产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
Jasplakinolide
目录 :
2792/100U
规格 :
100微克
价格 :
439美元
更多信息或购买 :
Tocris Bioscience 产品网页
文章摘录数: 10
参考文献
Pfitzer L, Moser C, Gegenfurtner F, Arner A, Foerster F, Atzberger C, et al. Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy. Cell Death Dis. 2019;10:302 pubmed 出版商
Warchal S, Dawson J, Carragher N. Evaluation of Machine Learning Classifiers to Predict Compound Mechanism of Action When Transferred across Distinct Cell Lines. SLAS Discov. 2019;24:224-233 pubmed 出版商
Zhu B, Rippe C, Holmberg J, Zeng S, Perisic L, Albinsson S, et al. Nexilin/NEXN controls actin polymerization in smooth muscle and is regulated by myocardin family coactivators and YAP. Sci Rep. 2018;8:13025 pubmed 出版商
Neumann N, Perrone M, Veldhuis J, Huebner R, Zhan H, Devreotes P, et al. Coordination of Receptor Tyrosine Kinase Signaling and Interfacial Tension Dynamics Drives Radial Intercalation and Tube Elongation. Dev Cell. 2018;45:67-82.e6 pubmed 出版商
Mordue K, Hawley B, Satchwell T, Toye A. CD47 surface stability is sensitive to actin disruption prior to inclusion within the band 3 macrocomplex. Sci Rep. 2017;7:2246 pubmed 出版商
Galvez B, Gross N, Sumikawa K. Activation of α7 nicotinic acetylcholine receptors protects potentiated synapses from depotentiation during theta pattern stimulation in the hippocampal CA1 region of rats. Neuropharmacology. 2016;105:378-387 pubmed 出版商
LeClaire L, Fortwendel J. Differential Support of Aspergillus fumigatus Morphogenesis by Yeast and Human Actins. PLoS ONE. 2015;10:e0142535 pubmed 出版商
Krawczyk K, Yao Mattisson I, Ekman M, Oskolkov N, Grantinge R, Kotowska D, et al. Myocardin Family Members Drive Formation of Caveolae. PLoS ONE. 2015;10:e0133931 pubmed 出版商
TurczyÅ„ska K, Swärd K, Hien T, Wohlfahrt J, Mattisson I, Ekman M, et al. Regulation of smooth muscle dystrophin and synaptopodin 2 expression by actin polymerization and vascular injury. Arterioscler Thromb Vasc Biol. 2015;35:1489-97 pubmed 出版商
Ruprecht V, Wieser S, Callan Jones A, Smutny M, Morita H, Sako K, et al. Cortical contractility triggers a stochastic switch to fast amoeboid cell motility. Cell. 2015;160:673-685 pubmed 出版商
产品信息
品牌 :
Tocris
master code :
2792
SKU号 :
2792/100U
产品名称 :
Jasplakinolide
描述 :
Stabilizes F-actin; promotes actin polymerization
靶标 :
肌动蛋白相关产品
类别 :
Small Molecules
单位尺寸 :
100微克
纯度 :
97%
观察到的分子量 :
709.67
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
Jasplakinolide rapidly stabilizes pre-formed actin filaments and inhibits their disassembly in vitro . Also induces polymerization of actin monomers into F-actin in vivo . Shown to bind to F-actin competitively with phalloidin (Cat. No. 4535) (Kd ~ 15 nM). Exhibits antifungal and antiproliferative effects (IC50 = 35 nM for antiproliferative activity in PC3 cells). Cell permeable.
extended description :
Stabilizes F-actin; promotes actin polymerization
化学品名文本 :
Cyclo[(3R)-3-(4-hydroxyphenyl)- -alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl]
配方 :
C 36 H 45 BrN 4 O 6
配方文本 :
C36H45BrN4O6
cas num :
102396-24-7
美元 :
439美元
产品细节 :
Stabilizes F-actin; promotes actin polymerization
储存 :
存放在-20°C
更多信息或购买 :
Tocris Bioscience 产品网页
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国