产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
GM 6001
目录 :
2983/10
规格 :
10毫克
价格 :
376美元
更多信息或购买 :
Tocris Bioscience 产品网页
文章摘录数: 10
参考文献
Kim H, Yin W, Jin Y, Panza P, Gunawan F, Grohmann B, et al. Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease. Nat Commun. 2018;9:4600 pubmed 出版商
Luo F, Tran A, Xin L, Sanapala C, Lang B, Silver J, et al. Modulation of proteoglycan receptor PTPσ enhances MMP-2 activity to promote recovery from multiple sclerosis. Nat Commun. 2018;9:4126 pubmed 出版商
Lahey K, Ronaghan N, Shang J, Dion S, Desilets A, Leduc R, et al. Signaling pathways induced by serine proteases to increase intestinal epithelial barrier function. PLoS ONE. 2017;12:e0180259 pubmed 出版商
Sun C, Feng S, Cao Z, Bei J, Chen Q, Zhao W, et al. Up-Regulated Expression of Matrix Metalloproteinases in Endothelial Cells Mediates Platelet Microvesicle-Induced Angiogenesis. Cell Physiol Biochem. 2017;41:2319-2332 pubmed 出版商
Conant K, Daniele S, Bozzelli P, Abdi T, Edwards A, Szklarczyk A, et al. Matrix metalloproteinase activity stimulates N-cadherin shedding and the soluble N-cadherin ectodomain promotes classical microglial activation. J Neuroinflammation. 2017;14:56 pubmed 出版商
Schumacher M, Hedl M, Abraham C, Bernard J, Lozano P, Hsieh J, et al. ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation. Cell Death Dis. 2017;8:e2622 pubmed 出版商
Greene J, Portillo J, Lopez Corcino Y, Subauste C. CD40-TRAF Signaling Upregulates CX3CL1 and TNF-α in Human Aortic Endothelial Cells but Not in Retinal Endothelial Cells. PLoS ONE. 2015;10:e0144133 pubmed 出版商
Son S, Kang S, Choi H, Mook Jung I. Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway. Mol Neurodegener. 2015;10:56 pubmed 出版商
Leung W, Vong Q, Lin W, Bouck D, Wendt S, Sullivan E, et al. PRL-3 mediates the protein maturation of ULBP2 by regulating the tyrosine phosphorylation of HSP60. J Immunol. 2015;194:2930-41 pubmed 出版商
Le Bras G, Taylor C, Koumangoye R, Revetta F, Loomans H, Andl C. TGF? loss activates ADAMTS-1-mediated EGF-dependent invasion in a model of esophageal cell invasion. Exp Cell Res. 2015;330:29-42 pubmed 出版商
产品信息
品牌 :
Tocris
master code :
2983
SKU号 :
2983/10
产品名称 :
GM 6001
描述 :
Broad spectrum MMP inhibitor
靶标 :
Synthetic Metalloprotease Inhibitors
类别 :
Small Molecules
单位尺寸 :
10毫克
纯度 :
95%
观察到的分子量 :
388.46
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
GM 6001 is a broad spectrum MMP inhibitor. Reduces infarct volume following middle cerebral artery occlusion in an ischemic mouse model. Also inhibits human skin fibroblast collagenase (Ki = 0.4 nM).
extended description :
Broad spectrum MMP inhibitor
化学品名文本 :
(2R)-N4-Hydroxy-N1-[(1S)-1-(1H-indol-3-ylmethyl)-2-(methylamino)-2-oxoethyl]-2-(2-methylpropyl)butanediamide
配方 :
C 20 H 28 N 4 O 4
配方文本 :
C20H28N4O4
cas num :
142880-36-2
美元 :
376美元
产品细节 :
Broad spectrum MMP inhibitor
别名 :
Galardin, Ilomastat
储存 :
存放在-20°C
更多信息或购买 :
Tocris Bioscience 产品网页
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国