产品简要
公司名称 :
Toronto BioScience
产品类型 :
抗体
产品名称 :
脂联素(人类), 兔多克隆
目录 :
11010
规格 :
100微克
价格 :
194美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
nonconjugated
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定
更多信息或购买 :
文章摘录数: 5
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产品信息
目录代码 :
11010
产品名称 :
脂联素(人类), 兔多克隆
宿主物种 :
兔
克隆性 :
多克隆
共轭 :
纯化
产品类型 :
抗体
规格 :
100微克
标价(美元) :
194美元
Pubmed号列表 :
26417088, 26166748, 25915851, 25961840, 25071026
抗体亚型 :
兔IgG
产品描述 :
This rabbit polyclonal antibody can detect three types of circular human adiponectin and monomer (30kDa) adiponectin by ELISA and by Western Blot.
物种摘要 :
人类特异性
背景 :
Adiponectin, also termed gelatin-binding protein-28 (GBP28), AdipoQ, ACP30 (Acrp30), or apM, is a major adipocyte-secreted adipokine which abundantly present in the circulation as three distinct oligomeric complexes: LMW(67kDa), MMW(167kDa) and HMW(300kDa) adiponectin. Its levels are decreased in insulin resistant, diabetes and cardiovascular disease. Conversely, elevation of circulating adiponectin concentrations can alleviate various vascular dysfunctions in animal models, suggesting this adipokine exerts vasculoprotective effects. In addition, adiponectin may also be of importance in the development and progression of several malignancies.
别名 :
Adiponectin is also known as apM1, Acrp30, GBP28 and adipoQ.
免疫原 :
Recombinant full-length human adiponectin expressed in mammalian cells
特异性 :
人类
缓冲液 :
溶液在PBS
用途 :
Western blot - This antibody can be used at 0.1 - 0.2 μg/mL with the appropriate secondary reagents to detect human adiponectin.
ELISA - This antibody can be used at 0.5 - 1.0 μg/mL with the appropriate secondary reagents to detect human Adiponectin.
应用摘要 :
Western blot - This antibody can be used at 0.1 - 0.2 μg/mL with the appropriate secondary reagents to detect human adiponectin.
ELISA - This antibody can be used at 0.5 - 1.0 μg/mL with the appropriate secondary reagents to detect human Adiponectin.
储存 :
Store at –20°C. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.
一般参考 :
[1] Xu A, et al. (2005) Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes. J. Biol. Chem. 280, 18073–18080 [2] Xu A, et al. (2008) Selective Elevation of Adiponectin Production by the Natural Compounds Derived from a Medicinal Herb Alleviates Insulin Resistance and Glucose Intolerance in Obese Mice. Endocrinology. [Epub ahead of print]
[3] Xu A, et al. (2004) Adiponectin ameliorates dyslipidemia induced by the human immunodeficiency virus protease inhibitor ritonavir in mice. Endocrinology. 145(2):487-94
[4] Wang Y, et al. (2008) Post-translational modifications of adiponectin: mechanisms and functional implications. Biochem J. 409(3):623-33
产品引用 :
Journal American Heart Association 2013 [2(1):e004176]; Arterioscler Thromb Vasc Biol. 2014 Nov;34(11):2457-64; Endocrinology. 145(2):487-94
更多信息或购买 :
公司信息
Toronto BioScience