产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
SB 202190
目录 :
1264/10
规格 :
10 mg (also 50 mg)
价格 :
258美元
更多信息或购买 :
文章摘录数: 37
参考文献
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Tichet M, Prod homme V, Fenouille N, Ambrosetti D, Mallavialle A, Cerezo M, et al. Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis. Nat Commun. 2015;6:6993 pubmed 出版商
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产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
1264
SKU号 :
1264/10
产品名称 :
SB 202190
描述 :
Potent, selective inhibitor of p38 MAPK
靶标 :
p38 Inhibitors
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
99%
观察到的分子量 :
331.35
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
SB 202190 is a highly selective, potent and cell-permeable inhibitor of p38 MAP kinase. Binds within the ATP pocket of the active kinase (Kd = 38 nM, as measured in recombinant human p38), and selectively inhibits the p38 and isoforms (IC50 = 50 and 100 nM at SAPK2a/p38 and SAPK2b/p38 2 respectively). Promotes stability of naive human pluripotent stem cells in culture. Inhibits Yamanaka factor reprogramming of human fibroblasts to iPSCs. SB 202190 improves the self-renewal ability of neuronal stem cells from NPC1-deficient mice.
extended description :
Potent, selective inhibitor of p38 MAPK
化学品名文本 :
4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol
配方 :
C 20 H 14 N 3 OF
配方文本 :
C20H14N3OF
cas num :
152121-30-7
美元 :
258美元
产品细节 :
Potent, selective inhibitor of p38 MAPK
储存 :
存放在-20°C
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国