产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
DCEBIO
目录 :
1422/10
规格 :
10 mg (also 50 mg)
价格 :
152美元
更多信息或购买 :
文章摘录数: 5
参考文献
McCully M, Collins P, Hughes T, Thomas C, Billen J, O Donnell V, et al. Skin Metabolites Define a New Paradigm in the Localization of Skin Tropic Memory T Cells. J Immunol. 2015;195:96-104 pubmed 出版商
Laube M, Kimpel S, Dietl P, Thome U, Wittekindt O. Benzimidazolones enhance the function of epithelial Na? transport. Br J Pharmacol. 2013;168:1329-40 pubmed 出版商
Hirota C, McKay D. Loss of Ca-mediated ion transport during colitis correlates with reduced ion transport responses to a Ca-activated K channel opener. Br J Pharmacol. 2009;156:1085-97 pubmed 出版商
MacVinish L, Cope G, Ropenga A, Cuthbert A. Chloride transporting capability of Calu-3 epithelia following persistent knockdown of the cystic fibrosis transmembrane conductance regulator, CFTR. Br J Pharmacol. 2007;150:1055-65 pubmed
Fioretti B, Pietrangelo T, Catacuzzeno L, Franciolini F. Intermediate-conductance Ca2+-activated K+ channel is expressed in C2C12 myoblasts and is downregulated during myogenesis. Am J Physiol Cell Physiol. 2005;289:C89-96 pubmed
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
1422
SKU号 :
1422/10
产品名称 :
DCEBIO
描述 :
Activates Cl- conductance and hKCa3.1 channels
靶标 :
CFTR Activators
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
99%
观察到的分子量 :
231.08
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
DCEBIO is a stimulates Cl- secretion via the activation of hKCa3.1 (IK1) potassium channels and an apical Cl- conductance carried by the CFTR channel. More potent than its analog 1-EBIO (Cat. No. 1041).
extended description :
Activates Cl- conductance and hKCa3.1 channels
化学品名文本 :
5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one
配方 :
C 9 H 8 Cl 2 N 2 O
配方文本 :
C9H8Cl2N2O
cas num :
60563-36-2
美元 :
152美元
产品细节 :
Activates Cl- conductance and hKCa3.1 channels
储存 :
存放在RT
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国