产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
Baicalein
目录 :
1761/50
规格 :
50毫克
价格 :
122美元
更多信息或购买 :
Tocris Bioscience 产品网页
文章摘录数: 6
参考文献
Oguh Olayinka L, Agarwal V, Ranatunge D, Campbell A, Laufer S, Cawkwell L, et al. The Investigation of Lipoxygenases as Therapeutic Targets in Malignant Pleural Mesothelioma. Pathol Oncol Res. 2019;: pubmed 出版商
Mishra B, Lovewell R, Olive A, Zhang G, Wang W, Eugenin E, et al. Nitric oxide prevents a pathogen-permissive granulocytic inflammation during tuberculosis. Nat Microbiol. 2017;2:17072 pubmed 出版商
Maskrey B, Rushworth G, Law M, Treweeke A, Wei J, Leslie S, et al. 12-hydroxyeicosatetraenoic acid is associated with variability in aspirin-induced platelet inhibition. J Inflamm (Lond). 2014;11:33 pubmed 出版商
Potapova I, Cohen I, Doronin S. Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. PLoS ONE. 2013;8:e73929 pubmed 出版商
Starowicz K, Makuch W, Korostynski M, Malek N, Slezak M, Zychowska M, et al. Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism. PLoS ONE. 2013;8:e60040 pubmed 出版商
Gibson H, Edwards J, Page R, Van Hook M, Kauer J. TRPV1 channels mediate long-term depression at synapses on hippocampal interneurons. Neuron. 2008;57:746-59 pubmed 出版商
产品信息
品牌 :
Tocris
master code :
1761
SKU号 :
1761/50
产品名称 :
Baicalein
描述 :
5-和12脂肪氧化酶抑制剂
靶标 :
脂肪氧化酶抑制剂
类别 :
Small Molecules
单位尺寸 :
50毫克
纯度 :
98%
观察到的分子量 :
270.24
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
Baicalein is an inhibitor of 5- and platelet 12-lipoxygenases (IC50 values are 9.5 and 0.12 M respectively). Also inhibits Raf-mediated MEK-1 phosphorylation in C6 rat glioma cells and induces G1 and G2 cell cycle arrest by decreasing cdk1, cdk2, cyclin D2 and cyclin A expression. Inhibits production of inflammatory cytokines by inhibiting NF- B activation. Also inhibits erastin-induced ferroptosis.
extended description :
5-和12脂肪氧化酶抑制剂
化学品名文本 :
5,6,7-Trihydroxy-2-phenyl-(4H)-1-benzopyran-4-one
配方 :
C 15 H 10 O 5
配方文本 :
C15H10O5
cas num :
491-67-8
美元 :
122美元
产品细节 :
5-和12脂肪氧化酶抑制剂
储存 :
Desiccate at -20°C
更多信息或购买 :
Tocris Bioscience 产品网页
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国