产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
SU 16f
目录 :
3304/10
规格 :
10 mg (also 50 mg)
价格 :
289美元
更多信息或购买 :
Tocris Bioscience 产品网页
文章摘录数: 5
参考文献
Novak S, Madunic J, Shum L, Vučetić M, Wang X, Tanigawa H, et al. PDGF inhibits BMP2-induced bone healing. NPJ Regen Med. 2023;8:3 pubmed 出版商
Chatterjee S, Bhat V, Berdnikov A, Liu J, Zhang G, Buchel E, et al. Paracrine Crosstalk between Fibroblasts and ER+ Breast Cancer Cells Creates an IL1β-Enriched Niche that Promotes Tumor Growth. iScience. 2019;19:388-401 pubmed 出版商
Jiang Y, Berry D, Jo A, Tang W, Arpke R, Kyba M, et al. A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion. Nat Commun. 2017;8:15926 pubmed 出版商
Andersen R, Zaher W, Larsen K, Ditzel N, Drews K, Wruck W, et al. Association between in vivo bone formation and ex vivo migratory capacity of human bone marrow stromal cells. Stem Cell Res Ther. 2015;6:196 pubmed 出版商
Lee E, Pandey N, Popel A. Lymphatic endothelial cells support tumor growth in breast cancer. Sci Rep. 2014;4:5853 pubmed 出版商
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
3304
SKU号 :
3304/10
产品名称 :
SU 16f
描述 :
Potent and selective PDGFR inhibitor
靶标 :
PDGF Receptor Inhibitors
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
98%
观察到的分子量 :
386.44
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
SU 16f is a potent and selective platelet-derived growth factor receptor (PDGFR ) inhibitor (IC50 = 10 nM) that displays 14-fold, 229-fold and 10000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively. Inhibits proliferation of HUVEC and NIH3T3 cells in vitro (IC50 = 0.11 M). Promotes conversion of fibroblasts to cardiomyocytes as part of 9C cocktail. . For more information about how SU 16f may be used, see our protocol: Converting Fibroblasts into Cardiomyocytes (9C Cocktail)
extended description :
Potent and selective PDGFR inhibitor
化学品名文本 :
5-[1,2-Dihydro-2-oxo-6-phenyl-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid
配方 :
C 24 H 22 N 2 O 3
配方文本 :
C24H22N2O3
cas num :
251356-45-3
美元 :
289美元
产品细节 :
Potent and selective PDGFR inhibitor
储存 :
存放在RT
更多信息或购买 :
Tocris Bioscience 产品网页
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国