产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
SR 11302
目录 :
2476/10
规格 :
10毫克
价格 :
290美元
更多信息或购买 :
文章摘录数: 26
参考文献
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Messerschmidt L, Fischer S, Wiedemann P, Bringmann A, Hollborn M. Osmotic induction of cyclooxygenase-2 in RPE cells: Stimulation of inflammasome activation. Mol Vis. 2019;25:329-344 pubmed
Martin Gallausiaux C, Larraufie P, Jarry A, Béguet Crespel F, Marinelli L, Ledue F, et al. Butyrate Produced by Commensal Bacteria Down-Regulates Indolamine 2,3-Dioxygenase 1 (IDO-1) Expression via a Dual Mechanism in Human Intestinal Epithelial Cells. Front Immunol. 2018;9:2838 pubmed 出版商
Kim C, Hu B, Jadhav R, Jin J, Zhang H, Cavanagh M, et al. Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells. Cell Rep. 2018;25:2148-2162.e5 pubmed 出版商
Kleiner J, Hollborn M, Wiedemann P, Bringmann A. Activator protein-1 contributes to the NaCl-induced expression of VEGF and PlGF in RPE cells. Mol Vis. 2018;24:647-666 pubmed
Han S, Ding S, Miao X, Lin Z, Lu G, Xiao W, et al. TGF-β1 expression in regulatory NK1.1-CD4+NKG2D+ T cells dependents on the PI3K-p85α/JNK, NF-κB and STAT3 pathways. Am J Cancer Res. 2018;8:489-501 pubmed
Zhang W, Du L, Zheng X, Chen X, Shi C, Chen B, et al. Elevated sodium chloride drives type I interferon signaling in macrophages and increases antiviral resistance. J Biol Chem. 2018;293:1030-1039 pubmed 出版商
Sun Y, Lin Z, Liu C, Gong Y, Liegl R, Fredrick T, et al. Inflammatory signals from photoreceptor modulate pathological retinal angiogenesis via c-Fos. J Exp Med. 2017;214:1753-1767 pubmed 出版商
Lee F, Hui C, Chang T, Chiou P. Alternative Splicing of Toll-Like Receptor 9 Transcript in Teleost Fish Grouper Is Regulated by NF-?B Signaling via Phosphorylation of the C-Terminal Domain of the RPB1 Subunit of RNA Polymerase II. PLoS ONE. 2016;11:e0163415 pubmed 出版商
Bugel S, Wehmas L, La Du J, Tanguay R. Phenotype anchoring in zebrafish reveals a potential role for matrix metalloproteinases (MMPs) in tamoxifen's effects on skin epithelium. Toxicol Appl Pharmacol. 2016;296:31-41 pubmed 出版商
Zheng X, Cheng M, Xiang L, Liang J, Xie L, Zhang R. The AP-1 transcription factor homolog Pf-AP-1 activates transcription of multiple biomineral proteins and potentially participates in Pinctada fucata biomineralization. Sci Rep. 2015;5:14408 pubmed 出版商
Nadeau Vallée M, Quiniou C, Palacios J, Hou X, Erfani A, Madaan A, et al. Novel Noncompetitive IL-1 Receptor-Biased Ligand Prevents Infection- and Inflammation-Induced Preterm Birth. J Immunol. 2015;195:3402-15 pubmed 出版商
Banskota S, Regmi S, Kim J. NOX1 to NOX2 switch deactivates AMPK and induces invasive phenotype in colon cancer cells through overexpression of MMP-7. Mol Cancer. 2015;14:123 pubmed 出版商
Chen Q, Chen P, Pang X, Hu Y, Zhang Y. Adrenomedullin Up-regulates the Expression of Vascular Endothelial Growth Factor in Epithelial Ovarian Carcinoma Cells via JNK/AP-1 Pathway. Int J Gynecol Cancer. 2015;25:953-60 pubmed 出版商
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Huang Z, Huang G, Li Q, Jin J. p38 mitogen-activated protein kinase/activator protein-1 involved in serum deprivation-induced human alkaline ceramidase 2 upregulation. Biomed Rep. 2015;3:225-229 pubmed
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O Sullivan M, Hirota N, Martin J. Sphingosine 1-phosphate (S1P) induced interleukin-8 (IL-8) release is mediated by S1P receptor 2 and nuclear factor ?B in BEAS-2B cells. PLoS ONE. 2014;9:e95566 pubmed 出版商
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产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
2476
SKU号 :
2476/10
产品名称 :
SR 11302
描述 :
AP-1 inhibitor; antitumor agent
靶标 :
AP-1 Inhibitors
类别 :
Small Molecules
单位尺寸 :
10毫克
纯度 :
98%
观察到的分子量 :
376.54
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
SR 11302 is an inhibitor of activator protein-1 (AP-1) transcription factor activity that displays antitumor effects in vivo . Does not activate transcription from the retinoic acid response element (RARE) and displays no activity at retinoic acid receptors (EC50 1 u M for RAR , RAR , RAR and RXR ).
extended description :
AP-1 inhibitor; antitumor agent
化学品名文本 :
(E,E,Z,E)-3-Methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
配方 :
C 26 H 32 O 2
配方文本 :
C26H32O2
cas num :
160162-42-5
美元 :
290美元
产品细节 :
AP-1 inhibitor; antitumor agent
储存 :
存放在-20°C
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国