1-Naphthyl PP1 | Tocris Bioscience 3063/10 产品信息

产品简要

公司名称 :

Tocris Bioscience

产品类型 :

化学品

产品名称 :

1-Naphthyl PP1

3063/10

规格 :

10 mg (also 50 mg)

价格 :

356美元

更多信息或购买 :

Tocris Bioscience 产品网页

文章摘录数: 6

参考文献
O Neill A, Kindberg A, Niethamer T, Larson A, Ho H, Greenberg M, et al. Unidirectional Eph/ephrin signaling creates a cortical actomyosin differential to drive cell segregation. J Cell Biol. 2016;215:217-229 pubmed
Chen X, Suhandynata R, Sandhu R, Rockmill B, Mohibullah N, Niu H, et al. Phosphorylation of the Synaptonemal Complex Protein Zip1 Regulates the Crossover/Noncrossover Decision during Yeast Meiosis. PLoS Biol. 2015;13:e1002329 pubmed 出版商
Meyer R, Chuong H, Hild M, Hansen C, Kinter M, Dawson D. Ipl1/Aurora-B is necessary for kinetochore restructuring in meiosis I in Saccharomyces cerevisiae. Mol Biol Cell. 2015;26:2986-3000 pubmed 出版商
Suhandynata R, Liang J, Albuquerque C, Zhou H, Hollingsworth N. A method for sporulating budding yeast cells that allows for unbiased identification of kinase substrates using stable isotope labeling by amino acids in cell culture. G3 (Bethesda). 2014;4:2125-35 pubmed 出版商
Kim S, Meyer R, Chuong H, Dawson D. Dual mechanisms prevent premature chromosome segregation during meiosis. Genes Dev. 2013;27:2139-46 pubmed 出版商
Lo H, Hollingsworth N. Using the semi-synthetic epitope system to identify direct substrates of the meiosis-specific budding yeast kinase, Mek1. Methods Mol Biol. 2011;745:135-49 pubmed 出版商

产品信息

品牌 :

Tocris

MasterCode :

3063

SKU号 :

3063/10

产品名称 :

1-Naphthyl PP1

靶标 :

Src Family Kinase Inhibitors

类别 :

Small Molecules

单位尺寸 :

10 mg (also 50 mg)

纯度 :

99%

观察到的分子量 :

317.39

网址印刷 :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

功能细节 :

1-Naphthyl PP1 is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl. (IC50 values are 1.0, 0.6, 0.6, 18 and 22 u M for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively). Preferentially inhibits mutant over wild-type kinases (IC50 values are 1.5 vs 1000 nM for I338G v-src and v-src respectively).

extended description :

Src family kinase inhibitor; also inhibits c-Abl

化学品名文本 :

1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

配方 :

C 19 H 19 N 5

配方文本 :

C19H19N5

cas num :

221243-82-9

美元 :

356美元

产品细节 :

Src family kinase inhibitor; also inhibits c-Abl

别名 :

1-NA-PP 1

储存 :

存放在+4°C

更多信息或购买 :

Tocris Bioscience 产品网页

公司信息

Tocris Bioscience

The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD

info@bio-techne.com

https://www.tocris.com

800-343-7475

公司总部: 英国