schmitz T, Schuldt B, et al. Automated real-time monitoring of human pluripotent stem cell aggregation in stirred tank reactors. Sci Rep. 2019;9:12297 pubmed 出版商
|
Crowell P, Fox J, Hashimoto T, Diaz J, Navarro H, Henry G, et al. Expansion of Luminal Progenitor Cells in the Aging Mouse and Human Prostate. Cell Rep. 2019;28:1499-1510.e6 pubmed 出版商
|
Vattulainen M, Ilmarinen T, Koivusalo L, Viiri K, Hongisto H, Skottman H. Modulation of Wnt/BMP pathways during corneal differentiation of hPSC maintains ABCG2-positive LSC population that demonstrates increased regenerative potential. Stem Cell Res Ther. 2019;10:236 pubmed 出版商
|
Aureille J, Buffière Ribot V, Harvey B, Boyault C, Pernet L, Andersen T, et al. Nuclear envelope deformation controls cell cycle progression in response to mechanical force. EMBO Rep. 2019;20:e48084 pubmed 出版商
|
Hladik D, Höfig I, Oestreicher U, Beckers J, Matjanovski M, Bao X, et al. Long-term culture of mesenchymal stem cells impairs ATM-dependent recognition of DNA breaks and increases genetic instability. Stem Cell Res Ther. 2019;10:218 pubmed 出版商
|
Sharma P, Mesci P, Carromeu C, McClatchy D, Schiapparelli L, Yates J, et al. Exosomes regulate neurogenesis and circuit assembly. Proc Natl Acad Sci U S A. 2019;116:16086-16094 pubmed 出版商
|
Park S, Kim R, Park B, Lee S, Choi S, Park J, et al. Dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction. Nat Commun. 2019;10:3123 pubmed 出版商
|
Rehbach K, Kesavan J, Hauser S, Ritzenhofen S, Jungverdorben J, Schule R, et al. Multiparametric rapid screening of neuronal process pathology for drug target identification in HSP patient-specific neurons. Sci Rep. 2019;9:9615 pubmed 出版商
|
Wang Y, Shou Z, Fan H, Xu M, Chen Q, Tang Q, et al. Protective effects of oxymatrine against DSS-induced acute intestinal inflammation in mice via blocking the RhoA/ROCK signaling pathway. Biosci Rep. 2019;39: pubmed 出版商
|
Wilke G, Funkhouser Jones L, Wang Y, Ravindran S, Wang Q, Beatty W, et al. A Stem-Cell-Derived Platform Enables Complete Cryptosporidium Development In Vitro and Genetic Tractability. Cell Host Microbe. 2019;: pubmed 出版商
|
Nguyen L, Spitzhorn L, Adjaye J. Constructing an Isogenic 3D Human Nephrogenic Progenitor Cell Model Composed of Endothelial, Mesenchymal, and SIX2-Positive Renal Progenitor Cells. Stem Cells Int. 2019;2019:3298432 pubmed 出版商
|
Gao X, Nowak Imialek M, Chen X, Chen D, Herrmann D, Ruan D, et al. Establishment of porcine and human expanded potential stem cells. Nat Cell Biol. 2019;21:687-699 pubmed 出版商
|
Rhee H, Shaib A, Rehbach K, Lee C, Seif P, Thomas C, et al. An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons. Cell Rep. 2019;27:2212-2228.e7 pubmed 出版商
|
Meijer M, Rehbach K, Brunner J, Classen J, Lammertse H, van Linge L, et al. A Single-Cell Model for Synaptic Transmission and Plasticity in Human iPSC-Derived Neurons. Cell Rep. 2019;27:2199-2211.e6 pubmed 出版商
|
Hackland J, Shelar P, Sandhu N, Prasad M, Charney R, Gomez G, et al. FGF Modulates the Axial Identity of Trunk hPSC-Derived Neural Crest but Not the Cranial-Trunk Decision. Stem Cell Reports. 2019;12:920-933 pubmed 出版商
|
Celano S, Yco L, Kortus M, Solitro A, Gunaydin H, Scott M, et al. Identification of Kinases Responsible for p53-Dependent Autophagy. iScience. 2019;15:109-118 pubmed 出版商
|
Regier M, Tokar J, Warrick J, Pabon L, Berthier E, Beebe D, et al. User-defined morphogen patterning for directing human cell fate stratification. Sci Rep. 2019;9:6433 pubmed 出版商
|
Genga R, Kernfeld E, Parsi K, Parsons T, Ziller M, Maehr R. Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development. Cell Rep. 2019;27:708-718.e10 pubmed 出版商
|
Mair B, Tomic J, Masud S, Tonge P, Weiss A, Usaj M, et al. Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies. Cell Rep. 2019;27:599-615.e12 pubmed 出版商
|
Ng Blichfeldt J, de Jong T, Kortekaas R, Wu X, Lindner M, Guryev V, et al. TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation. Am J Physiol Lung Cell Mol Physiol. 2019;317:L14-L28 pubmed 出版商
|
Bertero A, Fields P, Ramani V, Bonora G, Yardimci G, Reinecke H, et al. Dynamics of genome reorganization during human cardiogenesis reveal an RBM20-dependent splicing factory. Nat Commun. 2019;10:1538 pubmed 出版商
|
Lee Y, Hamann J, Pellegrino M, Durgan J, Domart M, Collinson L, et al. Entosis Controls a Developmental Cell Clearance in C. elegans. Cell Rep. 2019;26:3212-3220.e4 pubmed 出版商
|
Vila O, Uzel S, Ma S, Williams D, Pak J, Kamm R, et al. Quantification of human neuromuscular function through optogenetics. Theranostics. 2019;9:1232-1246 pubmed 出版商
|
Yin J, Zhang L, Ma N, Wang Y, Lee G, Hou X, et al. Chemical Conversion of Human Fetal Astrocytes into Neurons through Modulation of Multiple Signaling Pathways. Stem Cell Reports. 2019;12:488-501 pubmed 出版商
|
Larraufie P, Roberts G, McGavigan A, Kay R, Li J, Leiter A, et al. Important Role of the GLP-1 Axis for Glucose Homeostasis after Bariatric Surgery. Cell Rep. 2019;26:1399-1408.e6 pubmed 出版商
|
Georgouli M, Herraiz C, Crosas Molist E, Fanshawe B, Maiques O, Perdrix A, et al. Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment. Cell. 2019;176:757-774.e23 pubmed 出版商
|
Li M, Keenan C, Lopez Campos G, Mangum J, Chen Q, Prodanovic D, et al. A Non-canonical Pathway with Potential for Safer Modulation of Transforming Growth Factor-β1 in Steroid-Resistant Airway Diseases. iScience. 2019;12:232-246 pubmed 出版商
|
Zhuang Y, Ly R, Frazier C, Yu J, Qin S, Fan X, et al. The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer. Cancer Metab. 2019;7:1 pubmed 出版商
|
Frith T, Tsakiridis A. Efficient Generation of Trunk Neural Crest and Sympathetic Neurons from Human Pluripotent Stem Cells Via a Neuromesodermal Axial Progenitor Intermediate. Curr Protoc Stem Cell Biol. 2019;49:e81 pubmed 出版商
|
Ervin E, Pook M, Teino I, Kasuk V, Trei A, Pooga M, et al. Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14. Stem Cell Res Ther. 2019;10:43 pubmed 出版商
|
Montel Hagen A, Seet C, Li S, Chick B, Zhu Y, Chang P, et al. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2019;24:376-389.e8 pubmed 出版商
|
Wang X, Liao T, Wan C, Yang X, Zhao J, Fu R, et al. Efficient generation of human primordial germ cell-like cells from pluripotent stem cells in a methylcellulose-based 3D system at large scale. Peerj. 2019;6:e6143 pubmed 出版商
|
Ranganathan S, Doucet M, Grassel C, Delaine Elias B, Zachos N, Barry E. Evaluating Shigella flexneri Pathogenesis in the Human Enteroid Model. Infect Immun. 2019;87: pubmed 出版商
|
Lang C, Campbell K, Ryan B, Carling P, Attar M, Vowles J, et al. Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes. Cell Stem Cell. 2019;24:93-106.e6 pubmed 出版商
|
Maguire J, Cardenas Diaz F, Gadue P, French D. Highly Efficient CRISPR-Cas9-Mediated Genome Editing in Human Pluripotent Stem Cells. Curr Protoc Stem Cell Biol. 2019;48:e64 pubmed 出版商
|
Martin Gallausiaux C, Larraufie P, Jarry A, Béguet Crespel F, Marinelli L, Ledue F, et al. Butyrate Produced by Commensal Bacteria Down-Regulates Indolamine 2,3-Dioxygenase 1 (IDO-1) Expression via a Dual Mechanism in Human Intestinal Epithelial Cells. Front Immunol. 2018;9:2838 pubmed 出版商
|
Delpiano L, Thomas J, Yates A, Rice S, Gray M, Saint Criq V. Esomeprazole Increases Airway Surface Liquid pH in Primary Cystic Fibrosis Epithelial Cells. Front Pharmacol. 2018;9:1462 pubmed 出版商
|
Ackermann M, Kempf H, Hetzel M, Hesse C, Hashtchin A, Brinkert K, et al. Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections. Nat Commun. 2018;9:5088 pubmed 出版商
|
Schaffer T, Smith J, Cook E, Phan T, Margolis S. PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5. Cell Rep. 2018;25:2470-2483.e8 pubmed 出版商
|
Pitha I, Oglesby E, Chow A, Kimball E, Pease M, Schaub J, et al. Rho-Kinase Inhibition Reduces Myofibroblast Differentiation and Proliferation of Scleral Fibroblasts Induced by Transforming Growth Factor β and Experimental Glaucoma. Transl Vis Sci Technol. 2018;7:6 pubmed 出版商
|
Ford M, Yeyati P, Mali G, Keighren M, Waddell S, Mjoseng H, et al. A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice. Dev Cell. 2018;47:509-523.e5 pubmed 出版商
|
Sharma A, McKeithan W, Serrano R, Kitani T, Burridge P, Del Alamo J, et al. Use of human induced pluripotent stem cell-derived cardiomyocytes to assess drug cardiotoxicity. Nat Protoc. 2018;13:3018-3041 pubmed 出版商
|
Pirie E, Ray S, Pan C, Fu W, Powers A, Polikoff D, et al. Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a constrained ethyl antisense oligonucleotide targeting Malat1. PLoS Genet. 2018;14:e1007732 pubmed 出版商
|
McKown E, DeAguero J, Canan B, Kilic A, Zhu Y, Janssen P, et al. Impaired adhesion of induced pluripotent stem cell-derived cardiac progenitor cells (iPSC-CPCs) to isolated extracellular matrix from failing hearts. Heliyon. 2018;4:e00870 pubmed 出版商
|
Mehta S, Tom C, Wang Y, Bresee C, Rushton D, Mathkar P, et al. Human Huntington's Disease iPSC-Derived Cortical Neurons Display Altered Transcriptomics, Morphology, and Maturation. Cell Rep. 2018;25:1081-1096.e6 pubmed 出版商
|
Tidball A, Swaminathan P, Dang L, Parent J. Generating Loss-of-function iPSC Lines with Combined CRISPR Indel Formation and Reprogramming from Human Fibroblasts. Bio Protoc. 2018;8: pubmed 出版商
|
Sheng C, Jungverdorben J, Wiethoff H, Lin Q, Flitsch L, Eckert D, et al. A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation. Nat Commun. 2018;9:4047 pubmed 出版商
|
Ng Blichfeldt J, Schrik A, Kortekaas R, Noordhoek J, Heijink I, Hiemstra P, et al. Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiation. EBioMedicine. 2018;36:461-474 pubmed 出版商
|
Vu M, Li R, Baskfield A, Lu B, Farkhondeh A, Gorshkov K, et al. Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease. Orphanet J Rare Dis. 2018;13:152 pubmed 出版商
|
McCauley K, Hawkins F, Kotton D. Derivation of Epithelial-Only Airway Organoids from Human Pluripotent Stem Cells. Curr Protoc Stem Cell Biol. 2018;45:e51 pubmed 出版商
|
Gupta N, Susa K, Yoda Y, Bonventre J, Valerius M, Morizane R. CRISPR/Cas9-based Targeted Genome Editing for the Development of Monogenic Diseases Models with Human Pluripotent Stem Cells. Curr Protoc Stem Cell Biol. 2018;45:e50 pubmed 出版商
|
Levardon H, Yonker L, Hurley B, Mou H. Expansion of Airway Basal Cells and Generation of Polarized Epithelium. Bio Protoc. 2018;8: pubmed 出版商
|
Magro Lopez E, Palmer C, Manso J, Liste I, Zambrano A. Effects of lung and airway epithelial maturation cocktail on the structure of lung bud organoids. Stem Cell Res Ther. 2018;9:186 pubmed 出版商
|
Sommer A, Marxreiter F, Krach F, Fadler T, Grosch J, Maroni M, et al. Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease. Cell Stem Cell. 2018;23:123-131.e6 pubmed 出版商
|
Fazakas C, Nagaraj C, Zabini D, Végh A, Marsh L, Wilhelm I, et al. Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension. Front Physiol. 2018;9:537 pubmed 出版商
|
Sharma A, Mücke M, Seidman C. Human Induced Pluripotent Stem Cell Production and Expansion from Blood using a Non-Integrating Viral Reprogramming Vector. Curr Protoc Mol Biol. 2018;122:e58 pubmed 出版商
|
Hepburn L, McHugh A, Fernandes K, Boag G, Proby C, Leigh I, et al. Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity. Oncotarget. 2018;9:23029-23046 pubmed 出版商
|
Medelnik J, Roensch K, Okawa S, del Sol A, Chara O, Mchedlishvili L, et al. Signaling-Dependent Control of Apical Membrane Size and Self-Renewal in Rosette-Stage Human Neuroepithelial Stem Cells. Stem Cell Reports. 2018;: pubmed 出版商
|
McHugh A, Fernandes K, South A, Mellerio J, Salas Alanis J, Proby C, et al. Preclinical comparison of proteasome and ubiquitin E1 enzyme inhibitors in cutaneous squamous cell carcinoma: the identification of mechanisms of differential sensitivity. Oncotarget. 2018;9:20265-20281 pubmed 出版商
|
Ho L, Skiba N, Ullmer C, Rao P. Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2018;59:1969-1984 pubmed 出版商
|
Rath N, Munro J, Cutiongco M, Jagiełło A, Gadegaard N, McGarry L, et al. Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarcinoma Invasion and Tumor Growth. Cancer Res. 2018;78:3321-3336 pubmed 出版商
|
Lynch T, Anderson P, Rotti P, Tyler S, Crooke A, Choi S, et al. Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium. Cell Stem Cell. 2018;22:653-667.e5 pubmed 出版商
|
Sima N, Li R, Huang W, Xu M, Beers J, Zou J, et al. Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses. Orphanet J Rare Dis. 2018;13:54 pubmed 出版商
|
Asumda F, Hatzistergos K, Dykxhoorn D, Jakubski S, Edwards J, Thomas E, et al. Differentiation of hepatocyte-like cells from human pluripotent stem cells using small molecules. Differentiation. 2018;101:16-24 pubmed 出版商
|
Ronaldson Bouchard K, Ma S, Yeager K, Chen T, Song L, Sirabella D, et al. Advanced maturation of human cardiac tissue grown from pluripotent stem cells. Nature. 2018;556:239-243 pubmed 出版商
|
Wong V, Picci C, Swift M, Levinson M, Willis D, Langley B. α-Tubulin Acetyltransferase Is a Novel Target Mediating Neurite Growth Inhibitory Effects of Chondroitin Sulfate Proteoglycans and Myelin-Associated Glycoprotein. Eneuro. 2018;5: pubmed 出版商
|
Bantounas I, Ranjzad P, Tengku F, Silajdzic E, Forster D, Asselin M, et al. Generation of Functioning Nephrons by Implanting Human Pluripotent Stem Cell-Derived Kidney Progenitors. Stem Cell Reports. 2018;10:766-779 pubmed 出版商
|
Edwards D, Ngwa V, Wang S, Shiuan E, Brantley Sieders D, Kim L, et al. The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ. Sci Signal. 2017;10: pubmed 出版商
|
Kinarivala N, Patel R, Boustany R, Al Ahmad A, Trippier P. Discovery of Aromatic Carbamates that Confer Neuroprotective Activity by Enhancing Autophagy and Inducing the Anti-Apoptotic Protein B-Cell Lymphoma 2 (Bcl-2). J Med Chem. 2017;: pubmed 出版商
|
Major T, Powers A, Tabar V. Derivation of telencephalic oligodendrocyte progenitors from human pluripotent stem cells. Curr Protoc Stem Cell Biol. 2017;39:1H.10.1-1H.10.23 pubmed 出版商
|
Wang J, Jenjaroenpun P, Bhinge A, Angarica V, del Sol A, Nookaew I, et al. Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons. Genome Res. 2017;27:1783-1794 pubmed 出版商
|
JACOB A, Morley M, Hawkins F, McCauley K, Jean J, Heins H, et al. Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells. Cell Stem Cell. 2017;21:472-488.e10 pubmed 出版商
|
Hubaud A, Regev I, Mahadevan L, Pourquie O. Excitable Dynamics and Yap-Dependent Mechanical Cues Drive the Segmentation Clock. Cell. 2017;171:668-682.e11 pubmed 出版商
|
Shukla V, Rao M, ZHANG H, Beers J, Wangsa D, Wangsa D, et al. ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer. Cancer Res. 2017;77:6267-6281 pubmed 出版商
|
Tchieu J, Zimmer B, Fattahi F, Amin S, Zeltner N, Chen S, et al. A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages. Cell Stem Cell. 2017;21:399-410.e7 pubmed 出版商
|
Sloan S, Darmanis S, Huber N, Khan T, Birey F, Caneda C, et al. Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells. Neuron. 2017;95:779-790.e6 pubmed 出版商
|
Bao X, Lian X, Qian T, Bhute V, Han T, Palecek S. Directed differentiation and long-term maintenance of epicardial cells derived from human pluripotent stem cells under fully defined conditions. Nat Protoc. 2017;12:1890-1900 pubmed 出版商
|
Shi Q, Yang L, Shi W, Wang L, Zhou S, Guan S, et al. The novel cannabinoid receptor GPR55 mediates anxiolytic-like effects in the medial orbital cortex of mice with acute stress. Mol Brain. 2017;10:38 pubmed 出版商
|
Shao Y, Taniguchi K, Townshend R, Miki T, Gumucio D, Fu J. A pluripotent stem cell-based model for post-implantation human amniotic sac development. Nat Commun. 2017;8:208 pubmed 出版商
|
Lee J, Protze S, Laksman Z, Backx P, Keller G. Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations. Cell Stem Cell. 2017;21:179-194.e4 pubmed 出版商
|
Hamann J, Surcel A, Chen R, Teragawa C, Albeck J, Robinson D, et al. Entosis Is Induced by Glucose Starvation. Cell Rep. 2017;20:201-210 pubmed 出版商
|
Aguisanda F, Yeh C, Chen C, Li R, Beers J, Zou J, et al. Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics. Orphanet J Rare Dis. 2017;12:120 pubmed 出版商
|
Vermilyea S, Guthrie S, Meyer M, Smuga Otto K, Braun K, Howden S, et al. Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts. Stem Cells Dev. 2017;26:1225-1235 pubmed 出版商
|
Benedicto I, Lehmann G, Ginsberg M, Nolan D, Bareja R, Elemento O, et al. Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors. Nat Commun. 2017;8:15374 pubmed 出版商
|
Abud E, Ramirez R, Martinez E, Healy L, Nguyen C, Newman S, et al. iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron. 2017;94:278-293.e9 pubmed 出版商
|
Tischfield D, Kim J, Anderson S. Atypical PKC and Notch Inhibition Differentially Modulate Cortical Interneuron Subclass Fate from Embryonic Stem Cells. Stem Cell Reports. 2017;8:1135-1143 pubmed 出版商
|
Yang Y, Liu B, Xu J, Wang J, Wu J, Shi C, et al. Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell. 2017;169:243-257.e25 pubmed 出版商
|
McCauley K, Hawkins F, Serra M, Thomas D, JACOB A, Kotton D. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling. Cell Stem Cell. 2017;20:844-857.e6 pubmed 出版商
|
Xi H, Fujiwara W, Gonzalez K, Jan M, Liebscher S, Van Handel B, et al. In Vivo Human Somitogenesis Guides Somite Development from hPSCs. Cell Rep. 2017;18:1573-1585 pubmed 出版商
|
Hall M, Murray C, Valdez M, Perantoni A. Mesoderm-specific Stat3 deletion affects expression of Sox9 yielding Sox9-dependent phenotypes. PLoS Genet. 2017;13:e1006610 pubmed 出版商
|
Subramanian L, Bershteyn M, Paredes M, Kriegstein A. Dynamic behaviour of human neuroepithelial cells in the developing forebrain. Nat Commun. 2017;8:14167 pubmed 出版商
|
Bershteyn M, Nowakowski T, Pollen A, Di Lullo E, Nene A, Wynshaw Boris A, et al. Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia. Cell Stem Cell. 2017;20:435-449.e4 pubmed 出版商
|
Mohapatra B, Zutshi N, An W, Goetz B, Arya P, Bielecki T, et al. An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance. Development. 2017;144:1072-1086 pubmed 出版商
|
Rath N, Morton J, Julian L, Helbig L, Kadir S, McGhee E, et al. ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth. EMBO Mol Med. 2017;9:198-218 pubmed 出版商
|
Morizane R, Bonventre J. Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells. Nat Protoc. 2017;12:195-207 pubmed 出版商
|
Palpant N, Pabon L, Friedman C, Roberts M, Hadland B, Zaunbrecher R, et al. Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells. Nat Protoc. 2017;12:15-31 pubmed 出版商
|
Bonan S, Albrengues J, Grasset E, Kuzet S, Nottet N, Bourget I, et al. Membrane-bound ICAM-1 contributes to the onset of proinvasive tumor stroma by controlling acto-myosin contractility in carcinoma-associated fibroblasts. Oncotarget. 2017;8:1304-1320 pubmed 出版商
|
Ferland D, Darios E, Neubig R, Sjögren B, Truong N, Torres R, et al. Chemerin-induced arterial contraction is Gi- and calcium-dependent. Vascul Pharmacol. 2017;88:30-41 pubmed 出版商
|
Wilson H, Faubion M, Hjortness M, Palecek S, Shusta E. Cryopreservation of Brain Endothelial Cells Derived from Human Induced Pluripotent Stem Cells Is Enhanced by Rho-Associated Coiled Coil-Containing Kinase Inhibition. Tissue Eng Part C Methods. 2016;22:1085-1094 pubmed
|
Zeltner N, Fattahi F, Dubois N, Saurat N, Lafaille F, Shang L, et al. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia. Nat Med. 2016;22:1421-1427 pubmed 出版商
|
Rath N, Kalna G, Clark W, Olson M. ROCK signalling induced gene expression changes in mouse pancreatic ductal adenocarcinoma cells. Sci Data. 2016;3:160101 pubmed 出版商
|
Jardé T, Lloyd Lewis B, Thomas M, Kendrick H, Melchor L, Bougaret L, et al. Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids. Nat Commun. 2016;7:13207 pubmed 出版商
|
La Manno G, Gyllborg D, Codeluppi S, Nishimura K, Salto C, Zeisel A, et al. Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells. Cell. 2016;167:566-580.e19 pubmed 出版商
|
Pei S, Liu L, Zhong Z, Wang H, Lin S, Shang J. Risk of prenatal depression and stress treatment: alteration on serotonin system of offspring through exposure to Fluoxetine. Sci Rep. 2016;6:33822 pubmed 出版商
|
Mulay A, Akram K, Williams D, Armes H, Russell C, Hood D, et al. An in vitro model of murine middle ear epithelium. Dis Model Mech. 2016;9:1405-1417 pubmed
|
Borgs L, Peyre E, Alix P, Hanon K, Grobarczyk B, Godin J, et al. Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Sci Rep. 2016;6:33377 pubmed 出版商
|
Chal J, Al Tanoury Z, Hestin M, Gobert B, Aivio S, Hick A, et al. Generation of human muscle fibers and satellite-like cells from human pluripotent stem cells in vitro. Nat Protoc. 2016;11:1833-50 pubmed 出版商
|
Long Y, Xu M, Li R, Dai S, Beers J, Chen G, et al. Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A. Stem Cells Transl Med. 2016;5:1644-1655 pubmed
|
Koopmans T, Kumawat K, Halayko A, Gosens R. Regulation of actin dynamics by WNT-5A: implications for human airway smooth muscle contraction. Sci Rep. 2016;6:30676 pubmed 出版商
|
Mou H, Vinarsky V, Tata P, Brazauskas K, Choi S, Crooke A, et al. Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells. Cell Stem Cell. 2016;19:217-231 pubmed 出版商
|
Tidball A, Neely M, Chamberlin R, Aboud A, Kumar K, Han B, et al. Genomic Instability Associated with p53 Knockdown in the Generation of Huntington's Disease Human Induced Pluripotent Stem Cells. PLoS ONE. 2016;11:e0150372 pubmed 出版商
|
Balcioglu H, van de Water B, Danen E. Tumor-induced remote ECM network orientation steers angiogenesis. Sci Rep. 2016;6:22580 pubmed 出版商
|
Kellner Y, Fricke S, Kramer S, Iobbi C, Wierenga C, Schwab M, et al. Nogo-A controls structural plasticity at dendritic spines by rapidly modulating actin dynamics. Hippocampus. 2016;26:816-31 pubmed 出版商
|
Yu J, Fernandez Gonzalez R. Local mechanical forces promote polarized junctional assembly and axis elongation in Drosophila. elife. 2016;5: pubmed 出版商
|
Guye P, Ebrahimkhani M, Kipniss N, Velazquez J, Schoenfeld E, Kiani S, et al. Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6. Nat Commun. 2016;7:10243 pubmed 出版商
|
Hien T, TurczyÅ„ska K, Dahan D, Ekman M, Grossi M, Sjögren J, et al. Elevated Glucose Levels Promote Contractile and Cytoskeletal Gene Expression in Vascular Smooth Muscle via Rho/Protein Kinase C and Actin Polymerization. J Biol Chem. 2016;291:3552-68 pubmed 出版商
|
Foulke Abel J, In J, Yin J, Zachos N, Kovbasnjuk O, Estes M, et al. Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology. Gastroenterology. 2016;150:638-649.e8 pubmed 出版商
|
Fernandes S, Chong J, Paige S, Iwata M, Torok Storb B, Keller G, et al. Comparison of Human Embryonic Stem Cell-Derived Cardiomyocytes, Cardiovascular Progenitors, and Bone Marrow Mononuclear Cells for Cardiac Repair. Stem Cell Reports. 2015;5:753-62 pubmed
|
Sakaguchi H, Kadoshima T, Soen M, Narii N, Ishida Y, Ohgushi M, et al. Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue. Nat Commun. 2015;6:8896 pubmed 出版商
|
Chen R, Zhang G, Garfield S, Shi Y, Chen K, Robey P, et al. Variations in Glycogen Synthesis in Human Pluripotent Stem Cells with Altered Pluripotent States. PLoS ONE. 2015;10:e0142554 pubmed 出版商
|
Arbab M, Srinivasan S, Hashimoto T, Geijsen N, Sherwood R. Cloning-free CRISPR. Stem Cell Reports. 2015;5:908-17 pubmed 出版商
|
Stebbins M, Wilson H, Canfield S, Qian T, Palecek S, Shusta E. Differentiation and characterization of human pluripotent stem cell-derived brain microvascular endothelial cells. Methods. 2016;101:93-102 pubmed 出版商
|
Maharam E, Yaport M, Villanueva N, Akinyibi T, Laudier D, He Z, et al. Rho/Rock signal transduction pathway is required for MSC tenogenic differentiation. Bone Res. 2015;3:15015 pubmed 出版商
|
Ziv O, Zaritsky A, Yaffe Y, Mutukula N, Edri R, Elkabetz Y. Quantitative Live Imaging of Human Embryonic Stem Cell Derived Neural Rosettes Reveals Structure-Function Dynamics Coupled to Cortical Development. PLoS Comput Biol. 2015;11:e1004453 pubmed 出版商
|
Morizane R, Lam A, Freedman B, Kishi S, Valerius M, Bonventre J. Nephron organoids derived from human pluripotent stem cells model kidney development and injury. Nat Biotechnol. 2015;33:1193-200 pubmed
|
Tai I, Wang Y, Chen C, Chuang S, Chang J, Ho M. Simvastatin enhances Rho/actin/cell rigidity pathway contributing to mesenchymal stem cells' osteogenic differentiation. Int J Nanomedicine. 2015;10:5881-94 pubmed 出版商
|
Davies J, Santaolalla R, von Furstenberg R, Henning S, Abreu M. The Viral Mimetic Polyinosinic:Polycytidylic Acid Alters the Growth Characteristics of Small Intestinal and Colonic Crypt Cultures. PLoS ONE. 2015;10:e0138531 pubmed 出版商
|
Jönsson M, Nelander Wahlestedt J, Akerblom M, Kirkeby A, Malmevik J, Brattaas P, et al. Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor. Development. 2015;142:3166-77 pubmed 出版商
|
Madsen C, Pedersen J, Venning F, Singh L, Moeendarbary E, Charras G, et al. Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis. EMBO Rep. 2015;16:1394-408 pubmed 出版商
|
Rempel E, Hoelting L, Waldmann T, Balmer N, Schildknecht S, Grinberg M, et al. A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol. 2015;89:1599-618 pubmed 出版商
|
Iovino M, Agathou S, González Rueda A, Del Castillo Velasco Herrera M, Borroni B, Alberici A, et al. Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations. Brain. 2015;138:3345-59 pubmed 出版商
|
Serra N, Rosales R, Masana L, Vallvé J. Simvastatin Increases Fibulin-2 Expression in Human Coronary Artery Smooth Muscle Cells via RhoA/Rho-Kinase Signaling Pathway Inhibition. PLoS ONE. 2015;10:e0133875 pubmed 出版商
|
Gjorevski N, Piotrowski A, Varner V, Nelson C. Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices. Sci Rep. 2015;5:11458 pubmed 出版商
|
Lee E, Kurokawa Y, Tu R, George S, Khine M. Machine learning plus optical flow: a simple and sensitive method to detect cardioactive drugs. Sci Rep. 2015;5:11817 pubmed 出版商
|
Abraham S, Scarcia M, Bagshaw R, McMahon K, Grant G, Harvey T, et al. A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis. Nat Commun. 2015;6:7286 pubmed 出版商
|
Gallego Romero I, Pavlovic B, Hernando Herraez I, Zhou X, WARD M, Banovich N, et al. A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics. elife. 2015;4:e07103 pubmed 出版商
|
Su C, Chen C, Ho W, Hu F, Lee S, Wang I. Phenotypes of trypsin- and collagenase-prepared bovine corneal endothelial cells in the presence of a selective Rho kinase inhibitor, Y-27632. Mol Vis. 2015;21:633-43 pubmed
|
Härmä V, Haavikko R, Virtanen J, Ahonen I, Schukov H, Alakurtti S, et al. Optimization of Invasion-Specific Effects of Betulin Derivatives on Prostate Cancer Cells through Lead Development. PLoS ONE. 2015;10:e0126111 pubmed 出版商
|
Lee H, Ji S, Park S, Choung H, Choi Y, Lee H, et al. Odontogenic Ameloblast-associated Protein (ODAM) Mediates Junctional Epithelium Attachment to Teeth via Integrin-ODAM-Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5)-RhoA Signaling. J Biol Chem. 2015;290:14740-53 pubmed 出版商
|
Tyson J, Goldberg E, Maroof A, Xu Q, Petros T, Anderson S. Duration of culture and sonic hedgehog signaling differentially specify PV versus SST cortical interneuron fates from embryonic stem cells. Development. 2015;142:1267-78 pubmed 出版商
|
Edri R, Yaffe Y, Ziller M, Mutukula N, Volkman R, David E, et al. Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitors. Nat Commun. 2015;6:6500 pubmed 出版商
|
Höfner T, Eisen C, Klein C, Rigo Watermeier T, Goeppinger S, Jauch A, et al. Defined conditions for the isolation and expansion of basal prostate progenitor cells of mouse and human origin. Stem Cell Reports. 2015;4:503-18 pubmed 出版商
|
Chaudhuri O, Gu L, Darnell M, Klumpers D, Bencherif S, Weaver J, et al. Substrate stress relaxation regulates cell spreading. Nat Commun. 2015;6:6364 pubmed 出版商
|
Lachmann N, Ackermann M, Frenzel E, Liebhaber S, Brennig S, Happle C, et al. Large-scale hematopoietic differentiation of human induced pluripotent stem cells provides granulocytes or macrophages for cell replacement therapies. Stem Cell Reports. 2015;4:282-96 pubmed 出版商
|
Ruprecht V, Wieser S, Callan Jones A, Smutny M, Morita H, Sako K, et al. Cortical contractility triggers a stochastic switch to fast amoeboid cell motility. Cell. 2015;160:673-685 pubmed 出版商
|
Balcioglu H, van Hoorn H, Donato D, Schmidt T, Danen E. The integrin expression profile modulates orientation and dynamics of force transmission at cell-matrix adhesions. J Cell Sci. 2015;128:1316-26 pubmed 出版商
|
Piao J, Major T, Auyeung G, Policarpio E, Menon J, Droms L, et al. Human embryonic stem cell-derived oligodendrocyte progenitors remyelinate the brain and rescue behavioral deficits following radiation. Cell Stem Cell. 2015;16:198-210 pubmed 出版商
|
Vergara D, De Domenico S, Maffia M, Piro G, Di Sansebastiano G. Transgenic plants as low-cost platform for chemotherapeutic drugs screening. Int J Mol Sci. 2015;16:2174-86 pubmed 出版商
|
Luzzani C, Neiman G, Garate X, Questa M, Solari C, Fernandez Espinosa D, et al. A therapy-grade protocol for differentiation of pluripotent stem cells into mesenchymal stem cells using platelet lysate as supplement. Stem Cell Res Ther. 2015;6:6 pubmed 出版商
|
Cossette S, Gastonguay A, Bao X, Lerch Gaggl A, Zhong L, Harmann L, et al. Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism. Biol Open. 2014;4:48-61 pubmed 出版商
|
Aubdool A, Graepel R, Kodji X, Alawi K, Bodkin J, Srivastava S, et al. TRPA1 is essential for the vascular response to environmental cold exposure. Nat Commun. 2014;5:5732 pubmed 出版商
|
Pattabiraman P, Rinkoski T, Poeschla E, Proia A, Challa P, Rao P. RhoA GTPase-induced ocular hypertension in a rodent model is associated with increased fibrogenic activity in the trabecular meshwork. Am J Pathol. 2015;185:496-512 pubmed 出版商
|
Wrighton P, Klim J, Hernandez B, Koonce C, Kamp T, Kiessling L. Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins. Proc Natl Acad Sci U S A. 2014;111:18126-31 pubmed 出版商
|
Liu W, Chen G. Cryopreservation of human pluripotent stem cells in defined medium. Curr Protoc Stem Cell Biol. 2014;31:1C.17.1-13 pubmed 出版商
|
Sun Q, Luo T, Ren Y, Florey O, Shirasawa S, Sasazuki T, et al. Competition between human cells by entosis. Cell Res. 2014;24:1299-310 pubmed 出版商
|
Sun Q, Cibas E, Huang H, Hodgson L, Overholtzer M. Induction of entosis by epithelial cadherin expression. Cell Res. 2014;24:1288-98 pubmed 出版商
|
Shelton M, Metz J, Liu J, Carpenedo R, Demers S, Stanford W, et al. Derivation and expansion of PAX7-positive muscle progenitors from human and mouse embryonic stem cells. Stem Cell Reports. 2014;3:516-29 pubmed 出版商
|
Wile B, Ban K, Yoon Y, Bao G. Molecular beacon-enabled purification of living cells by targeting cell type-specific mRNAs. Nat Protoc. 2014;9:2411-24 pubmed 出版商
|
Pavlov T, Levchenko V, Staruschenko A. Role of Rho GDP dissociation inhibitor α in control of epithelial sodium channel (ENaC)-mediated sodium reabsorption. J Biol Chem. 2014;289:28651-9 pubmed 出版商
|
Choi D, Stark D, Raphael R, Wen J, Su J, Zhou X, et al. SDF-1α stiffens myeloma bone marrow mesenchymal stromal cells through the activation of RhoA-ROCK-Myosin II. Int J Cancer. 2015;136:E219-29 pubmed 出版商
|
Orgaz J, Pandya P, Dalmeida R, Karagiannis P, Sanchez Laorden B, Viros A, et al. Diverse matrix metalloproteinase functions regulate cancer amoeboid migration. Nat Commun. 2014;5:4255 pubmed 出版商
|
Williams L, Mukherjee D, Fisher M, Reyes Aldasoro C, Akerman S, Kanthou C, et al. An in vivo role for Rho kinase activation in the tumour vascular disrupting activity of combretastatin A-4 3-O-phosphate. Br J Pharmacol. 2014;171:4902-13 pubmed 出版商
|
Feng X, Degese M, Iglesias Bartolomé R, Vaque J, Molinolo A, Rodrigues M, et al. Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry. Cancer Cell. 2014;25:831-45 pubmed 出版商
|
Mich J, Signer R, Nakada D, Pineda A, Burgess R, Vue T, et al. Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain. elife. 2014;3:e02669 pubmed 出版商
|
Luo Y, Rao M, Zou J. Generation of GFP Reporter Human Induced Pluripotent Stem Cells Using AAVS1 Safe Harbor Transcription Activator-Like Effector Nuclease. Curr Protoc Stem Cell Biol. 2014;29:5A.7.1-18 pubmed 出版商
|
Dickover M, Hegarty J, Ly K, Lopez D, Yang H, Zhang R, et al. The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis. Dev Biol. 2014;389:182-91 pubmed 出版商
|
Matsumoto Y, Hayashi Y, Schlieve C, Ikeya M, Kim H, Nguyen T, et al. Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation. Orphanet J Rare Dis. 2013;8:190 pubmed 出版商
|
Huang S, Islam M, O NEILL J, Hu Z, Yang Y, Chen Y, et al. Efficient generation of lung and airway epithelial cells from human pluripotent stem cells. Nat Biotechnol. 2014;32:84-91 pubmed 出版商
|
Moon C, VanDussen K, Miyoshi H, Stappenbeck T. Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis. Mucosal Immunol. 2014;7:818-28 pubmed 出版商
|
Gafni O, Weinberger L, Mansour A, Manor Y, Chomsky E, Ben Yosef D, et al. Derivation of novel human ground state naive pluripotent stem cells. Nature. 2013;504:282-6 pubmed 出版商
|
Kameoka S, Babiarz J, Kolaja K, Chiao E. A high-throughput screen for teratogens using human pluripotent stem cells. Toxicol Sci. 2014;137:76-90 pubmed 出版商
|
Kirschstein T, Protzel C, Porath K, Sellmann T, Köhling R, Hakenberg O. Age-dependent contribution of Rho kinase in carbachol-induced contraction of human detrusor smooth muscle in vitro. Acta Pharmacol Sin. 2014;35:74-81 pubmed 出版商
|
McNary S, Athanasiou K, Reddi A. Transforming growth factor ?-induced superficial zone protein accumulation in the surface zone of articular cartilage is dependent on the cytoskeleton. Tissue Eng Part A. 2014;20:921-9 pubmed 出版商
|
Krajcovic M, Krishna S, Akkari L, Joyce J, Overholtzer M. mTOR regulates phagosome and entotic vacuole fission. Mol Biol Cell. 2013;24:3736-45 pubmed 出版商
|
Crompton L, Byrne M, Taylor H, Kerrigan T, Bru Mercier G, Badger J, et al. Stepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signaling. Stem Cell Res. 2013;11:1206-21 pubmed 出版商
|
Keimpema E, Zheng K, Barde S, Berghuis P, Dobszay M, Schnell R, et al. GABAergic terminals are a source of galanin to modulate cholinergic neuron development in the neonatal forebrain. Cereb Cortex. 2014;24:3277-88 pubmed 出版商
|
Smith D, Kiba A, Zong Y, Witte O. Interleukin-6 and oncostatin-M synergize with the PI3K/AKT pathway to promote aggressive prostate malignancy in mouse and human tissues. Mol Cancer Res. 2013;11:1159-65 pubmed 出版商
|
Hutchins B, Klenke U, Wray S. Calcium release-dependent actin flow in the leading process mediates axophilic migration. J Neurosci. 2013;33:11361-71 pubmed 出版商
|
Goldspink D, Gadsby J, Bellett G, Keynton J, Tyrrell B, Lund E, et al. The microtubule end-binding protein EB2 is a central regulator of microtubule reorganisation in apico-basal epithelial differentiation. J Cell Sci. 2013;126:4000-14 pubmed 出版商
|
Zeller K, Riaz A, Sarve H, Li J, Tengholm A, Johansson S. The role of mechanical force and ROS in integrin-dependent signals. PLoS ONE. 2013;8:e64897 pubmed 出版商
|
Calvo F, Ege N, Grande García A, Hooper S, Jenkins R, Chaudhry S, et al. Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts. Nat Cell Biol. 2013;15:637-46 pubmed 出版商
|
Zhu W, Nelson C. PI3K regulates branch initiation and extension of cultured mammary epithelia via Akt and Rac1 respectively. Dev Biol. 2013;379:235-45 pubmed 出版商
|
Lu J, Liu H, Huang C, Chen H, Du Z, Liu Y, et al. Generation of integration-free and region-specific neural progenitors from primate fibroblasts. Cell Rep. 2013;3:1580-91 pubmed 出版商
|
Li A, Chen M, Jiang T, Wu P, Nie Q, Widelitz R, et al. Shaping organs by a wingless-int/Notch/nonmuscle myosin module which orients feather bud elongation. Proc Natl Acad Sci U S A. 2013;110:E1452-61 pubmed 出版商
|
Lazzeroni G, Benicchi T, Heitz F, Magnoni L, Diamanti D, Rossini L, et al. A phenotypic screening assay for modulators of huntingtin-induced transcriptional dysregulation. J Biomol Screen. 2013;18:984-96 pubmed 出版商
|
Barthwal M, Anzinger J, Xu Q, Bohnacker T, Wymann M, Kruth H. Fluid-phase pinocytosis of native low density lipoprotein promotes murine M-CSF differentiated macrophage foam cell formation. PLoS ONE. 2013;8:e58054 pubmed 出版商
|
Pol S, Lang J, O Bara M, Cimato T, McCallion A, Sim F. Sox10-MCS5 enhancer dynamically tracks human oligodendrocyte progenitor fate. Exp Neurol. 2013;247:694-702 pubmed 出版商
|
Lin G, Cohen D, Desai R, Breckenridge M, Gao L, Humphries M, et al. Activation of beta 1 but not beta 3 integrin increases cell traction forces. FEBS Lett. 2013;587:763-9 pubmed 出版商
|
Kirkeby A, Nelander J, Parmar M. Generating regionalized neuronal cells from pluripotency, a step-by-step protocol. Front Cell Neurosci. 2012;6:64 pubmed 出版商
|
Lian X, Zhang J, Azarin S, Zhu K, Hazeltine L, Bao X, et al. Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/?-catenin signaling under fully defined conditions. Nat Protoc. 2013;8:162-75 pubmed 出版商
|
Beers J, Gulbranson D, George N, Siniscalchi L, Jones J, Thomson J, et al. Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions. Nat Protoc. 2012;7:2029-40 pubmed 出版商
|
Walker B, Ji S, Jaffrey S. Intra-axonal translation of RhoA promotes axon growth inhibition by CSPG. J Neurosci. 2012;32:14442-7 pubmed 出版商
|
Hannan J, Albersen M, Kutlu O, Gratzke C, Stief C, Burnett A, et al. Inhibition of Rho-kinase improves erectile function, increases nitric oxide signaling and decreases penile apoptosis in a rat model of cavernous nerve injury. J Urol. 2013;189:1155-61 pubmed 出版商
|
Paige S, Thomas S, Stoick Cooper C, Wang H, Maves L, Sandstrom R, et al. A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development. Cell. 2012;151:221-32 pubmed 出版商
|
Roller D, Axelrod M, Capaldo B, Jensen K, Mackey A, Weber M, et al. Synthetic lethal screening with small-molecule inhibitors provides a pathway to rational combination therapies for melanoma. Mol Cancer Ther. 2012;11:2505-15 pubmed 出版商
|
Harel S, Tu E, Weisberg S, Esquilin M, Chambers S, Liu B, et al. ZFX controls the self-renewal of human embryonic stem cells. PLoS ONE. 2012;7:e42302 pubmed 出版商
|
Neely M, Litt M, Tidball A, Li G, Aboud A, Hopkins C, et al. DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction. ACS Chem Neurosci. 2012;3:482-91 pubmed 出版商
|
Gupta N, Davis C, Nelson J, Young J, Alkayed N. Soluble epoxide hydrolase: sex differences and role in endothelial cell survival. Arterioscler Thromb Vasc Biol. 2012;32:1936-42 pubmed 出版商
|
Goulopoulou S, Hannan J, Matsumoto T, Webb R. Pregnancy reduces RhoA/Rho kinase and protein kinase C signaling pathways downstream of thromboxane receptor activation in the rat uterine artery. Am J Physiol Heart Circ Physiol. 2012;302:H2477-88 pubmed 出版商
|
Guo W, Keckesova Z, Donaher J, Shibue T, Tischler V, Reinhardt F, et al. Slug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012;148:1015-28 pubmed 出版商
|
Loubet D, Dakowski C, Pietri M, Pradines E, Bernard S, Callebert J, et al. Neuritogenesis: the prion protein controls ?1 integrin signaling activity. FASEB J. 2012;26:678-90 pubmed 出版商
|
Lee S, Kim D, Kim K, Myung S, Lee M. The Relaxing Effect of ?-Defensin 1 on the Adrenergic Responses of Rat Bladder. Korean J Physiol Pharmacol. 2011;15:143-7 pubmed 出版商
|
Sherwood R, Maehr R, Mazzoni E, Melton D. Wnt signaling specifies and patterns intestinal endoderm. Mech Dev. 2011;128:387-400 pubmed 出版商
|
Abreu Blanco M, Verboon J, Parkhurst S. Cell wound repair in Drosophila occurs through three distinct phases of membrane and cytoskeletal remodeling. J Cell Biol. 2011;193:455-64 pubmed 出版商
|
Yang M, Reich D, Chen C. Measurement and analysis of traction force dynamics in response to vasoactive agonists. Integr Biol (Camb). 2011;3:663-74 pubmed 出版商
|
Stiegler N, Krug A, Matt F, Leist M. Assessment of chemical-induced impairment of human neurite outgrowth by multiparametric live cell imaging in high-density cultures. Toxicol Sci. 2011;121:73-87 pubmed 出版商
|
Vallenius T, Vaahtomeri K, Kovac B, Osiceanu A, Viljanen M, Makela T. An association between NUAK2 and MRIP reveals a novel mechanism for regulation of actin stress fibers. J Cell Sci. 2011;124:384-93 pubmed 出版商
|
Rodrigues Díez R, Rodrígues Díez R, Lavoz C, Rayego Mateos S, Civantos E, Rodriguez Vita J, et al. Statins inhibit angiotensin II/Smad pathway and related vascular fibrosis, by a TGF-?-independent process. PLoS ONE. 2010;5:e14145 pubmed 出版商
|
Kaur S, Leszczynska K, Abraham S, Scarcia M, Hiltbrunner S, Marshall C, et al. RhoJ/TCL regulates endothelial motility and tube formation and modulates actomyosin contractility and focal adhesion numbers. Arterioscler Thromb Vasc Biol. 2011;31:657-64 pubmed 出版商
|
Kim J, Wu Q, Zhang Y, Wiens K, Huang Y, Rubin N, et al. PDGF signaling is required for epicardial function and blood vessel formation in regenerating zebrafish hearts. Proc Natl Acad Sci U S A. 2010;107:17206-10 pubmed 出版商
|
Simões S, Blankenship J, Weitz O, Farrell D, Tamada M, Fernandez Gonzalez R, et al. Rho-kinase directs Bazooka/Par-3 planar polarity during Drosophila axis elongation. Dev Cell. 2010;19:377-88 pubmed 出版商
|
Gjorevski N, Nelson C. Endogenous patterns of mechanical stress are required for branching morphogenesis. Integr Biol (Camb). 2010;2:424-34 pubmed 出版商
|
Cao J, Crest J, Fasulo B, Sullivan W. Cortical actin dynamics facilitate early-stage centrosome separation. Curr Biol. 2010;20:770-6 pubmed 出版商
|
Gomez E, Chen Q, Gjorevski N, Nelson C. Tissue geometry patterns epithelial-mesenchymal transition via intercellular mechanotransduction. J Cell Biochem. 2010;110:44-51 pubmed 出版商
|
Giampieri S, Manning C, Hooper S, Jones L, Hill C, Sahai E. Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility. Nat Cell Biol. 2009;11:1287-96 pubmed 出版商
|
da Silva Santos J, Chiao C, Leite R, Webb R. The Rho-A/Rho-kinase pathway is up-regulated but remains inhibited by cyclic guanosine monophosphate-dependent mechanisms during endotoxemia in small mesenteric arteries. Crit Care Med. 2009;37:1716-23 pubmed 出版商
|
Desai R, Gao L, Raghavan S, Liu W, Chen C. Cell polarity triggered by cell-cell adhesion via E-cadherin. J Cell Sci. 2009;122:905-11 pubmed 出版商
|
Rodriguez Vita J, Sánchez Galán E, Santamaria B, Sanchez Lopez E, Rodrígues Díez R, Blanco Colio L, et al. Essential role of TGF-beta/Smad pathway on statin dependent vascular smooth muscle cell regulation. PLoS ONE. 2008;3:e3959 pubmed 出版商
|
Ruiz S, Chen C. Emergence of patterned stem cell differentiation within multicellular structures. Stem Cells. 2008;26:2921-7 pubmed 出版商
|
Inan S, Buyukafsar K. Antiepileptic effects of two Rho-kinase inhibitors, Y-27632 and fasudil, in mice. Br J Pharmacol. 2008;155:44-51 pubmed 出版商
|
Bhadriraju K, Elliott J, Nguyen M, Plant A. Quantifying myosin light chain phosphorylation in single adherent cells with automated fluorescence microscopy. BMC Cell Biol. 2007;8:43 pubmed
|
Schaafsma D, Gosens R, Ris J, Zaagsma J, Meurs H, Nelemans S. Insulin induces airway smooth muscle contraction. Br J Pharmacol. 2007;150:136-42 pubmed
|
Wyckoff J, Pinner S, Gschmeissner S, Condeelis J, Sahai E. ROCK- and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo. Curr Biol. 2006;16:1515-23 pubmed
|
Munoz Garcia B, Martin Ventura J, Martinez E, Sánchez S, Hernandez G, Ortega L, et al. Fn14 is upregulated in cytokine-stimulated vascular smooth muscle cells and is expressed in human carotid atherosclerotic plaques: modulation by atorvastatin. Stroke. 2006;37:2044-53 pubmed
|
Guillemot L, Citi S. Cingulin regulates claudin-2 expression and cell proliferation through the small GTPase RhoA. Mol Biol Cell. 2006;17:3569-77 pubmed
|
Rajnicek A, Foubister L, McCaig C. Temporally and spatially coordinated roles for Rho, Rac, Cdc42 and their effectors in growth cone guidance by a physiological electric field. J Cell Sci. 2006;119:1723-35 pubmed
|
Rodriguez Vita J, Ruiz Ortega M, Ruperez M, Esteban V, Sanchez Lopez E, Plaza J, et al. Endothelin-1, via ETA receptor and independently of transforming growth factor-beta, increases the connective tissue growth factor in vascular smooth muscle cells. Circ Res. 2005;97:125-34 pubmed
|
Hartmann T, Burger J, Glodek A, Fujii N, Burger M. CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells. Oncogene. 2005;24:4462-71 pubmed
|
Turner L, Nicholls S, Hall A. The activity of the plexin-A1 receptor is regulated by Rac. J Biol Chem. 2004;279:33199-205 pubmed
|
Schneider T, Fetscher C, Krege S, Michel M. Signal transduction underlying carbachol-induced contraction of human urinary bladder. J Pharmacol Exp Ther. 2004;309:1148-53 pubmed
|
Prahalad P, Calvo I, Waechter H, Matthews J, Zuk A, Matlin K. Regulation of MDCK cell-substratum adhesion by RhoA and myosin light chain kinase after ATP depletion. Am J Physiol Cell Physiol. 2004;286:C693-707 pubmed
|
Fleichman M, Schneider T, Fetscher C, Michel M. Signal transduction underlying carbachol-induced contraction of rat urinary bladder. II. Protein kinases. J Pharmacol Exp Ther. 2004;308:54-8 pubmed
|
Surks H, Richards C, Mendelsohn M. Myosin phosphatase-Rho interacting protein. A new member of the myosin phosphatase complex that directly binds RhoA. J Biol Chem. 2003;278:51484-93 pubmed
|
Wibberley A, Chen Z, Hu E, Hieble J, Westfall T. Expression and functional role of Rho-kinase in rat urinary bladder smooth muscle. Br J Pharmacol. 2003;138:757-66 pubmed
|
Altmann C, Steenpass V, Czyborra P, Hein P, Michel M. Comparison of signalling mechanisms involved in rat mesenteric microvessel contraction by noradrenaline and sphingosylphosphorylcholine. Br J Pharmacol. 2003;138:261-71 pubmed
|
Jung J, Yoon T, Choi E, Lee K. Interaction of cofilin with triose-phosphate isomerase contributes glycolytic fuel for Na,K-ATPase via Rho-mediated signaling pathway. J Biol Chem. 2002;277:48931-7 pubmed
|
Hippenstiel S, Schmeck B, N Guessan P, Seybold J, Krüll M, Preissner K, et al. Rho protein inactivation induced apoptosis of cultured human endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2002;283:L830-8 pubmed
|
An S, Laudadio R, Lai J, Rogers R, Fredberg J. Stiffness changes in cultured airway smooth muscle cells. Am J Physiol Cell Physiol. 2002;283:C792-801 pubmed
|
Huang J, Hamasaki H, Nakamoto T, Honda H, Hirai H, Saito M, et al. Differential regulation of cell migration, actin stress fiber organization, and cell transformation by functional domains of Crk-associated substrate. J Biol Chem. 2002;277:27265-72 pubmed
|
Vinson M, Strijbos P, Rowles A, Facci L, Moore S, Simmons D, et al. Myelin-associated glycoprotein interacts with ganglioside GT1b. A mechanism for neurite outgrowth inhibition. J Biol Chem. 2001;276:20280-5 pubmed
|