产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
MPP dihydrochloride
目录 :
1991
规格 :
10 mg (also 50 mg)
价格 :
186美元
更多信息或购买 :
文章摘录数: 28
参考文献
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Al Khyatt W, Tufarelli C, Khan R, Iftikhar S. Selective oestrogen receptor antagonists inhibit oesophageal cancer cell proliferation in vitro. BMC Cancer. 2018;18:121 pubmed 出版商
Fátima L, Campello R, Santos R, Freitas H, Frank A, Machado U, et al. Estrogen receptor 1 (ESR1) regulates VEGFA in adipose tissue. Sci Rep. 2017;7:16716 pubmed 出版商
Luo F, Huang W, Guo Y, Ruan G, Peng R, Li X. 17?-estradiol lowers triglycerides in adipocytes via estrogen receptor ? and it may be attenuated by inflammation. Lipids Health Dis. 2017;16:182 pubmed 出版商
Villar Pazos S, Martinez Pinna J, Castellano Muñoz M, Alonso Magdalena P, Marroquí L, Quesada I, et al. Molecular mechanisms involved in the non-monotonic effect of bisphenol-a on ca2+ entry in mouse pancreatic β-cells. Sci Rep. 2017;7:11770 pubmed 出版商
Lou Y, Hu M, Wang Q, Yuan M, Wang N, Le F, et al. Estradiol Suppresses TLR4-triggered Apoptosis of Decidual Stromal Cells and Drives an Anti-inflammatory TH2 Shift by Activating SGK1. Int J Biol Sci. 2017;13:434-448 pubmed 出版商
Caballero I, Boyd J, Almiñana C, Sánchez López J, Basatvat S, Montazeri M, et al. Understanding the dynamics of Toll-like Receptor 5 response to flagellin and its regulation by estradiol. Sci Rep. 2017;7:40981 pubmed 出版商
Wójtowicz A, Szychowski K, Wnuk A, Kajta M. Dibutyl Phthalate (DBP)-Induced Apoptosis and Neurotoxicity are Mediated via the Aryl Hydrocarbon Receptor (AhR) but not by Estrogen Receptor Alpha (ERα), Estrogen Receptor Beta (ERβ), or Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) in Mo. Neurotox Res. 2017;31:77-89 pubmed 出版商
Pastore M, Talwar S, Conley M, Magness R. Identification of Differential ER-Alpha Versus ER-Beta Mediated Activation of eNOS in Ovine Uterine Artery Endothelial Cells. Biol Reprod. 2016;94:139 pubmed 出版商
Xing L, Esau C, Trudeau V. Direct Regulation of Aromatase B Expression by 17β-Estradiol and Dopamine D1 Receptor Agonist in Adult Radial Glial Cells. Front Neurosci. 2015;9:504 pubmed 出版商
Bertrand S, Hu C, Aksenova M, Mactutus C, Booze R. HIV-1 Tat and cocaine mediated synaptopathy in cortical and midbrain neurons is prevented by the isoflavone Equol. Front Microbiol. 2015;6:894 pubmed 出版商
Wang L, Qiu X, Gui Y, Xu Y, Gober H, Li D. Bu-Shen-Ning-Xin decoction: inhibition of osteoclastogenesis by abrogation of the RANKL-induced NFATc1 and NF-κB signaling pathways via selective estrogen receptor α. Drug Des Devel Ther. 2015;9:3755-66 pubmed 出版商
Gao X, Ma J, Chen Y, Wang H. Rapid responses and mechanism of action for low-dose bisphenol S on ex vivo rat hearts and isolated myocytes: evidence of female-specific proarrhythmic effects. Environ Health Perspect. 2015;123:571-8 pubmed 出版商
Mazzuca M, Mata K, Li W, Rangan S, Khalil R. Estrogen receptor subtypes mediate distinct microvascular dilation and reduction in [Ca2+]I in mesenteric microvessels of female rat. J Pharmacol Exp Ther. 2015;352:291-304 pubmed 出版商
Koong L, Watson C. Direct estradiol and diethylstilbestrol actions on early- versus late-stage prostate cancer cells. Prostate. 2014;74:1589-603 pubmed 出版商
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Giordano G, Tait L, Furlong C, Cole T, Kavanagh T, Costa L. Gender differences in brain susceptibility to oxidative stress are mediated by levels of paraoxonase-2 expression. Free Radic Biol Med. 2013;58:98-108 pubmed 出版商
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产品信息
品牌 :
Tocris
master code :
1991
SKU号 :
1991/10
产品名称 :
MPP dihydrochloride
描述 :
Highly selective ER antagonist
靶标 :
Estrogen and Related Receptor Antagonists
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
98%
观察到的分子量 :
542.5
网址印刷 :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
Selective, high affinity silent antagonist at ER receptors. Displays 200-fold selectivity for ER over ER . Ki values are 2.7 and 1800 nM at ER and ER receptors respectively.
catalog number base :
1991
产品关键词 :
selective Erα receptor antagonist; ERalpha antagonists ER ERR Estrogen Receptors Estrogen and Related Receptors 1991,
extended description :
Highly selective ER antagonist
化学品名文本 :
1,3-Bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidinylethoxy)phenol]-1H-pyrazole dihydrochloride
配方 :
C 29 H 31 N 3 O 3。 2HCl
配方文本 :
C29H31N3O3.2HCl
cas num :
911295-24-4
2020美元 :
178
2021美元 :
186美元
储存 :
存放在+4°C
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国