产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
ZM 336372
目录 :
1321/10
规格 :
10 mg (also 50 mg)
价格 :
254美元
更多信息或购买 :
文章摘录数: 4
| 参考文献 |
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Alao J, Stavropoulou A, Lam E, Coombes R. Role of glycogen synthase kinase 3 beta (GSK3beta) in mediating the cytotoxic effects of the histone deacetylase inhibitor trichostatin A (TSA) in MCF-7 breast cancer cells. Mol Cancer. 2006;5:40 pubmed
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Stockand J, Meszaros J. Aldosterone stimulates proliferation of cardiac fibroblasts by activating Ki-RasA and MAPK1/2 signaling. Am J Physiol Heart Circ Physiol. 2003;284:H176-84 pubmed
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产品信息
品牌 :
Tocris
master code :
1321
SKU号 :
1321/10
产品名称 :
ZM 336372
描述 :
Potent, selective c-Raf inhibitor
靶标 :
Raf Kinase Inhibitors
类别 :
Small Molecules
sizes available :
10 mg (also 50 mg)
纯度 :
99%
观察到的分子量 :
389.45
网址印刷 :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
ZM 336372 is a potent, selective inhibitor of c-Raf in vitro (IC50 = 70 nM for inhibition of human c-Raf). Shows 10-fold selectivity over B-Raf. Also inhibits SAPK2/p38 (IC50 = 2 u M). Selective over 17 other protein kinases including PKA, PKC, p42 MAPK, CDK1 and SAPK1/JNK (up to 50 u M).
extended description :
Potent, selective c-Raf inhibitor
化学品名文本 :
3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)-amino]-4-methylphenyl]benzamide
配方 :
C 23 H 23 N 3 O 3
配方文本 :
C23H23N3O3
cas num :
208260-29-1
美元 :
241
美元2023 :
254美元
产品细节 :
Potent, selective c-Raf inhibitor
储存 :
存放在+4°C
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
公司总部: 英国