This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
Y-27632 dihydrochloride
目录 :
1254/10
规格 :
10毫克
价格 :
316美元
文章摘录数: 247
参考文献
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产品信息
品牌 :
Tocris
master code :
1254
SKU号 :
1254/10
产品名称 :
Y-27632 dihydrochloride
描述 :
Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component
靶标 :
Rho-kinase Inhibitors
类别 :
Small Molecules
单位尺寸 :
10毫克
纯度 :
98%
观察到的分子量 :
320.26
网址印刷 :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
Y-27632 dihydrochloride is a selective ROCK inhibitor (Ki values are 0.14-0.22, 0.3, 25, 26 and 250 M for ROCK1 (p160 ROCK), ROCK2, PKA, PKC and MLCK respectively). Also inhibits PRK2 (IC50 = 600 nM). Increases survival rate of human embryonic stem (hES) cells and iPSC undergoing cryopreservation. Used in combination with CHIR99021, RepSox, Forskolin, SP 600125, Go 6983 and VPA to reprogram fibroblasts to mature neurons. Also optimizes naive human pluripotent stem cell growth and viability following naive cell derivation from primed ESCs and iPSCs using naive human stem cell medium (NHSM). Used as component of growth media for urothelial organoids. Cell-permeable, orally bioavailable and active in vivo . . Y-27632 synthesized to cGMP guidelines also available.
catalog number base :
1254
extended description :
Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component
化学品名文本 :
trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
配方 :
C 14 H 21 N 3 O.2HCl
配方文本 :
C14H21N3O.2HCl
cas num :
129830-38-2
美元2021 :
292
美元2022 :
316美元
产品细节 :
Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component
atl names :
y27632, Y-27632 2HCl, ROCK inhibitor, ROCK1 inhibitor
储存 :
Desiccate at RT
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国