产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
顺铂
目录 :
2251/50
规格 :
50毫克
价格 :
121美元
更多信息或购买 :
文章摘录数: 25
参考文献
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Brown J, Yonekubo Y, Hanson N, Sastre Perona A, Basin A, Rytlewski J, et al. TGF-β-Induced Quiescence Mediates Chemoresistance of Tumor-Propagating Cells in Squamous Cell Carcinoma. Cell Stem Cell. 2017;21:650-664.e8 pubmed 出版商
Chia S, Low J, Zhang X, Kwang X, Chong F, Sharma A, et al. Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time. Nat Commun. 2017;8:435 pubmed 出版商
Zhang H, Patel A, Wang Y, Zhang Y, Kathawala R, Qiu L, et al. The BTK Inhibitor Ibrutinib (PCI-32765) Overcomes Paclitaxel Resistance in ABCB1- and ABCC10-Overexpressing Cells and Tumors. Mol Cancer Ther. 2017;16:1021-1030 pubmed 出版商
Florea A, Varghese E, McCallum J, Mahgoub S, Helmy I, Varghese S, et al. Calcium-regulatory proteins as modulators of chemotherapy in human neuroblastoma. Oncotarget. 2017;8:22876-22893 pubmed 出版商
Deng L, Ng L, Ozawa T, Stella N. Quantitative Analyses of Synergistic Responses between Cannabidiol and DNA-Damaging Agents on the Proliferation and Viability of Glioblastoma and Neural Progenitor Cells in Culture. J Pharmacol Exp Ther. 2017;360:215-224 pubmed 出版商
Fedoseienko A, Wieringa H, Wisman G, Duiker E, Reyners A, Hofker M, et al. Nuclear COMMD1 Is Associated with Cisplatin Sensitivity in Ovarian Cancer. PLoS ONE. 2016;11:e0165385 pubmed 出版商
Kim M, Caplen N, Chakka S, Hernandez L, House C, Pongas G, et al. Identification of therapeutic targets applicable to clinical strategies in ovarian cancer. BMC Cancer. 2016;16:678 pubmed 出版商
Sun R, Jiang B, Qi H, Zhang X, Yang J, Duan J, et al. SOX4 contributes to the progression of cervical cancer and the resistance to the chemotherapeutic drug through ABCG2. Cell Death Dis. 2015;6:e1990 pubmed 出版商
Lin H, Heo B, Yoon M. A New Rat Model of Cisplatin-induced Neuropathic Pain. Korean J Pain. 2015;28:236-43 pubmed 出版商
Saja M, Baudino L, Jackson W, Cook H, Malik T, Fossati Jimack L, et al. Triglyceride-Rich Lipoproteins Modulate the Distribution and Extravasation of Ly6C/Gr1(low) Monocytes. Cell Rep. 2015;12:1802-15 pubmed 出版商
Marcus D, Zee M, Hughes A, Yuill M, Hohmann A, Mackie K, et al. Tolerance to the antinociceptive effects of chronic morphine requires c-Jun N-terminal kinase. Mol Pain. 2015;11:34 pubmed 出版商
Kathawala R, Wei L, Anreddy N, Chen K, Patel A, Alqahtani S, et al. The small molecule tyrosine kinase inhibitor NVP-BHG712 antagonizes ABCC10-mediated paclitaxel resistance: a preclinical and pharmacokinetic study. Oncotarget. 2015;6:510-21 pubmed
Liu Y, Kwiatkowski D. Combined CDKN1A/TP53 mutation in bladder cancer is a therapeutic target. Mol Cancer Ther. 2015;14:174-82 pubmed 出版商
Guindon J, Deng L, Fan B, Wager Miller J, Hohmann A. Optimization of a cisplatin model of chemotherapy-induced peripheral neuropathy in mice: use of vitamin C and sodium bicarbonate pretreatments to reduce nephrotoxicity and improve animal health status. Mol Pain. 2014;10:56 pubmed 出版商
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产品信息
品牌 :
Tocris
MasterCode :
2251
SKU号 :
2251/50
产品名称 :
顺铂
靶标 :
Caspase Activators
类别 :
Small Molecules
单位尺寸 :
50毫克
观察到的分子量 :
300.05
网址印刷 :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
Cisplatin is a potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent mechanisms. Inhibits X-linked inhibitor of apoptosis protein (XIAP) expression and activates caspase-3. In certain glioma cell lines, sensitizes cells to TNF- -induced apoptosis.
extended description :
Potent pro-apoptotic anticancer agent; activates caspase-3
化学品名文本 :
cis-Diaminodichloroplatinum
配方 :
Cl 2 H 6 N 2 Pt
配方文本 :
Cl2H6N2Pt
cas num :
15663-27-1
美元 :
121美元
产品细节 :
Potent pro-apoptotic anticancer agent; activates caspase-3
别名 :
CDDP
储存 :
存放在RT
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国