产品简要
公司名称 :
Tocris Bioscience
产品类型 :
化学品
产品名称 :
C34
目录 :
5373/10
规格 :
10 mg (also 50 mg)
价格 :
157美元
更多信息或购买 :
Tocris Bioscience 产品网页
文章摘录数: 8
参考文献
D Agostino M, Beji S, Sileno S, Lulli D, Mercurio L, Madonna S, et al. Extracellular Nucleophosmin Is Increased in Psoriasis and Correlates With the Determinants of Cardiovascular Diseases. Front Cardiovasc Med. 2022;9:867813 pubmed 出版商
Beji S, D Agostino M, Gambini E, Sileno S, Scopece A, Vinci M, et al. Doxorubicin induces an alarmin-like TLR4-dependent autocrine/paracrine action of Nucleophosmin in human cardiac mesenchymal progenitor cells. BMC Biol. 2021;19:124 pubmed 出版商
Park H, Hong J, Yin Y, Joo Y, Kim Y, Shin J, et al. TAP2, a peptide antagonist of Toll-like receptor 4, attenuates pain and cartilage degradation in a monoiodoacetate-induced arthritis rat model. Sci Rep. 2020;10:17451 pubmed 出版商
Yamamoto M, Kim M, Imai H, Itakura Y, Ohtsuki G. Microglia-Triggered Plasticity of Intrinsic Excitability Modulates Psychomotor Behaviors in Acute Cerebellar Inflammation. Cell Rep. 2019;28:2923-2938.e8 pubmed 出版商
Zhou J, Yang Y, Gan T, Li Y, Hu F, Hao N, et al. Lung cancer cells release high mobility group box 1 and promote the formation of neutrophil extracellular traps. Oncol Lett. 2019;18:181-188 pubmed 出版商
Stephens M, Liao S, von der Weid P. Mesenteric Lymphatic Alterations Observed During DSS Induced Intestinal Inflammation Are Driven in a TLR4-PAMP/DAMP Discriminative Manner. Front Immunol. 2019;10:557 pubmed 出版商
Zhang Z, La Placa D, Nguyen T, Kujawski M, Le K, Li L, et al. CEACAM1 regulates the IL-6 mediated fever response to LPS through the RP105 receptor in murine monocytes. BMC Immunol. 2019;20:7 pubmed 出版商
Sun L, Li M, Ma X, Feng H, Song J, Lv C, et al. Inhibition of HMGB1 reduces rat spinal cord astrocytic swelling and AQP4 expression after oxygen-glucose deprivation and reoxygenation via TLR4 and NF-?B signaling in an IL-6-dependent manner. J Neuroinflammation. 2017;14:231 pubmed 出版商
图像
图像 1 :
Tocris Bioscience 5373/10 图像 1
Cat.No. 5373 - C34 C17H27NO9 CAS No. 40592-88-9
产品信息
品牌 :
Tocris
MasterCode :
5373
SKU号 :
5373/10
产品名称 :
C34
靶标 :
Toll-like Receptor Inhibitors
类别 :
Small Molecules
单位尺寸 :
10 mg (also 50 mg)
观察到的分子量 :
389.4
网址印刷 :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
功能细节 :
C34 is a TLR4 inhibitor; attenuates TLR4 signaling in enterocytes and macrophages in vitro , and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis (NEC). Also suppresses LPS signaling in human ileum displaying NEC ex-vivo . Displays no significant effects on signaling via TLR2 or TLR9.
extended description :
TLR4 inhibitor
化学品名文本 :
1-Methylethyl 2-(acetylamino)-2-deoxy- -D-glucopyranoside 3,4,6-triacetate
配方 :
C 17 H 27 NO 9
配方文本 :
C17H27NO9
cas num :
40592-88-9
美元 :
157美元
产品细节 :
TLR4 inhibitor
别名 :
Toll样受体4-在
储存 :
存放在-20°C
更多信息或购买 :
Tocris Bioscience 产品网页
公司信息
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
公司总部: 英国