产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
PD 123319 ditrifluoroacetate
目录 :
1361/10
规格 :
10 mg (also 50 mg)
价格 :
290美元
更多信息或购买 :
文章摘录数: 22
参考文献 |
---|
Raffai G, Lombard J. Angiotensin-(1-7) Selectively Induces Relaxation and Modulates Endothelium-Dependent Dilation in Mesenteric Arteries of Salt-Fed Rats. J Vasc Res. 2016;53:105-118 pubmed
|
Fan Y, Wang L, Liu C, Zhu H, Zhou L, Wang Y, et al. Local renin-angiotensin system regulates hypoxia-induced vascular endothelial growth factor synthesis in mesenchymal stem cells. Int J Clin Exp Pathol. 2015;8:2505-14 pubmed
|
Porter A, Pillidge K, Grabowska E, Stanford S. The angiotensin converting enzyme inhibitor, captopril, prevents the hyperactivity and impulsivity of neurokinin-1 receptor gene 'knockout' mice: sex differences and implications for the treatment of attention deficit hyperactivity disorder. Eur Neuropsychopharmacol. 2015;25:512-21 pubmed 出版商
|
Speth R, Vento P, Carrera E, Gonzalez Reily L, Linares A, Santos K, et al. Acute repeated intracerebroventricular injections of angiotensin II reduce agonist and antagonist radioligand binding in the paraventricular nucleus of the hypothalamus and median preoptic nucleus in the rat brain. Brain Res. 2014;1583:132-40 pubmed 出版商
|
Benkirane K, Amiri F, Diep Q, El Mabrouk M, Schiffrin E. PPAR-gamma inhibits ANG II-induced cell growth via SHIP2 and 4E-BP1. Am J Physiol Heart Circ Physiol. 2006;290:H390-7 pubmed
|
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
1361
SKU号 :
1361/10
产品名称 :
PD 123319 ditrifluoroacetate
描述 :
Potent and selective non-peptide AT2 antagonist
靶标 :
Angiotensin AT2 Receptor Antagonists
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
99%
观察到的分子量 :
736.67
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist. IC50 values are 34 and 210 nM in rat adrenal tissue and brain respectively.
extended description :
Potent and selective non-peptide AT2 antagonist
化学品名文本 :
(6S)1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid ditrifluoroacetate
配方 :
C 31 H 32 N 4 O 3。 2CF 3 CO 2 H
配方文本 :
C31H32N4O3.2CF3CO2H
cas num :
136676-91-0
美元 :
290美元
产品细节 :
Potent and selective non-peptide AT2 antagonist
储存 :
存放在-20°C
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
公司总部: 英国