产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
CP 94253 hydrochloride
目录 :
1317/10
规格 :
10 mg (also 50 mg)
价格 :
261美元
更多信息或购买 :
Tocris Bioscience 产品网页
文章摘录数: 7
参考文献
Gadgaard C, Jensen A. Functional characterization of 5-HT1A and 5-HT1B serotonin receptor signaling through G-protein-activated inwardly rectifying K+ channels in a fluorescence-based membrane potential assay. Biochem Pharmacol. 2020;175:113870 pubmed 出版商
El Mansari M, Lecours M, Blier P. Effects of acute and sustained administration of vortioxetine on the serotonin system in the hippocampus: electrophysiological studies in the rat brain. Psychopharmacology (Berl). 2015;232:2343-52 pubmed 出版商
Doslikova B, Garfield A, Shaw J, Evans M, Burdakov D, Billups B, et al. 5-HT2C receptor agonist anorectic efficacy potentiated by 5-HT1B receptor agonist coapplication: an effect mediated via increased proportion of pro-opiomelanocortin neurons activated. J Neurosci. 2013;33:9800-4 pubmed 出版商
Eriksson T, Alvarsson A, Stan T, Zhang X, Hascup K, Hascup E, et al. Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11. Mol Psychiatry. 2013;18:1096-105 pubmed 出版商
Hagan C, McDevitt R, Liu Y, Furay A, Neumaier J. 5-HT(1B) autoreceptor regulation of serotonin transporter activity in synaptosomes. Synapse. 2012;66:1024-34 pubmed 出版商
McDevitt R, Hiroi R, MacKenzie S, Robin N, Cohn A, Kim J, et al. Serotonin 1B autoreceptors originating in the caudal dorsal raphe nucleus reduce expression of fear and depression-like behavior. Biol Psychiatry. 2011;69:780-7 pubmed 出版商
Heisler L, Jobst E, Sutton G, Zhou L, Borok E, Thornton Jones Z, et al. Serotonin reciprocally regulates melanocortin neurons to modulate food intake. Neuron. 2006;51:239-49 pubmed
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
1317
SKU号 :
1317/10
产品名称 :
CP 94253 hydrochloride
描述 :
Potent and selective 5-HT1B agonist
靶标 :
5-HT1B Receptor Agonists
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
98%
观察到的分子量 :
293.8
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
CP 94253 hydrochloride is a potent, selective 5-HT1B agonist (Ki values are 89, 2, 860, 49 and 1,600 nM for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D and 5-HT2 receptors respectively). Centrally active upon systemic administration in vivo .
extended description :
Potent and selective 5-HT1B agonist
化学品名文本 :
5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine hydrochloride
配方 :
C 15 H 19 N 3 O.氯化氢
配方文本 :
C15H19N3O.氯化氢
cas num :
845861-39-4
美元 :
261美元
产品细节 :
Potent and selective 5-HT1B agonist
储存 :
Desiccate at RT
更多信息或购买 :
Tocris Bioscience 产品网页
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国