产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
10Panx
目录 :
3348/1
规格 :
1毫克
价格 :
171美元
更多信息或购买 :
Tocris Bioscience 产品网页
文章摘录数: 8
参考文献
Hudson G, Flannigan K, Venu V, Alston L, Sandall C, MacDonald J, et al. Pregnane X Receptor Activation Triggers Rapid ATP Release in Primed Macrophages That Mediates NLRP3 Inflammasome Activation. J Pharmacol Exp Ther. 2019;370:44-53 pubmed 出版商
Chen W, Zhu S, Wang Y, Li J, Qiang X, Zhao X, et al. Enhanced Macrophage Pannexin 1 Expression and Hemichannel Activation Exacerbates Lethal Experimental Sepsis. Sci Rep. 2019;9:160 pubmed 出版商
Kleiner J, Hollborn M, Wiedemann P, Bringmann A. Activator protein-1 contributes to the NaCl-induced expression of VEGF and PlGF in RPE cells. Mol Vis. 2018;24:647-666 pubmed
Barría I, Güiza J, Cifuentes F, Zamorano P, Saez J, Gonzalez J, et al. Trypanosoma cruzi Infection Induces Pannexin-1 Channel Opening in Cardiac Myocytes. Am J Trop Med Hyg. 2018;98:105-112 pubmed 出版商
Albalawi F, Lu W, Beckel J, Lim J, McCaughey S, Mitchell C. The P2X7 Receptor Primes IL-1β and the NLRP3 Inflammasome in Astrocytes Exposed to Mechanical Strain. Front Cell Neurosci. 2017;11:227 pubmed 出版商
Adamczyk M, Griffiths R, Dewitt S, Knauper V, Aeschlimann D. P2X7 receptor activation regulates rapid unconventional export of transglutaminase-2. J Cell Sci. 2015;128:4615-28 pubmed 出版商
Kowal J, Haanes K, Christensen N, Novak I. Bile acid effects are mediated by ATP release and purinergic signalling in exocrine pancreatic cells. Cell Commun Signal. 2015;13:28 pubmed 出版商
Manohar M, Hirsh M, Chen Y, Woehrle T, Karande A, Junger W. ATP release and autocrine signaling through P2X4 receptors regulate ?? T cell activation. J Leukoc Biol. 2012;92:787-94 pubmed 出版商
产品信息
品牌 :
Tocris, a Bio-Techne Brand
catalog number base :
3348
SKU号 :
3348/1
产品名称 :
10Panx
描述 :
Panx-1 mimetic inhibitory peptide; blocks pannexin-1 gap junctions
靶标 :
Gap Channel Blockers
类别 :
肽
单位尺寸 :
1毫克
纯度 :
95%
观察到的分子量 :
1242.37
网址印刷 :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides
功能细节 :
10Panx is a panx-1 mimetic inhibitory peptide that blocks pannexin-1 gap junctions. Inhibits P2X7-mediated dye uptake, ATP-mediated IL-1 release and caspase-1 activation without altering membrane current in macrophages in vitro . Also blocks activation of NMDA receptor secondary currents (I2nd) by 70%.
extended description :
Panx-1 mimetic inhibitory peptide; blocks pannexin-1 gap junctions
配方 :
C 58 H 79 N 15 O 16
配方文本 :
C58H79N15O16
cas num :
955091-53-9
美元 :
171美元
产品细节 :
Panx-1 mimetic inhibitory peptide; blocks pannexin-1 gap junctions
储存 :
存放在-20°C
更多信息或购买 :
Tocris Bioscience 产品网页
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国