产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
Purmorphamine
目录 :
4551
规格 :
10 mg (also 50 mg)
价格 :
227美元
更多信息或购买 :
文章摘录数: 8
参考文献
Hackland J, Shelar P, Sandhu N, Prasad M, Charney R, Gomez G, et al. FGF Modulates the Axial Identity of Trunk hPSC-Derived Neural Crest but Not the Cranial-Trunk Decision. Stem Cell Reports. 2019;12:920-933 pubmed 出版商
Yuan X, Cao X, Yang S. IFT80 is required for stem cell proliferation, differentiation, and odontoblast polarization during tooth development. Cell Death Dis. 2019;10:63 pubmed 出版商
Lang C, Campbell K, Ryan B, Carling P, Attar M, Vowles J, et al. Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes. Cell Stem Cell. 2019;24:93-106.e6 pubmed 出版商
Kaindl J, Meiser I, Majer J, Sommer A, Krach F, Katsen Globa A, et al. Zooming in on Cryopreservation of hiPSCs and Neural Derivatives: A Dual-Center Study Using Adherent Vitrification. Stem Cells Transl Med. 2019;8:247-259 pubmed 出版商
Sheng C, Jungverdorben J, Wiethoff H, Lin Q, Flitsch L, Eckert D, et al. A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation. Nat Commun. 2018;9:4047 pubmed 出版商
Sommer A, Marxreiter F, Krach F, Fadler T, Grosch J, Maroni M, et al. Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease. Cell Stem Cell. 2018;23:123-131.e6 pubmed 出版商
Rajamani U, Gross A, Hjelm B, Sequeira A, Vawter M, Tang J, et al. Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses. Cell Stem Cell. 2018;22:698-712.e9 pubmed 出版商
Yuan X, Cao J, He X, Serra R, Qu J, Cao X, et al. Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation. Nat Commun. 2016;7:11024 pubmed 出版商
产品信息
品牌 :
Tocris
master code :
4551
SKU号 :
4551/10
产品名称 :
Purmorphamine
描述 :
Smo receptor agonist
靶标 :
Smoothened Receptor Agonists
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
纯度 :
98%
观察到的分子量 :
520.62
网址印刷 :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
Smoothened (Smo) receptor agonist (EC50 ~ 1 M). Induces osteogenesis in mouse mesenchymal progenitor cells (C3H10T1/2). When combined with BMP-4, can transdifferentiate pre-adipocytes (3T3-L1) and myoblasts (C2C12) into osteoblasts. Induces differentiation of multipotent mesenchymal progenitor cells into osteoblasts.
catalog number base :
4551
产品关键词 :
Smoothened Smo receptors agonists differentiation multipotent mesenchymal progenitor cells osteoblasts osteogenic Smoothened Receptors Mesenchymal Stem Cells Osteogenic Stem Cells 4551,
extended description :
Smo receptor agonist
化学品名文本 :
9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine
配方 :
C 31 H 32 N 6 O 2
配方文本 :
C31H32N6O2
cas num :
483367-10-8
2020美元 :
216
2021美元 :
227美元
储存 :
存放在-20°C
更多信息或购买 :
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国