产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
SB 203580 hydrochloride
目录 :
1402/10
规格 :
10毫克
价格 :
377美元
更多信息或购买 :
文章摘录数: 11
参考文献
Li R, Zhong C, Yu Y, Liu H, Sakurai M, Yu L, et al. Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures. Cell. 2019;179:687-702.e18 pubmed 出版商
Zhang W, Du L, Zheng X, Chen X, Shi C, Chen B, et al. Elevated sodium chloride drives type I interferon signaling in macrophages and increases antiviral resistance. J Biol Chem. 2018;293:1030-1039 pubmed 出版商
Yang J, Ryan D, Wang W, Tsang J, Lan G, Masaki H, et al. Establishment of mouse expanded potential stem cells. Nature. 2017;550:393-397 pubmed 出版商
Silpanisong J, Kim D, Williams J, Adeoye O, Thorpe R, Pearce W. Chronic hypoxia alters fetal cerebrovascular responses to endothelin-1. Am J Physiol Cell Physiol. 2017;313:C207-C218 pubmed 出版商
Lukjanenko L, Jung M, Hegde N, Perruisseau Carrier C, Migliavacca E, Rozo M, et al. Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice. Nat Med. 2016;22:897-905 pubmed 出版商
Eden D, Siegbahn A, Mokhtari D. Tissue factor/factor VIIa signalling promotes cytokine-induced beta cell death and impairs glucose-stimulated insulin secretion from human pancreatic islets. Diabetologia. 2015;58:2563-72 pubmed 出版商
Mans R, Warmus B, Smith C, McMahon L. An acetylcholinesterase inhibitor, eserine, induces long-term depression at CA3-CA1 synapses in the hippocampus of adult rats. J Neurophysiol. 2014;112:2388-97 pubmed 出版商
Nguyen T, Kwon S, Hong S, Ma S, Jung Y, Hwang J, et al. Transient receptor potential vanilloid type 1 channel may modulate opioid reward. Neuropsychopharmacology. 2014;39:2414-22 pubmed 出版商
Williams K, Ghosh R, Giridhar P, Gu G, Case T, Belcher S, et al. Inhibition of stathmin1 accelerates the metastatic process. Cancer Res. 2012;72:5407-17 pubmed 出版商
Engel F, Hsieh P, Lee R, Keating M. FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction. Proc Natl Acad Sci U S A. 2006;103:15546-51 pubmed
Schlemper V, Medeiros R, Ferreira J, Campos M, Calixto J. Mechanisms underlying the relaxation response induced by bradykinin in the epithelium-intact guinea-pig trachea in vitro. Br J Pharmacol. 2005;145:740-50 pubmed
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
1402
SKU号 :
1402/10
产品名称 :
SB 203580 hydrochloride
描述 :
Selective inhibitor of p38 MAPK; water-soluble
靶标 :
p38 Inhibitors
类别 :
Small Molecules
单位尺寸 :
10毫克
纯度 :
98%
观察到的分子量 :
413.89
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
SB 203580 hydrochloride is a water-soluble salt of SB 203580 (Cat. No. 1202). Selective inhibitor of p38 mitogen-activated protein kinase (IC50 values are 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38 2 respectively). Displays 100-500-fold selectivity over LCK, GSK3 and PKB . Shown to inhibit interleukin-2-induced T cell proliferation, cyclooxygenase-1 and -2, and thromboxane synthase.
extended description :
Selective inhibitor of p38 MAPK; water-soluble
化学品名文本 :
4-[5-(4-Fluorophenyl)-2-[4-(methylsulphonyl)phenyl]-1H-imidazol-4-yl]pyridine hydrochloride
配方 :
C 21 H 16 FN 3 OS.氯化氢
配方文本 :
C21H16FN3OS.氯化氢
cas num :
869185-85-3
美元 :
377美元
产品细节 :
Selective inhibitor of p38 MAPK; water-soluble
储存 :
存放在-20°C
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国