化学品

CHR 6494 trifluoroacetate

5326/10

10毫克

194美元

5326

5326/10

0.061

CHR 6494 trifluoroacetate

Potent and selective haspin inhibitor

Haspin Inhibitors

Small Molecules

10毫克

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CHR 6494 trifluoroacetate is a potent and selective haspin kinase inhibitor (IC50 = 2 nM). Selective over 27 other protein kinases including Aurora B kinase. Induces cell cycle arrest at G2/M, inhibits cell proliferation and promotes apoptosis in multiple cancer cell lines. Inhibits angiogenesis ex vivo and attenuates tumor growth of HCT-116 xenografts in rats.

Potent and selective haspin inhibitor

3-(1H-Indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine trifluoroacetate

C 16 H 16 N 6。 CF 3 CO 2 H

C16H16N6.CF3CO2H

1458630-17-5

194美元

Potent and selective haspin inhibitor

Store the unopened product at 2 - 8 °C. Do not use past expiration date.