产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
BQ 788钠盐
目录 :
1500/1
规格 :
1毫克
价格 :
437美元
更多信息或购买 :
文章摘录数: 8
参考文献
Durgan D, Crossland R, Lloyd E, Phillips S, Bryan R. Increased cerebrovascular sensitivity to endothelin-1 in a rat model of obstructive sleep apnea: a role for endothelin receptor B. J Cereb Blood Flow Metab. 2015;35:402-11 pubmed 出版商
Patel C, Narayanan S, Zhang W, Xu Z, Sukumari Ramesh S, Dhandapani K, et al. Activation of the endothelin system mediates pathological angiogenesis during ischemic retinopathy. Am J Pathol. 2014;184:3040-51 pubmed 出版商
Sanchez A, Martinez P, Munoz M, Benedito S, Garcia Sacristan A, Hernandez M, et al. Endothelin-1 contributes to endothelial dysfunction and enhanced vasoconstriction through augmented superoxide production in penile arteries from insulin-resistant obese rats: role of ET(A) and ET(B) receptors. Br J Pharmacol. 2014;171:5682-95 pubmed 出版商
Ou M, Dang Y, Mazzuca M, Basile R, Khalil R. Adaptive regulation of endothelin receptor type-A and type-B in vascular smooth muscle cells during pregnancy in rats. J Cell Physiol. 2014;229:489-501 pubmed 出版商
Allahdadi K, Hannan J, Tostes R, Webb R. Endothelin-1 induces contraction of female rat internal pudendal and clitoral arteries through ET(A) receptor and rho-kinase activation. J Sex Med. 2010;7:2096-2103 pubmed 出版商
Yeligar S, Tsukamoto H, Kalra V. Ethanol-induced expression of ET-1 and ET-BR in liver sinusoidal endothelial cells and human endothelial cells involves hypoxia-inducible factor-1alpha and microrNA-199. J Immunol. 2009;183:5232-43 pubmed 出版商
Sutcliffe A, Clarke D, Bradbury D, Corbett L, Patel J, Knox A. Transcriptional regulation of monocyte chemotactic protein-1 release by endothelin-1 in human airway smooth muscle cells involves NF-kappaB and AP-1. Br J Pharmacol. 2009;157:436-50 pubmed 出版商
McQueen D, Noble M, Bond S. Endothelin-1 activates ETA receptors to cause reflex scratching in BALB/c mice. Br J Pharmacol. 2007;151:278-84 pubmed
产品信息
品牌 :
Tocris
MasterCode :
1500
SKU号 :
1500/1
产品名称 :
BQ 788钠盐
靶标 :
Endothelin ETB Receptor Antagonists
类别 :
Small Molecules
单位尺寸 :
1毫克
纯度 :
95%
观察到的分子量 :
663.79
网址印刷 :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
BQ 788 sodium salt is a potent, selective ETB receptor antagonist (IC50 = 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells).
extended description :
Selective ETB antagonist
化学品名文本 :
N-[(cis-2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucine sodium salt
配方 :
C 34 H 50 N 5 NaO 7
配方文本 :
C34H50N5NaO7
cas num :
156161-89-6
美元 :
437美元
产品细节 :
Selective ETB antagonist
储存 :
Desiccate at -20°C
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国