产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
T16Ainh - A01
目录 :
4538/10
规格 :
10 mg (also 50 mg)
价格 :
185美元
更多信息或购买 :
Tocris Bioscience 产品网页
文章摘录数: 8
参考文献
Kusuda Y, Kondo Y, Miyagi Y, Munemasa T, Hori Y, Aonuma F, et al. Long-term dexamethasone treatment diminishes store-operated Ca2+ entry in salivary acinar cells. Int J Oral Sci. 2019;11:1 pubmed 出版商
Zhang W, Schmelzeisen S, Parthier D, Frings S, Möhrlen F. Anoctamin Calcium-Activated Chloride Channels May Modulate Inhibitory Transmission in the Cerebellar Cortex. PLoS ONE. 2015;10:e0142160 pubmed 出版商
Pineda Farias J, Barragán Iglesias P, Loeza Alcocer E, Torres López J, Rocha González H, Pérez Severiano F, et al. Role of anoctamin-1 and bestrophin-1 in spinal nerve ligation-induced neuropathic pain in rats. Mol Pain. 2015;11:41 pubmed 出版商
Zhang Y, Wang X, Wang H, Jiao J, Li Y, Fan E, et al. TMEM16A-Mediated Mucin Secretion in IL-13-Induced Nasal Epithelial Cells From Chronic Rhinosinusitis Patients. Allergy Asthma Immunol Res. 2015;7:367-75 pubmed 出版商
Bijos D, Drake M, Vahabi B. Anoctamin-1 in the juvenile rat urinary bladder. PLoS ONE. 2014;9:e106190 pubmed 出版商
Bill A, Hall M, Borawski J, Hodgson C, Jenkins J, Piechon P, et al. Small molecule-facilitated degradation of ANO1 protein: a new targeting approach for anticancer therapeutics. J Biol Chem. 2014;289:11029-41 pubmed 出版商
Harper M, Poole A. Chloride channels are necessary for full platelet phosphatidylserine exposure and procoagulant activity. Cell Death Dis. 2013;4:e969 pubmed 出版商
Jeon J, Paik S, Chun M, Oh U, Kim I. Presynaptic Localization and Possible Function of Calcium-Activated Chloride Channel Anoctamin 1 in the Mammalian Retina. PLoS ONE. 2013;8:e67989 pubmed 出版商
产品信息
品牌 :
Tocris
master code :
4538
SKU号 :
4538/10
rank :
0.061
产品名称 :
T16Ainh - A01
描述 :
Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A) inhibitor
靶标 :
Calcium-activated Chloride Channel Blockers
类别 :
Small Molecules
sizes available :
10 mg (also 50 mg)
网址印刷 :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
T16Ainh - A01 is an inhibitor of Ca2+-dependent Cl- channel (CaCC) transmembrane protein 16A (TMEM16A) (IC50 = 1.8 M in A253 salivary gland epithelial cells). Inhibits EGF-induced increases in CaCC currents; blocks proliferation of tumor cells in vitro .
extended description :
Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A) inhibitor
化学品名文本 :
2-[(5-Ethyl-1,6-dihydro-4-methyl-6-oxo-2-pyrimidinyl)thio]-N-[4-(4-methoxyphenyl)-2-thiazolyl]acetamide
配方 :
C 19 H 20 N 4 O 3秒2
配方文本 :
C19H20N4O3S2
cas num :
552309-42-9
美元 :
185美元
产品细节 :
Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A) inhibitor
储存 :
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
更多信息或购买 :
Tocris Bioscience 产品网页
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国