产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
BzATP triethylammonium salt
目录 :
3312/1
规格 :
1毫克
价格 :
98美元
更多信息或购买 :
文章摘录数: 6
参考文献
Pronin A, Pham D, An W, Dvoriantchikova G, Reshetnikova G, Qiao J, et al. Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury. Front Mol Neurosci. 2019;12:36 pubmed 出版商
Karmakar M, Katsnelson M, Dubyak G, Pearlman E. Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP. Nat Commun. 2016;7:10555 pubmed 出版商
Ilatovskaya D, Palygin O, Levchenko V, Staruschenko A. Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli. Am J Physiol Cell Physiol. 2013;305:C1050-9 pubmed 出版商
Shabir S, Cross W, Kirkwood L, Pearson J, Appleby P, Walker D, et al. Functional expression of purinergic P2 receptors and transient receptor potential channels by the human urothelium. Am J Physiol Renal Physiol. 2013;305:F396-406 pubmed 出版商
Nörenberg W, Sobottka H, Hempel C, Plötz T, Fischer W, Schmalzing G, et al. Positive allosteric modulation by ivermectin of human but not murine P2X7 receptors. Br J Pharmacol. 2012;167:48-66 pubmed 出版商
Woehrle T, Yip L, Manohar M, Sumi Y, Yao Y, Chen Y, et al. Hypertonic stress regulates T cell function via pannexin-1 hemichannels and P2X receptors. J Leukoc Biol. 2010;88:1181-9 pubmed 出版商
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
3312
SKU号 :
3312/1
产品名称 :
BzATP triethylammonium salt
描述 :
Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist
靶标 :
P2X Receptor Agonists
类别 :
Small Molecules
单位尺寸 :
1毫克
纯度 :
95%
观察到的分子量 :
1018.97
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
BzATP triethylammonium salt is a prototypic P2X7 receptor agonist (EC50 values are 3.6, 7 and 285 M for rat, human and mouse receptors respectively). Exhibits 5 - 10 fold greater potency than ATP. Exhibits partial agonist activity at P2X1 (pEC50 = 8.7) and P2Y1 receptors and can be used as a photoaffinity label for ATPase. . This compound is a mixture of isomers.
extended description :
Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist
化学品名文本 :
2 (3 )-O-(4-Benzoylbenzoyl)adenosine-5 -triphosphate tri(triethylammonium) salt
配方 :
C 24 H 24 N 5 O 15 P 3。 C 18 H 45 N 3
配方文本 :
C24H24N5O15P3.C18H45N3
美元 :
98美元
产品细节 :
Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist
储存 :
存放在-20°C
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国