产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
DQP 1105
目录 :
4491/10
规格 :
10 mg (also 50 mg)
价格 :
227美元
更多信息或购买 :
Tocris Bioscience 产品网页
文章摘录数: 2
参考文献
Brancaccio M, Patton A, Chesham J, Maywood E, Hastings M. Astrocytes Control Circadian Timekeeping in the Suprachiasmatic Nucleus via Glutamatergic Signaling. Neuron. 2017;93:1420-1435.e5 pubmed 出版商
Lozovaya N, Gataullina S, Tsintsadze T, Tsintsadze V, Pallesi Pocachard E, Minlebaev M, et al. Selective suppression of excessive GluN2C expression rescues early epilepsy in a tuberous sclerosis murine model. Nat Commun. 2014;5:4563 pubmed 出版商
产品信息
品牌 :
Tocris
master code :
4491
SKU号 :
4491/10
rank :
0.061
产品名称 :
DQP 1105
描述 :
GluN2C/GluN2D-selective NMDA antagonist
靶标 :
NMDA Receptor Antagonists
类别 :
Small Molecules
sizes available :
10 mg (also 50 mg)
网址印刷 :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
DQP 1105 is a noncompetitive NMDA receptor antagonist; displays over 50-fold selectivity for GluN2D- and GluN2C-containing receptors over GluN2B-, GluK2-, GluA1- and GluN2A-containing receptors (IC50 values are 2.7, 8.5, 121, 153, 198 and 206 M, respectively). Reduces frequency of channel opening. . Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions .
extended description :
GluN2C/GluN2D-selective NMDA antagonist
化学品名文本 :
5-(4-Bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro- -oxo-1H-pyrazole-1-butanoic acid
配方 :
C 29 H 24 BrN 3 O 4
配方文本 :
C29H24BrN3O4
cas num :
380560-89-4
美元 :
227美元
产品细节 :
GluN2C/GluN2D-selective NMDA antagonist
储存 :
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
更多信息或购买 :
Tocris Bioscience 产品网页
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国