产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
Citalopram hydrobromide
目录 :
1427/10
规格 :
10 mg (also 50 mg)
价格 :
183美元
更多信息或购买 :
文章摘录数: 14
参考文献
Matsui A, Alvarez V. Cocaine Inhibition of Synaptic Transmission in the Ventral Pallidum Is Pathway-Specific and Mediated by Serotonin. Cell Rep. 2018;23:3852-3863 pubmed 出版商
Gasull Camós J, Martínez Torres S, Tarrés Gatius M, Ozaita A, Artigas F, Castañé A. Serotonergic mechanisms involved in antidepressant-like responses evoked by GLT-1 blockade in rat infralimbic cortex. Neuropharmacology. 2018;139:41-51 pubmed 出版商
Munari L, Provensi G, Passani M, Galeotti N, Cassano T, Benetti F, et al. Brain Histamine Is Crucial for Selective Serotonin Reuptake Inhibitors' Behavioral and Neurochemical Effects. Int J Neuropsychopharmacol. 2015;18:pyv045 pubmed 出版商
Phelps C, Mitchell E, Nutt D, Marston H, Robinson E. Psychopharmacological characterisation of the successive negative contrast effect in rats. Psychopharmacology (Berl). 2015;232:2697-709 pubmed 出版商
Jury N, McCormick B, Horseman N, Benoit S, Gregerson K. Enhanced responsiveness to selective serotonin reuptake inhibitors during lactation. PLoS ONE. 2015;10:e0117339 pubmed 出版商
Nolan T, Geffert L, Kolber B, Madura J, Surratt C. Discovery of novel-scaffold monoamine transporter ligands via in silico screening with the S1 pocket of the serotonin transporter. ACS Chem Neurosci. 2014;5:784-92 pubmed 出版商
Jiménez Sánchez L, Campa L, Auberson Y, Adell A. The role of GluN2A and GluN2B subunits on the effects of NMDA receptor antagonists in modeling schizophrenia and treating refractory depression. Neuropsychopharmacology. 2014;39:2673-80 pubmed 出版商
Stuart S, Butler P, Munafò M, Nutt D, Robinson E. A translational rodent assay of affective biases in depression and antidepressant therapy. Neuropsychopharmacology. 2013;38:1625-35 pubmed 出版商
Morecroft I, White K, Caruso P, Nilsen M, Loughlin L, Alba R, et al. Gene therapy by targeted adenovirus-mediated knockdown of pulmonary endothelial Tph1 attenuates hypoxia-induced pulmonary hypertension. Mol Ther. 2012;20:1516-28 pubmed 出版商
Hutchinson A, Deng J, Aryal D, Wetsel W, West A. Differential regulation of MeCP2 phosphorylation in the CNS by dopamine and serotonin. Neuropsychopharmacology. 2012;37:321-37 pubmed 出版商
Murray K, Nakae A, Stephens M, Rank M, D Amico J, Harvey P, et al. Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors. Nat Med. 2010;16:694-700 pubmed 出版商
Morecroft I, Pang L, Baranowska M, Nilsen M, Loughlin L, Dempsie Y, et al. In vivo effects of a combined 5-HT1B receptor/SERT antagonist in experimental pulmonary hypertension. Cardiovasc Res. 2010;85:593-603 pubmed 出版商
Maciag D, Coppinger D, Paul I. Evidence that the deficit in sexual behavior in adult rats neonatally exposed to citalopram is a consequence of 5-HT1 receptor stimulation during development. Brain Res. 2006;1125:171-5 pubmed
Maciag D, Simpson K, Coppinger D, Lu Y, Wang Y, Lin R, et al. Neonatal antidepressant exposure has lasting effects on behavior and serotonin circuitry. Neuropsychopharmacology. 2006;31:47-57 pubmed
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
1427
SKU号 :
1427/10
产品名称 :
Citalopram hydrobromide
描述 :
Highly potent and selective 5-HT uptake inhibitor
靶标 :
5-HT Transporter Inhibitors
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
99%
观察到的分子量 :
405.31
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
Citalopram hydrobromide is a highly selective and potent 5-HT uptake inhibitor with no effect on noradrenalin or dopamine uptake (IC50 values are 1.8, 8800 and 41000 nM respectively). Has negligible activity at a wide range of receptors.
extended description :
Highly potent and selective 5-HT uptake inhibitor
化学品名文本 :
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile hydrobromide
配方 :
C 20 H 21 FN 2 O.HBr
配方文本 :
C20H21FN2O.HBr
cas num :
59729-32-7
美元 :
183美元
产品细节 :
Highly potent and selective 5-HT uptake inhibitor
储存 :
存放在RT
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国