产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
8-(3-Chlorostyryl)caffeine
目录 :
3306/10
规格 :
10 mg (also 50 mg)
价格 :
124美元
更多信息或购买 :
文章摘录数: 5
参考文献
Kleiner J, Hollborn M, Wiedemann P, Bringmann A. Activator protein-1 contributes to the NaCl-induced expression of VEGF and PlGF in RPE cells. Mol Vis. 2018;24:647-666 pubmed
Benada J, Burdová K, Lidak T, von Morgen P, Macurek L. Polo-like kinase 1 inhibits DNA damage response during mitosis. Cell Cycle. 2015;14:219-31 pubmed 出版商
Li H, Chuang A, O BRIEN J. Regulation of photoreceptor gap junction phosphorylation by adenosine in zebrafish retina. Vis Neurosci. 2014;31:237-43 pubmed 出版商
Bao Y, Chen Y, Ledderose C, Li L, Junger W. Pannexin 1 channels link chemoattractant receptor signaling to local excitation and global inhibition responses at the front and back of polarized neutrophils. J Biol Chem. 2013;288:22650-7 pubmed 出版商
Factor P, Mutlu G, Chen L, Mohameed J, Akhmedov A, Meng F, et al. Adenosine regulation of alveolar fluid clearance. Proc Natl Acad Sci U S A. 2007;104:4083-8 pubmed
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
3306
SKU号 :
3306/10
产品名称 :
8-(3-Chlorostyryl)caffeine
描述 :
Selective A2A antagonist. Also MAO-B inhibitor
靶标 :
Adenosine A2a Receptor Antagonists
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
99%
观察到的分子量 :
330.77
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
8-(3-Chlorostyryl)caffeine is a selective adenosine A2A receptor antagonist and monoamine oxidase B (MAO-B) inhibitor (Ki values are 54 and 28200 nM at rat A2A and A1 receptors respectively and Ki ~ 100 nM at MAO-B). Potently protects against quinolinic acid -induced (Cat. No. 0225) neuronal damage and is neuroprotective in the MPTP model of Parkinson s disease.
extended description :
Selective A2A antagonist. Also MAO-B inhibitor
化学品名文本 :
(E)-8-[2-(3-Chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
配方 :
C 16 H 15 ClN 4 O 2
配方文本 :
C16H15ClN4O2
cas num :
147700-11-6
美元 :
124美元
产品细节 :
Selective A2A antagonist. Also MAO-B inhibitor
别名 :
CSC
储存 :
存放在-20°C
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国